Authentic Biochemistry

Dr Daniel J. Guerra

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1,269 episodes
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Episodes1269

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Mar 21, 2022 · 29 min
Diabetes XVIII. Myokine mediated muscle mass signaling is corrupted by obesity linked Type 2 diabetes via massive inflammation and dyslipidaemia.DJGPhD. 21.3.22. Authentic Biochemistry
References Dr. Guerra's lecture notes J Immunol. 2018 Nov 15;201(10):2934-2946 Endocr Rev. 2020 Aug; 41(4): 594–609.
Mar 21, 2022 · 29 min
Diabetes XVII. Short and medium chain fatty acid derived ketones and skeletal muscle Myokines to improve cognitive and homeostatic well-being in humans. DJGPhD. 20.3.22 Authentic Biochemistry.
References Dr Guerra lecture notes Endocr Rev. 2020 Aug; 41(4): 594–609 Alzheimer’s & Dementia: Translational Research & Clinical Interventions (TRCI) 2021 Volume7, Issue1 e12217
Mar 19, 2022 · 29 min
Diabetes XVI. Fornix white matter fascicular region of the hippocampus nuclei is spared from neurodegeneration by dietary medium chain saturated fatty acid. DJGPhD.Authentic Biochemistry19.3.22
References Dr Guerra's Lecture notes Alzheimer’s & Dementia: Translational Research & Clinical Interventions (TRCI) Volume7, Issue1 2021 e12217
Mar 17, 2022 · 29 min
Diabetes XIV. The Neuropsychiatric/Neurodegeneration axis from Sphingomyelin Degeneration to Increased Inflammation. Dr. Daniel J. Guerra. 17.3.22. Authentic Biochemistry Productions
References Dr Guerra Lecture archives Alzheimer’s & Dementia: Translational Research & Clinical Interventions (TRCI) 2021.Volume7, Issue1 e12217 EBioMedicine. 2015 Dec; 2(12): 1888–1904
Mar 16, 2022 · 29 min
Diabetes XII. Free fatty acid dyslipidaemia associated dysregulation of hepatic and skeletal muscle Insulin Receptor Substrate (IRS)1/2 axis. Dr. Daniel J. Guerra15.3.22. Authentic Biochemistry .
References Dr. Guerra's lecture notes Curr Med Chem. 2017;24(17):1827-1852 Journal of Hepatology 2012 56, 704-713DOI: (10.1016/j.jhep.2011.09.020)
Mar 14, 2022 · 29 min
Diabetes XI. Biometrics in research interpretation. Dr Dan Guerra 14.3.22 Authentic Biochemistry.
Reference George A, Stead T S, Ganti L (August 26, 2020) What’s the Risk: Differentiating Risk Ratios, Odds Ratios, and Hazard Ratios?. Cureus12(8): e10047. doi:10.7759/cureus.10047.
Mar 8, 2022 · 29 min
Diabetes IX. The role of peroxisomes in ether-linked lipid biosynthesis. Dr.Daniel J. Guerra. 07March2022. Authentic Biochemistry Podcast production
References Dr Guerra's lecture material
Mar 5, 2022 · 30 min
DiabetesVIII. Subcellular organization and the role of lipid metabolism in mitochondria and peroxisomes. Dr Daniel J. Guerra. 05March22. Authentic Biochemistry
From Dr. Guerra's lecture archives
Mar 4, 2022 · 29 min
Diabetes VII. Cholangiocarcinomas and the corruption of the biliary system as sequalae of obesity and associated pancreatic exocrine insufficiency of diabetes. Dr Dan Guerra. 3.March.2022. A.B.
References Dr Guerra's lecture notes World J Gastroenterol. 2013 Nov 14; 19(42): 7258–7266. Int J Endocrinol. 2015; 2015: 595649. PLoS One. 2017; 12(10): e0186643. BMC Cancer. 2019; 19: 185
Mar 2, 2022 · 30 min
Diabetes V . PEI and Diabetic Dyslipidaemia with Primary Cholagiocarcinoma. Primer on lipid digestion and Lipoprotein Trafficking. Dr. Dan Guerra. Authentic Biochemistry 01.March.2022
