The Dr. Brighten Show

Dr. Jolene Brighten

Dr. Jolene Brighten, a best-selling author, board certified naturopathic endocrinologist, and women’s health expert, hosts The Dr. Brighten Show—a podcast dedicated to igniting transformative conversations in women’s health. Through candid interviews with leading experts, innovators, and thought-leaders, this show brings you groundbreaking research, personal stories, and practical tools to help you confidently navigate your body and hormones. It’s a fun, engaging, and insightful journey designed to empower you with tangible, science-backed insights, so you can live your best, most vibrant life.

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169 episodes
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Episodes169

Newest first

May 14 · 38 min
PCOS Has a New Name: What PMOS Means and What Still Hasn’t Changed
Why PCOS is being renamed to PMOS, what the new term actually means, and why better language alone won’t fix broken hormone care.
May 12 · 50 min
Why Perimenopause Hormone Therapy Can Make Symptoms Worse: Gut, Liver, Thyroid, and Toxin Factors | Pamela Langenderfer
Why PMDD can look completely different from woman to woman—and how hormones, histamine, inflammation, ADHD, and nervous system health may all play a role.
May 7 · 29 min
Why PMDD Treatment Fails: SSRIs for PMDD, Birth Control, and What Your Doctor May Be Missing
Why PMDD treatments like SSRIs and birth control help some women, worsen symptoms for others, and what may be missing.
May 5 · 28 min
PMDD Antihistamines: Why They May Help — and Why Histamine Isn't the Whole Story
Exploring the link between histamine and PMDD—and whether antihistamines could help reduce mood swings, anxiety, and inflammation.
April 30 · 31 min
High Insulin, Severe PMS, Fibroids & Postpartum Anxiety: Your Hormone AMA
Exploring how progesterone resistance develops in endometriosis, the role of inflammation, and whether GLP-1 therapies could offer a new path forward.
April 28 · 28 min
Could GLP-1s Help Endometriosis? The Progesterone Resistance Theory
Can GLP-1s improve progesterone resistance in endometriosis? Exploring inflammation, hormone signaling, and what early research suggests.
April 23 · 33 min
ADHD, Motherhood, and Invisible Overload
A raw look at ADHD in motherhood—how invisible mental load, hormone shifts, and PMDD create overwhelm, burnout, and brain fog.
April 21 · 1 hr 15 min
Perimenopause Sleep Hormones: Cynthia Thurlow on Why Rest Changes First
Why sleep is the first sign of hormonal shifts in perimenopause—and how progesterone, estrogen, stress, and lifestyle shape nightly recovery.
April 16 · 35 min
Fertility Protocol for Conception: Labs, Nutrition & Proven Strategies
A practical, science-based fertility protocol covering labs, nutrition, lifestyle, and environmental factors to support ovulation and improve conception outcomes.
April 14 · 1 hr 42 min
Dry Eye Relief: What’s Causing Your Dry, Gritty Eyes (and the Simple Routine That Helps) | Dr. Carly Rose
Why dry eye isn’t just about tears—how tear film imbalance, daily habits, and simple routines like lid hygiene and blinking can bring lasting relief.
April 9 · 30 min
What Is ADHD Masking? The Perimenopause ADHD Connection
Why ADHD masking stops working in perimenopause and how hormonal shifts expose hidden symptoms, burnout, and executive dysfunction in women.
April 7 · 47 min
Skin Aging Treatment and Skin Microbiome: What “Leaky Skin” Could Be Telling You About Inflammation, Hormones, and Healthy Aging | Kiran Krishnan
A deep dive into “leaky skin,” the skin microbiome, and how inflammation, hormones, and gut health influence aging and skin resilience.
April 2 · 29 min
Can Ozempic and GLP-1’s Help Treat Endometriosis
If you’ve been wondering whether Ozempic, semaglutide, tirzepatide, or other GLP-1 medications could help with endometriosis symptoms, chronic pelvic pain, adhesions, fatigue, or endo belly, you are not alone. More and more women with endometriosis are reporting that GLP-1 medications may be helping with symptoms that go far beyond weight loss, from lower inflammation and less pain to improved energy and better blood sugar stability. But what does the science actually say? In this episode of The Dr. Brighten Show, Dr. Jolene Brighten breaks down the emerging research and real-world clinical observations around GLP-1 receptor agonists and endometriosis, including what is currently known, what remains theoretical, and why this conversation may be one of the most important developments in women’s health right