Dr Karan Explores

OG Podcasts

Join Dr Karan Rajan, medical doctor, Founder of LOAM Science, Chief of Science at Throne Science, and Sunday Times bestselling author as he meets the world's foremost experts in science and medicine to cut through the BS of modern health advice. One of the most-followed medical voices online, with over 10 million followers worldwide. New episodes every week.

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May 11 · 56 min
The Gut Health Myths You Still Believe (And What Actually Works)
Your gut microbiome affects far more than digestion. In this episode, Dr Karan Rajan sits down with gut health expert Jordan Haworth to break down the science of gut health, probiotics, fibre, acid reflux, oral microbiome health, fermented foods, GLP-1, bloating, sleep, fasting, and the everyday habits that actually improve your microbiome. Here is a link to preorder Jordan's new book out June 18th: How to Gut Health: Science-backed hacks for immunity, metabolism and better sleep https://lnk.to/howtoguthealth We speak about: The connection between oral health and gut health Why chewing food properly changes digestion The truth about probiotics and fermented foods Best foods for beneficial gut bacteria Gut-friendly habits that improve digestion naturally Acid reflux hacks backed by science Whether greens powders and fibre gummies are worth it The role of fasting, sleep, exercise and stress on the microbiome Why gut health affects metabolism, immunity, mood and more 00:00 Gut Health Starts In The Mouth 01:15 Why Chewing Improves Digestion 04:10 Eating Slowly, GLP-1 & Feeling Full 06:55 Oral Microbiome, Mouthwash & Gum Disease 11:25 Acid Reflux & The Lower Oesophageal Sphincter 19:40 Bitter Foods, Coffee & Digestion 22:05 Nausea, Ginger & Fart Walking 31:00 Foods That Feed Bifidobacteria 34:00 Fermented Foods & Lactic Acid Bacteria 37:50 Slow-Fermenting Fibres For The Colon 40:35 Prebiotics, Probiotics & Postbiotics Explained 50:40 Nature, Sleep, Exercise & The Microbiome 53:10 Fasting, Akkermansia & Gut Rest 54:45 Sweeteners, Vinegar, Greens Powders & Fibre Gummies Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10. Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe Discover Throne's incredible new smart toilet device at http://thronescience.com For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation Discover my digital twin here: http://DrKaran.ai Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlist About Dr Karan: Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. Connect with me: Instagram: / drkaranrajan Facebook: / drkaran TikTok: / dr.karanr X: / drkaranrajan Website: www.drkaranrajan.com #GutHealth #Microbiome #DigestiveHealth #Probiotics #DrKaran
May 4 · 53 min
Why Nothing Feels Fun Anymore: Dopamine, Phones & Brain Rot
Your phone is not just distracting you, it may be changing what your brain finds rewarding. In this episode of Dr Karan Explores, Dr Karan Rajan speaks with neuroscientist TJ Power, founder of DOSE Lab, about dopamine, phone addiction, AI, “brain rot,” digital anhedonia, and why modern technology can make ordinary life feel less pleasurable. TJ’s DOSE framework focuses on dopamine, oxytocin, serotonin, and endorphins, the four brain chemicals he says are being disrupted by the way modern humans live. This conversation explores why so many of us feel stuck in loops of scrolling, distraction, apathy, and low motivation, and what it takes to reset our relationship with stimulation without pretending technology is “bad.” TJ shares why he believes 72 hours without screens can feel transformative, why boredom is harder than it sounds, and why becoming a “professional unplugger” may be one of the most important skills for the next generation. In this episode, we cover: What dopamine actually does beyond the online “dopamine detox” clichés Why phones, short-form content, sugar, alcohol, and AI can hijack reward pathways “Digital anhedonia”: Why normal life can start to feel dull or boring The 72-hour unplugged experiment and what happens by day two and day three Why boredom, stillness, walking, and doing nothing can restore creativity The default mode network and why your best ideas may need silence AI, “brain rot,” passive screen time, and outsourcing your thinking How to become a “professional unplugger” without quitting modern life 🎬 Chapters 01:13 – Why Modern Life Is Rewiring Our Brains 03:18 – What Dopamine Actually Does 06:06 – Phones, Short-Form Content & Dopamine Overload 09:28 – Why Nothing Feels Fun Anymore 12:27 – How to Break the Stimulation Loop 14:01 – 72 Hours Without Screens: What Happens to Your Brain 17:49 – Boredom, Creativity & the Default Mode Network 21:41 – Instant Gratification and the Collapse of Waiting 22:47 – AI, Brain Rot & Outsourcing Your Thinking 29:34 – Passive Screen Time vs Active Technology Use 32:37 – Are Some Brains More Dopamine-Hungry? 