Authentic Biochemistry

Dr Daniel J. Guerra

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1,269 episodes
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Episodes1269

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Apr 25, 2022 · 29 min
Cytoepigenetics II. The First Principle of Biochemical Epigenetics and the dialectic of methylated promoter region PPAR-gamma and peroxisomal mitigation between rodent and human. DJGPhD.24.4.22
References Dr Guerra's ideas and concepts Cells. 2021 Jun; 10(6): 1355. Cells. 2019 Mar; 8(3): 227.
Apr 23, 2022 · 29 min
CytoEpigenetics I. Introduction. Dr. Daniel J. Guerra . 22.4.22. Authentic Biochemistry Podcast Productions
References Introductory remarks from Guerra's research Trends in Cell Biology, 2017-06-01, Volume 27, Issue 6, Pages 453-463.
Apr 20, 2022 · 29 min
Authentic Biochemistry is moving to a remote geographical region but will do so seamlessly and with full dedication. Please SUBSCRIBE and take notice of the discussion I have recorded here. DJGPhD
Dr Guerra takes this episode to redouble the committment of Authentic Biochemistry to providea detailed analysis and synthesis of current biomedical research science based on peer-reviewed published literature. Please become a regular subscriber! Grazie!
Apr 20, 2022 · 29 min
Diabetes XXXVI. Coda. Final lecture in diabetic dyslipidaemia.
References Dr. Guerra lipid lectures Journal of Diabetes Research, 2016, Article ID 2372741, 12 pages Lipids in Health and Disease 2013.12(1):98 Cell Reports 2022. 38, 110566
Apr 19, 2022 · 29 min
Diabetes XXXV. Rodent model adipose mitochondrial respiratory contribution to obesity control involves a selenium protein and UCP1 sulfenylation. Dr Daniel J. Guerra. Authentic Biochemistry.18.4.22
References Dr. Guerra Lipid and Intermediary Metabolism lectures Cell Reports 2022. 38, 110566 PNAS July 24, 2017 | 114 (32) 8649-8654
Apr 18, 2022 · 30 min
Diabetes XXXIV. White vs brown adipocytes and the role of transcription factors and metabolic enzyme expression to mediate bioenergetics vs.lipogenesis in store depot fat.DJGPhD.17.4.22. Authentic B.
References Dr. Guerra's lipid lecture archives PNAS July 24, 2017 | 114 (32) 8649-8654 Int J Mol Sci. 2019 Oct; 20(19): 4924
Apr 16, 2022 · 29 min
Diabetes XXXIII. Synthesis of lecture arc Part 2. Dr Daniel J. Guerra. Authentic Biochemistry Podcast Studios. 16.4.22
References Dr. Guerra's notes
Apr 15, 2022 · 29 min
Diabetes XXXII. Fatty acid oxygenation and use of eicosanoid molecular species to regulate T2D-linked inflammation via the agonization of the nuclear receptor transcription factor PPAR.DJGPhD 15.4.22
References Dr Guerra lipid lecture notes Biophysical J. Volume 110, Issue 11, 7 June 2016, Pages 2397-2406 Am J Pathol. 2020 Sep; 190(9): 1782–1788
Apr 14, 2022 · 29 min
Diabetes XXXI. REDOX biochemistry mini-review and the roles of essential fatty acid elongation/desaturation metabolism and COX/LOX oxygenation as ligands for PPAR isoforms in T2D pharmacotherapy.
References Dr. Guerra lecture material Nutr J. 2014; 13: 17.
Apr 13, 2022 · 29 min
Diabetes XXX. The pleitropic roles of free fatty acids and PPAR's as mediating insulin sensitivity, intermediary metabolism and the inflammatory response in T2D.Dr Daniel J. Guerra 13.4.22. Authentic
References Dr. Guerra lecture notes Prog Neurobiol. 2018 Apr-May; 163-164: 27–58. Arteriosclerosis, Thrombosis, and Vascular Biology. 2006;26:28–40
