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  • Research To Practice | Oncology Videos

    Antibody-Drug Conjugates for Multiple Myeloma — An Interview with Dr Douglas W Sborov (Companion Faculty Lecture)

    Featuring a slide presentation and related discussion from Dr Douglas W Sborov, including the following topics: Overview of the treatment landscape for early relapsed multiple myeloma (MM) (0:00) Belantamab mafodotin (belamaf) mechanism of action and Phase II DREAMM-2 study of belamaf monotherapy in heavily pretreated MM (6:20) DREAMM-7 and DREAMM-8 Phase III trials of belamaf combination strategies in patients with MM in the second- and later-line settings (9:20) Monitoring for and management of belamaf-related ocular toxicities (12:29) Phase I DREAMM-9 trial of belamaf in combination with bortezomib/lenalidomide/dexamethasone (RVd) for transplant-ineligible newly diagnosed MM (16:23) Ongoing trials evaluating alternative belamaf dosing; practical considerations and recommendations for the administration of belamaf (19:07) CME information and select publications

    Yesterday · 23 min· Video
  • Research To Practice | Oncology Videos

    Antibody-Drug Conjugates for Multiple Myeloma — An Interview with Dr Douglas W Sborov

    Featuring an interview with Dr Douglas W Sborov, including the following topics: DREAMM-2 trial outcomes and clinical development of antibody-drug conjugates for multiple myeloma (MM); mechanism of action of belantamab mafodotin (belamaf) and predictors of response to treatment (0:00) Perspectives on findings from the Phase III DREAMM-7 trial of belamaf combined with bortezomib/dexamethasone for relapsed/refractory MM (4:26) Progression-free survival estimates with current quadruplet induction and maintenance regimens for newly diagnosed MM (6:36) Phase I DREAMM-9 trial and ongoing evaluation of belamaf in the up-front setting (11:48) Potential integration of belamaf into the relapsed/refractory and newly diagnosed MM treatment settings (16:00) Prevention and management of ophthalmic events related to treatment with belamaf (21:27) Case: A man in his mid 60s with multiregimen-recurrent MM receives single-agent belamaf (27:49) Case: A woman in her early 70s with recurrent t(11;14) MM and disease progression on single-agent belamaf experiences a sustained response to talquetamab (33:27) Case: A man in his early 70s with heavily pretreated MM receives belamaf with bortezomib (39:53) CME information and select publications

    Yesterday · 49 min· Video
  • Research To Practice | Oncology Videos

    Metastatic Triple-Negative Breast Cancer — 5-Minute Journal Club Activity 2 with Dr David W Cescon

    Featuring perspectives from Dr David W Cescon, including the following topics: Clinical treatment of BRCA-mutated metastatic triple-negative breast cancer (0:00) CNS activity of TROP2-directed antibody-drug conjugates (5:36) Autoimmune considerations with immunotherapy (10:09) Treatment of oligoprogressive advanced breast cancer (17:31) CME information and select publications

    Tuesday · 23 min· Video
  • Secrets Not Included

    Erst der Prozess, dann Renovate /PinUp – Der Weg zu Images ohne bekannte Lücken

    "Zero CVE" klingt gut auf der Landingpage – aber was steckt dahinter? Ole erklärt Daniel, wie sein Setup aus Trivy-Scans, Renovate / PinUp und selbstgebauten Paketen dafür sorgt, dass Critical- und High-Findings in Stunden statt Wochen wieder verschwinden. 4.964 Merge Requests in sieben Tagen, Teamgröße: 1. Und warum Automatisierung trotzdem nie der erste Schritt sein darf.

    Tuesday · 41 min· Video

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