39:04 – Stillness, Silence & Rebuilding Attention 42:35 – AI Relationships, Oxytocin & Artificial Connection 46:10 – Why Technology Evolves Faster Than the Human Brain 48:27 – Dopamine and Why Time Feels Faster 52:03 – Becoming a Professional Unplugger 53:31 – Final Takeaway: Quiet Mornings, Coffee & No Phone 💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10.💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation🤖 Discover my digital twin here: http://DrKaran.ai🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlistAbout Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.📱Connect with me:Instagram: / drkaranrajanFacebook: / drkaranrTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com #Dopamine #BrainRot #PhoneAddiction #Neuroscience #DigitalDetox
April 30 · 43 min
We STILL Don’t Understand Childbirth | Dr Jennifer Lincoln
💬 Protecting first time parents from the realities of childbirth comes at a price. Not knowing how difficult it can be often leaves them unprepared - feeling guilty if it doesn’t go “perfectly”. ⚡With all the misinformation around - and shockingly high maternal mortality rates in the US - Dr Jennifer Lincoln has decided to take childbirth into her own hands. The social media educator has just released The Birth Book: An OB-GYN’s Guide to Demystifying Labor and Delivery. 🎧 Stay tuned to find out: ➡ What a “normal” labour really looks like ➡︎ What you can say “no” to during labour (Hint: anything) ➡︎ The truth about epidurals, C-sections and natural birth ➡︎ That children can be healthy no matter how childbirth goes ➡︎ Why the US is the highest rich nation for maternal mortality ➡︎ How 1 in 3 births cause psychological trauma for the mum #DrKaran, #Pregnancy, #BirthScience, #Labour, #BirthTrauma, #ChildbirthMyths #WomensHealth, #MedicalScience, #HealthEducation, #MythBusting Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 📕 Chapters (0:00) Introduction - We need to be realistic about childbirth (2:10) How should women really prepare for birth? (3:27) Are doctors good patients when it comes to childbirth? (5:16) What does a normal first time labour really look like? (7:11) How to know when it’s time to go to the hospital (8:28) Should you pack a hospital bag? (10:07) What it really means to induce labour (14:09) Is there a best birthing position? (16:37) What can you say “no” to? (18:54) How to tell the difference between optional and necessary interventions (20:23) How different is second time labour? (22:38) What to do when a baby’s breach (24:22) Why you shouldn’t feel guilty about an epidural (28:51) Does vaginal seeding help? (29:25) Conversations to have before labour starts (31:56) The problem of “maternity deserts” in the US (34:52) Why maternal mortality is so high in the US (35:57) Why do black women have the worst childbirth outcomes? (39:16) What to consider if you’re having a homebirth (40:09) Why traumatic births are much more common than we realise 🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 🤖 Discover my digital twin here: http://DrKaran.ai 🔥 Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10. 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe 🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5 🎙️ An OG Podcasts production. About Dr Karan: Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health. 📱Connect with me: Instagram: https://www.instagram.com/drkaranrajan/ Facebook: https://www.facebook.com/DrKaranR/ TikTok: https://www.tiktok.com/@dr.karanr X: https://twitter.com/drkaranrajan Website: https://linktr.ee/ThisisVitalInformation
April 27 · 52 min
The Truth About GLP-1s, Food Noise & Weight Loss Drugs: Dr Federica Amati