Apr 12, 2022 · 29 min
DiabetesXXIX. THe CNS axis of Obesity-linked T2D via alterations in PPAR transcription factor mediated expression of ameliorative hippocampal AMPAR and LTP neural transmission in Alzheimer's Discsease
References Dr. Guerra's Lecture Notes Journal of the American College of Nutrition. 2019. 38:8, 693-702. Curr Diabetes Rev. 2020;16(8):797-806
Apr 8, 2022 · 30 min
Diabetes XXVIII. Diabetic nephropathy is a consequence of non-esterified free fatty acid associated ceramide induction of the IRS-1 phosphorylation in glomerular podocytes inducing inflammation
References Dr Guerra lecture notes Front. Endocrinol., 14 October 2014. Sci Rep. 2020; 10: 21628.
Apr 7, 2022 · 29 min
Diabetes XXVII. Dyslipidaemia and the Insulin Resistance Axis. Dr. Daniel J. Guerra. Authentic Biochemistry Podcast 7April2022.
References Dr. Guerra's lectures Curr Med Chem. 2017;24(17):1827-1852 Cancer Res. 2018 Apr 1; 78(7): 1713–1725
Apr 5, 2022 · 29 min
Diabetes XXVI. Adipogenic and hypertrophic adiposity differentially control dyslipidaemia and Insulin resistance in association with pro-inflammatory cytokine induced T2D and breast cancer.DJGPhD.
References Dr. Guerra's lipid lecture notes Cancer Res. 2018 Apr 1; 78(7): 1713–1725. Progress in Lipid Research Volume 74, April 2019, Pages 145-159
Apr 2, 2022 · 29 min
Diabetes XXIV. Sphingosine 1-phosphate targeting and the abalation of primary breast cancer metastasis: IL6 mediated tumorigenesis blockade? Dr Daniel J. Guerra 01April2022. Authentic Bbiochemistry
References Dr Guerra's notes Front. Physiol., 30 January 2019 | https://doi.org/10.3389/fphys.2019.00042
Apr 1, 2022 · 29 min
Diabetes XXIII. Obesity-associated IL6 and sphingosine 1-phosphate are linked to breast cancer.Dr. Daniel J. Guerra. 31 March 2022. Authentic Biochemstry
References Dr. Guerra's lecture notes Front. Physiol., 30 January 2019 | https://doi.org/10.3389/fphys.2019.00042 Cold Spring Harb PerspectBiol. 2018 Feb; 10(2): a028415.
Mar 31, 2022 · 29 min
Diabetes XXII. Obesity and cancer are linked by inflammation and dyslipidaemia. Dr Daniel J. Guerra. 30.3.22 Authentic Biochemistry
References Dr Guerra's lectures notes Cancer Res. 2018 Apr 1; 78(7): 1713–1725 Cold Spring Harb PerspectBiol. 2018 Feb; 10(2): a028415.
Mar 28, 2022 · 29 min
Diabetes XXI. TAG accumulation in skeletal muscle of diabetics vs athletes and suggested role of Intramuscular TAG in Insulin Resistance due to subcelluar localization of lipid droplets. DJGPhD.27.3
References Dr Guerra's lecture notes Diabetologia. 2021 Jan; 64(1): 168–180 Diabetologia. 2020 Dec;63(12):2654-2664
Mar 25, 2022 · 29 min
Diabetes XX. Intermediary metabolic allosteric regulation in the Myocardial Infarcted heart reveals HF aetiology from obesity-linked Type 2 Diabetes. DJGPhD.25.3.22. Authentic Biochemistry Production
References Dr. Guerra lecture notes J AM Coll Cardiology Basic Trans Science.2019. (4) 3: 385-400
Mar 22, 2022 · 29 min
Diabetes XIX. THe ketogenesis bioenergetic system can be corrupted via DAG-kinase mediated pyroptosis in the obese/T2D CNS. Dr. Dan Guerra. 22.3.22. Authentic Biochemistry Podcast
References Dr. Guerra lecture notes Circulation Research Volume 128, Issue 10, 14 May 2021; Pages 1419-1420 Adv Exp Med Biol . 2017;960:135-160. Current Opinion in Clinical Nutrition and Metabolic Care Issue: Volume 21(4), July 2018, p 260-266