References Dr. Guerra lecture notes BMC Cancer. 2019; 19: 185.
Mar 1, 2022 · 29 min
Diabetes IV. Pancreatic Exocrine Insufficiency in Types I, II, and III Diabetes Mellitus. Dr DAniel J. Guerra. 28.2.22. Authentic Biochemistry
References Dr. Guerra Lecture notes Int J Endocrinol. 2015; 595649
Feb 26, 2022 · 29 min
Diabetes III. Sphingosine 1-Phosphate in glioblastoma and prostagladin E2/EP4 in diabetic nephropathy-an axis of angiogenesis. Dr. Daniel J. Guerra. 25.2.22 Authentic Biochemistry
References Journal of Biological Chemistry.2013. 288 Issue 52 Pages 37355-37364. Prostaglandins & Other Lipid Mediators. 2022(April) . Volume 159, 106621
Feb 24, 2022 · 29 min
Diabetes II. The Insulin resistance factor and glucose intoxication associated dyslipidaemia and introduction to diabetic nephropathy. DJGPhD. 23.2.22. Authentic Biochemistry Podcast.
References Dr. Guerra's lecture notes Prostaglandins & Other Lipid Mediators 2022.April. 159. 106621 Reviews in Endocrine and Metabolic Disorders. 2020. 21: 631–643
Feb 23, 2022 · 29 min
Type 2 Diabetes I. Initial lecture describing insulin resistance and dyslipidaemia. Dr Daniel J. Guerra 22.2.22 Authentic Biochemistry Podcast.
References Dr. Guerra lecture notes Reviews in Endocrine and Metabolic Disorders. 2020. 21: 631–643. J Lipid Res. 2015 Mar; 56(3): 588–598.
Feb 18, 2022 · 30 min
Fatty Acids IX. The Monounsaturated fatty acid inhibition of ferroptosis and apoptosis leads to cancer progression. Pharmacotherapeutic Considerations. Dr Daniel J. Guerra. 17.2.22 Authentic Biochem.
References Dr. Guerra's notes-unpublished Cancer Res. 2019 Oct 15; 79(20): 5355–5366.
Feb 16, 2022 · 29 min
Fatty Acids VIII. The Potential for Ferroptosis enhancement via inhibition of Stearoyl CoA Desaturase as pharmacotherapy in Pancreatic Ductal Carcinoma.DJGPhD.16.2.22. Authentic Biochemistry.
References Redox Biol. 2021 Jan; 38: 101807 Cancer Res. 2019 Oct 15; 79(20): 5355–5366.
Feb 12, 2022 · 29 min
Fatty Acids VII. Stearoyl CoA Desaturase biochemistry and assocation with immune and metabolic disease. Dr Dan Guerra
References Dr Guerra Lecture notes Chem Biol Interact. 2019 Dec 12; 316: 108917 Chapter 7. Cook and McMaster. 2002. in Biochemistry of lipids, lipoproteins and membranes 4th edition. Elsevier Science. Vance and Vance eds.
Feb 11, 2022 · 26 min
Fatty Acids VI. The Inflammasome paradigm and transcription factor-mediated cytokine production as result of high carbohydrate diet and obesity. Dr. Daniel J. Guerra. 10.Feb 2022. Authentic Bichem.
References Chem Biol Interact. 2019 Dec 12; 316: 108917 J Neuroinflammation. 2019; 16: 236.
Feb 10, 2022 · 29 min
Fatty Acids V. Ketogenesis as a therapeutic to redistribute preserved Heart Failure cardiac ejection fraction via blockage of mitochondrial protein hyperactylation. DJGPhD.9FEB22. Authentic Biochem.
References Circulation Research 2020.Volume: 128, Issue: 2, Pages: 232-245, DOI: (10.1161/CIRCRESAHA.120.317933) J Neuroinflammation. 2019; 16: 236.
Feb 8, 2022 · 29 min
Fatty Acids IV. Adipocyte lipases and the Diacylglycerol PKC/PKD circuit of cellular degeneration leading to chronic inflammation-associated obesity. DJGPhD.07.Feb.22. Authentic Biochemistry
References Adv Exp Med Biol . 2017;960:135-160. Lipids in Health and Disease volume 19, Article number: 113 (2020) Circulation Research. 2020.Volume: 128, Issue: 2, Pages: 232-245