GLP-1 weight loss drugs are changing medicine, but are we talking about them in the right way? In this episode, Dr Karan Rajan speaks with Dr Federica Amati about GLP-1s, food noise, metabolic health, appetite, gut health, muscle loss, side effects and why nutrition support matters. Dr Federica Amati explains why these medications should not be seen as simple “weight loss drugs”, how food noise differs from real hunger, and what people should know before, during and after GLP-1 treatment. 📗 Pre-order Dr Federica's book 'The Appetite Reset' here: https://shor.by/fP5H In this conversation, we cover: * Why diet remains one of the biggest drivers of chronic disease * What GLP-1s actually do beyond weight loss * The difference between homeostatic hunger, hedonic hunger and microbiome-driven hunger * Why food noise can dominate appetite and eating behaviour * How protein and resistance training can help protect muscle * Why micronutrients, fibre and hydration matter on GLP-1s * The risks of black market or poorly regulated weight loss injections * How gut health may influence appetite, side effects and long-term success * Why whole foods and nutrient density still matter most Chapters 00:00 Preview: GLP-1s, food noise and diet 01:18 Welcome and Dr Federica Amati introduction 02:18 Why GLP-1s need lifestyle and nutrition support 03:21 Diet, chronic disease and preventable deaths 05:08 Who should be using GLP-1 medications? 07:18 Why GLP-1s are metabolic health medications 08:13 GLP-1s, the brain and food noise 08:51 Homeostatic, hedonic and microbiome-driven hunger 09:22 Internal vs external food noise 11:37 Practical ways to reduce food noise 13:40 Loam sponsor read 14:39 Why digestion starts in the brain 17:29 Fullness, stomach stretch and meal replacements 19:47 GLP-1s, muscle loss, protein and resistance training 21:02 Micronutrients, hydration and nutrient density 24:06 Supplements and Mediterranean dietary patterns 26:10 Body image, identity and emotional changes on GLP-1s 28:34 Regulation, TikTok access and black market risks 30:47 Gut microbiome, appetite and natural GLP-1 signalling 42:31 Preparing your gut, managing side effects and final advice 💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10. 💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe 🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com 📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook 📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation 🤖 Discover my digital twin here: http://DrKaran.ai 🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlist About Dr Karan: Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health. 📱Connect with me: Instagram: / drkaranrajan Facebook: / drkaranr TikTok: / dr.karanr X: / drkaranrajan Website: www.drkaranrajan.com #GLP1 #WeightLossDrugs #FoodNoise #GutHealth #MetabolicHealth
April 23 · 29 min
How Can You Trust A Supplement Actually Works? | Dr Amine Zorgani
💬 How can you tell if a supplement actually does what it promises to do? There are so many on the market that are underdosed, understudied and not backed up by science. So before you choose your next supplement - this is the data that should inform your decision. ⚡When Dr Karan created LOAM, his aim was to create a fibre supplement backed up by clinically robust data. In this special episode, he outlines the lengthy process that went into making sure it actually delivers results. 🎧 Stay tuned to find out: ➡ What a preclinical study is - and why they are essential ➡︎ How a study can actually show you what’s going on inside someone’s gut ➡︎ Why propionate is so important for gut health - and how LOAM boosts it ➡︎ Why LOAM produces less gas and bloating than other fibre supplements ➡︎ What trials are coming in the future for LOAM #DrKaran, #LOAM, #Supplements, #Microbiome, #Butyrate, #GutHealth, #MedicalScience, #HealthEducation, #MythBusting Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 📕 Chapters (0:00) Introduction - How to choose a supplement that works (0:41) Why preclinical studies are so important (4:27) The combination that creates gold standard results (8:14) How the LOAM preclinical study actually worked (11:44) Surprising results from the LOAM trials (14:02) The importance of the short-chain fatty acid propionate (17:43) Why LOAM produces results so quickly (20:02) Why supplements don’t impact all people the same (22:18) How LOAM produces less gas than other fibre supplements (25:36) Fibre fermentation💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=spotify&utm_medium=podcast&utm_campaign=podcast_loam_clinical_trials 🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 🤖 Discover my digital twin here: http://DrKaran.ai 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe 🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5 🎙️ An OG Podcasts production. About Dr Karan: Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health. 📱Connect with me: Instagram: https://www.instagram.com/drkaranrajan/ Facebook: https://www.facebook.com/DrKaranR/ TikTok: https://www.tiktok.com/@dr.karanr X: https://twitter.com/drkaranrajan Website: https://linktr.ee/ThisisVitalInformation
April 20 · 53 min
The Secret To Reducing Arthritis in 8 Weeks...