now. You’ll learn how GLP-1 medications like Ozempic (semaglutide), Wegovy, Mounjaro (tirzepatide), liraglutide, and exenatide may influence inflammatory signaling, fibrosis, metabolic dysfunction, and long-term cardiovascular risk in women living with endometriosis. This Episode Is Brought to You By This episode is brought to you by The Endometriosis Reset, my step-by-step program designed to help women address the full-body drivers of endometriosis symptoms, including inflammation, blood sugar instability, endo belly, fatigue, scar tissue support, and nervous system dysregulation. Inside the program, I walk you through clear protocols for nutrition, supplement timing and dosing, lifestyle support, and the conversations to have with your doctor so you can stop piecing together conflicting advice online. Learn more at http://drbrighten.com/endocourse EndoGlobal Group At EndoGlobal Group, a network of world-class endometriosis specialists comes together to provide comprehensive, multidisciplinary care for patients with complex endometriosis—offering advanced diagnostic mapping, complete excision surgery, and holistic support. Click here to learn more and schedule a free consultation https://drbrighten.com/endoglobal 👩🏻‍⚕️Follow Dr. Jolene Brighten: 💻 Website:⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.drbrighten.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/drjolenebrighten⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🎥 TikTok: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@drjolenebrighten⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🧵Threads: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.threads.net/@drjolenebrighten⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Grab my free hormone friendly recipes here! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drbrighten.com/hormonekit/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🎧 Subscribe to the Podcast: Apple: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://podcasts.apple.com/us/podcast/the-dr-brighten-show/id1786362161⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Spotify: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://open.spotify.com/show/5VWcYWJFzi3OnwidT25IXi?si=481df20ef0a6417⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ YouTube:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/@drjolenebrighten⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 👉 If you found this episode valuable, drop a comment below to tell us what you loved most, and share it with a friend! Let’s spread the knowledge. 💬 Learn more about your ad choices. Visit megaphone.fm/adchoices
March 31 · 1 hr 22 min
Birth Control for Endometriosis? Hormones, Progesterone Resistance, and What Doctors Aren’t Telling You
Experts break down birth control options for endometriosis, progesterone resistance, and why hormonal therapy doesn’t work the same for everyone.
March 26 · 30 min
The 10 Most Unusual Symptoms of Perimenopause (and What They Really Mean)
From itchy ears to electric shock sensations, uncover the surprising symptoms of perimenopause and the hormonal shifts driving them.
March 24 · 1 hr 10 min
Endometriosis Surgery: What Most Doctors Won’t Tell You
Top surgeons reveal what truly determines success in endometriosis surgery, from excision vs. ablation to hidden risks, recurrence myths, and recovery.
March 19 · 35 min
Natural Ways to Manage Endometriosis Beyond Surgery
Why endometriosis pain can persist after surgery and how inflammation, gut health, hormones, and the nervous system shape long-term symptom relief.
March 17 · 1 hr 7 min
Endometriosis Relief of Pain: Experts Explain Laparoscopy, Chronic Pelvic Pain, and Why So Many Women Are Still Suffering
Join leading surgeons to uncover the complex biology of endometriosis. Learn why scans often appear normal, how the nervous system amplifies chronic pelvic pain, and why a multidisciplinary approach—including excision laparoscopy and lifestyle changes—is the gold standard for long-term relief.
March 12 · 20 min
The Hidden Connection Between Estrogen and Histamine: Why Your Hormones Cause Inflammation
How the estrogen–histamine feedback loop can trigger migraines, period pain, anxiety, skin reactions, and systemic inflammation throughout the menstrual cycle.
March 10 · 1 hr 27 min
What Is Endometriosis? 4 Surgeons Explain the Symptoms, Misdiagnosis, and Whole-Body Impact
A deep dive into how endometriosis affects the immune system, hormones, gut health, and nervous system—and why symptoms go far beyond pelvic pain.