
Episode 75: The Screw Built from One Molecule
More than two thousand years ago, Archimedes designed a spiral that lifts water uphill by turning inside a cylinder. Farmers still use versions of it. Hydroelectric plants use larger ones as turbines. The principle is simple enough that it has survived almost unchanged. Now an international team has built a version that is one molecule long, a few millionths of a millimeter, and wired between two gold electrodes. When electric current passes through the spiral, the molecule rotates. Reverse the voltage and it rotates the other way. Once the rotation becomes continuous, the molecule conducts electricity up to a hundred times better than it does while sitting still. The paper, Current-Driven Molecular Machine with Rotation-Enhanced Conductance, was published in Nature on 22 October 2026. The molecule was synthesized by the group of Michael Pittelkow at the University of Copenhagen. The single-molecule experiments were performed by Oren Tal and Anil Kumar Singh at the Weizmann Institute of Science in Israel. Theoretical work came from Fabian Pauly’s group at the University of Augsburg, together with collaborators at the Niels Bohr Institute and Huazhong University. This is Strange Bites. Tonight the lecture is about an ancient machine rebuilt at the scale of a single molecule, and about a feedback loop in which the current that makes the screw turn also makes the screw a better conductor. Sources Nature paper: Current-Driven Molecular Machine with Rotation-Enhanced Conductance. Nature, 22 October 2026. DOI: 10.1038/s41586-026-11312-x https://www.nature.com/articles/s41586-026-11312-x University of Augsburg / EurekAlert press release, 22 October 2026: https://www.eurekalert.org/news-releases/1148951 ScienceDaily summary: https://www.sciencedaily.com/releases/2026/10/261030002940.htm Weizmann Institute of Science summary: https://www.weizmann.ca/news/archimedes-screw-the-molecular-version/


