Sleepwalking into arthritis isn’t inevitable. And some changes can show up faster than most people expect. In this episode, Dr Karan Rajan speaks with Professor Tamiko Katsumoto about why arthritis rates are rising, the differences between rheumatoid arthritis and osteoarthritis, and what the best evidence says about reducing joint inflammation, including a lifestyle medicine intervention where benefits were seen as early as 8 weeks (with the primary endpoint at 16 weeks). This isn’t about “miracle cures.” It’s about stacking the odds in your favour: Diet quality, fibre, fermented foods, weight and metabolic health, sleep, stress, movement. And how these interact with inflammation, the gut, and joint symptoms. In this episode, we cover: ∙ RA vs OA: Classic symptom patterns and why they’re treated differently ∙ Why treatments for osteoarthritis can feel limited (and why lifestyle is still worth discussing) ∙ “Food as medicine” and why joints are a symptom you can actually feel change ∙ The “Plants for Joints” study: What changed at 8 weeks and what the 16-week endpoint showed ∙ The gut-joint axis: Gut barrier, microbial diversity, and immune regulation ∙ Why some patients flare on ultra high meat / fibre-free approaches (and what to do instead) ∙ Practical “build my plate” guidance for joint and inflammation support #Arthritis #JointPain #RheumatoidArthritis #Osteoarthritis #Inflammation 💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10. 💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe 🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com 📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook 📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation 🤖 Discover my digital twin here: http://DrKaran.ai 🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlist About Dr Karan: Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health. 📱Connect with me: Instagram: / drkaranrajan Facebook: / drkaranr TikTok: / dr.karanr X: / drkaranrajan Website: www.drkaranrajan.com
April 16 · 36 min
How To Really Strengthen Your Pelvic Floor | Dr. Kelly (Peterson) Luithly
💬 One majorly overlooked part of health is your pelvic floor. You may think it’s just a worry for women - but men need to train their pelvic muscles too. The question is, how? If you’re the type of person who spends a lot of time sitting all day, have ever experienced gut problems or back pain - or you just want to improve your physique - this one’s for you. ⚡Dr Kelly Peterson is the master of pelvic floor exercises - and shares all her best techniques in this episode. 🎧 Stay tuned to find out: ➡ The 3 types of people who need to work on their pelvic floor ➡︎ What the pelvic floor is actually doing day-to-day ➡︎ The difference between a weak and an overactive pelvic floor ➡︎ Why holding in your pee - and forcing out your poop - are big no-nos ➡︎ The exercises you can do - anywhere! - to strengthen your pelvic floor daily #DrKaran, #PelvicFloor, #PoopHealth, #GutHealth, #BackPain, #BreathingTechniques, #WomensHealth, #MensHealth, #MedicalScience, #HealthEducation, #MythBusting Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 📕 Chapters (0:00) Introduction (0:31) How do you train your pelvic floor? (2:47) What does the pelvic floor actually do day-to-day? (4:56) Difference between weak and overactive pelvic floor (9:03) Common pelvic floor problems in men (12:30) Big no-nos when you go for a poop (16:14) Breathing techniques to use on the loo (20:59) Should you worry about making sounds while on the toilet? (23:02) How to potty train kids and turn them into super poopers (28:34) Why you shouldn't pee ‘just in case’ (31:05) Tips to improve your pelvic floor - wherever you are (33:29) How often should we do pelvic floor exercises? 🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 🤖 Discover my digital twin here: http://DrKaran.ai 🔥 Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10. 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe 🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share&ltsid=472cbbde-00e2-42ab-8a3f-725656fab3a5 🎙️ An OG Podcasts production. About Dr Karan: Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health. 📱Connect with me: Instagram: https://www.instagram.com/drkaranrajan/ Facebook: https://www.facebook.com/DrKaranR/ TikTok: https://www.tiktok.com/@dr.karanr X: https://twitter.com/drkaranrajan Website: https://linktr.ee/ThisisVitalInformation
April 13 · 43 min
The Menopause Symptoms We Keep Missing | Dr Louise Newson
Most people can’t name five menopause symptoms beyond hot flushes and the biggest problem might start with the word itself. In this episode, Dr Karan Rajan speaks with Dr Louise Newson, a hormone and menopause specialist, about what’s actually happening biologically, why symptoms get missed or mislabelled, and how evidence, guidelines, and real-world prescribing shape care. In this conversation, we cover: Why “menopause” as a label can obscure the underlying hormone biology The three-hormone framework: Oestrogen, progesterone, testosterone Why symptoms like brain fog, mood changes, and gut symptoms can be misattributed Bioidentical vs synthetic hormones (and why molecular structure matters) Osteoporosis risk, prevention, and what “healthy ageing” should include Dosing and absorption: Patches vs gels, and why some people need higher doses Why “guidelines” are a guide and where personalisation matters most 🎬 Chapters 01:22 – Most people can’t name five symptoms beyond hot flushes 01:56 – The definition problem: “A year without a period” doesn’t explain biology 02:59 – Back to basics: oestrogen, progesterone, testosterone 04:24 – Is menopause “just ageing” or a treatable deficiency state? 06:21 – Misdiagnosis: IBS, brain fog, depression and missed hormone deficiency 08:40 – Why “hard to measure” symptoms got ignored in research and guidelines 09:04 – Hormones and inflammation: metabolic risk shifts in perimenopause 10:32 – Osteoporosis risk and prevention: Why this matters clinically 11:22 – Sponsor: Loam 12:14 – Bioidentical vs synthetic hormones: The “key and lock” explanation 14:59 – Contraindications and breast cancer conversations 17:12 – Guidelines vs optimisation: Why safe does not always mean best 18:31 – How to read guidelines: Who wrote them, conflicts, and cited studies 20:18 – Dosing: “lowest effective dose” and why needs vary 22:25 – Louise’s own dosing story: Symptom improvement within days 24:14 – Absorption science: Skin variation and patch placement differences 26:01 – When to consider hormones: Symptoms and quality-of-life impact 27:18 – PMS and PMDD: Severe pre-period symptoms and hormone strategies 28:58 – The timing hypothesis and what WHI got wrong 31:04 – The “stop at 60” myth, synthetic-hormone data, and fear headlines 32:26 – The risks of not taking hormones 34:07 – Sponsor: Throne 35:11 – Gut microbiome and hormones: Reflux, bloating, and symptom shifts 41:29 – Outcomes and personalisation: The metric is quality of life 42:15 – Mental health outcomes discussion and clinic data 💩 Head to https://loamscience.com/products/loam-prebiotic-fiber-formula?utm_source=youtube&utm_medium=social&utm_campaign=drkaranexplores to try LOAM - and get an additional 10% with code POD10. 💊 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe 🚽 Discover Throne's incredible new smart toilet device at http://thronescience.com 📘 For more useful science for your everyday life, grab my best selling book "This Book May Save Your Life": https://geni.us/DrKaranBook 📕 Get my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation 🤖 Discover my digital twin here: http://DrKaran.ai 🧬 Sign up for my Microbiome Course waitlist: https://drkaran.kit.com/microbiome-course-waitlistAbout Dr Karan:Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humour. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.📱Connect with me:Instagram: / drkaranrajanFacebook: / drkaranrTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com

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