MS Living Well: Key Info from Multiple Sclerosis Experts

Barry Singer, MD

Barry Singer, MD, Director of The MS Center for Innovations in Care at Missouri Baptist Medical Center, interviews global expert guests about the latest treatments, innovations and tips for people living with multiple sclerosis.

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S8 · E6
September 22 · 34 min
Cancer Risk in MS
Few conversations in the MS clinic generate as much anxiety as the one about cancer. Disease-modifying therapy labels can carry explicit malignancy warnings, and patients understandably arrive asking whether the drug meant to protect their brain might be putting the rest of their body at risk. What often goes unsaid is the other half of the story: several medications now used in MS started out as cancer drugs. Rituximab was a cornerstone of treatment for B-cell lymphoma, and cladribine was first approved for hairy cell leukemia. The relationship between MS therapy and cancer runs in both directions, and the warning labels tell only one side of it. This episode works through what the evidence actually shows. We discuss the mechanisms behind cancer risk with common MS therapies and how a country that has tracked its entire MS population since 1956 can answer questions no three-year trial could. What do 34,000 patients followed for life reveal now that most are on high-efficacy therapy? The conversation also covers why absolute numbers change the discussion, which screenings belong on the calendar for different drug classes, and which symptoms are too easily written off as MS. We also explore why oncologists often advise staying on B-cell therapy after a cancer diagnosis and long-term data showing newly diagnosed patients keeping their mobility and their jobs far longer than the generation before them. Jameson Holloman MD, neurologist at The MS Center for Innovations in Care, interviews: Esther Melamed MD, PhD, Associate Professor of Neurology, and Associate Chair for Research in the Department of Neurology at Dell Medical School, University of Texas, Austin Melinda Magyar MD PhD, a senior consultant neurologist at the Danish Multiple Sclerosis Center at Rigshospitalet, Associate Professor of Neurology at the University of Copenhagen, and Director of the Danish Multiple Sclerosis Registry
S8 · E5
September 1 · 41 min
GLP-1s, Weight and Exercise in MS
Maintaining a healthy weight may be particularly important in multiple sclerosis, as excess fat tissue can promote inflammation and contribute to other health conditions that may complicate MS. GLP-1 medications such as Ozempic and Mounjaro have transformed weight management, but could their benefits extend beyond weight loss? We explore emerging evidence that these medications may reduce inflammation, protect nerve cells, and possibly promote myelin repair, as well as clinical trials investigating their potential impact on MS progression. Exercise can also do much more than build muscle. We explore how targeted movement may harness neuroplasticity—the brain's ability to adapt and find new pathways around areas damaged by MS. Practical strategies are shared for improving fatigue, spasticity, core strength, balance, and mobility, even for people with significant disability. Barry Singer MD, Director of The MS Center for Innovations in Care, interviews: Olaf Stuve MD PhD, Professor of Neurology and Head of the Multiple Sclerosis and Neuroimmunology Section. UT Southwestern Medical Center, Dallas, Texas Trevor Wicken, Founder of The MS Gym, a global online platform for exercise and mindset training for people living with multiple sclerosis
S8 · E4
July 21 · 39 min
Caregiving in MS
When multiple sclerosis enters a family, it doesn't just change the life of the person diagnosed. It reshapes the daily routines, roles, and futures of the people who love them. A spouse steps into new responsibilities, a child learns to help in ways their peers never will, and an entire household begins to adapt. These changes occur quietly, and often without recognition. Caregiving is one of the most essential pillars of the MS journey, and also one of the most invisible. This episode explores the caregiver experience from the inside out. We discuss why the uncertainty of MS can be one of the hardest parts of caregiving, how stepping into a care partner role can unexpectedly foster maturity, closeness, and personal growth, and why a caregiver's own well-being is inseparable from that of the person they support. The conversation also dives into practical tools for building resilience including Acceptance and Commitment Therapy, the READY for MS program, and the everyday strategies one husband relies on to stay connected to his wife as they navigate life with MS together. Jameson Holloman MD, neurologist at The MS Center for Innovations in Care, interviews: Kenneth Pakenham PhD, Emeritus Professor of Clinical and Health Psychology at the University of Queensland who pioneered the use of Acceptance and Commitment Therapy in chronic illness and developed the READY for MS resilience program. Dan Shaul, care partner to his wife, Kim, who lives with MS. An Air Force veteran and former Missouri state representative, he serves on the board of MS Bright Spots of Hope in St. Louis.
S8 · E3
June 30 · 43 min
Maintaining Employment with MS and Applying for Disability
Employment is about more than a paycheck. It can provide purpose, community, and independence. But MS symptoms like fatigue, cognitive changes, and mobility issues often raise difficult questions about whether to stay in a current job, request accommodations, or eventually consider disability benefits. In this episode of MS Living Well, we hear from two experts who help people navigate these complex decisions with employers and benefit agencies every day. The conversation covers how to stay in the workforce longer, when and how to disclose a diagnosis, the workplace accommodations people actually use most, and how to plan ahead for a disability claim including FMLA, private disability insurance, and Social Security Disability. Dr. Jamie Holloman, neurologist at the MS Center for Innovations in Care at Missouri Baptist Medical Center, interviews: Phillip Rumrill Phd, CRC, Professor at Michigan State University and a certified rehabilitation counselor with roughly 35 years of research on employment, vocational rehabilitation, and workplace accommodations for people with MS. Jamie R. Hall, Esquire, attorney and founder of the Law Office of Jamie R. Hall, who has focused on Social Security and long-term disability claims for 17 years and works extensively with the MS community.
S8 · E2
June 2 · 38 min
Beyond White Spots: Rethinking MRI in MS
MRI scans can reveal far more than just "white spots." New imaging techniques are uncovering hidden inflammation, silent disease activity, and smoldering lesions that may continue damaging the brain even when someone feels stable and routine MRI scans appear unchanged. This episode explores how MRI is evolving from a diagnostic tool into a window into the underlying biology of multiple sclerosis. We discuss why spinal cord imaging can sometimes reveal disease missed in the brain, how the "central vein sign" may help prevent MS misdiagnosis, and why brain shrinkage remains difficult to measure reliably in individuals living with multiple sclerosis. The conversation also dives into some of the most exciting frontiers in MS imaging including myelin repair, functional MRI, and how artificial intelligence could dramatically improve the speed and precision of MRI scans in the future. Barry Singer, MD, Director of The MS Center for Innovations in Care, interviews: Anthony Traboulsee, MD, Professor of Neurology, University of British Columbia and Director of the UBC MS/MRI Research Group in Vancouver Frederik Barkhof, MD, PhD, Professor of Neuroradiology, Amsterdam UMC and University College London
S8 · E1
May 12 · 40 min
Handling MS: Word-Finding and Memory Strategies
Cognitive changes are a common part of living with multiple sclerosis, but they can be confusing and frustrating. Many people feel like their memory is slipping, when in reality, the challenge is often with accessing information—especially in the moment. Forgetting why you walked into a room or struggling to find the right word in conversation are very real experiences in MS, and they're more about how the brain processes and retrieves information than a loss of intelligence or knowledge. New insights are helping us better understand why this happens, including the role of inflammation and how today's treatments may be helping keep cognition more stable over time. In this episode, Dr. James Sumowski breaks down what's happening in the brain, including why word-finding problems are so common and what "working memory" really means in everyday life. Speech-language pathologist Dr. Marissa Barrera then shares practical, easy-to-use strategies to support memory and communication from simple ways to make information more memorable, to talking around a missing word, and creating routines that reduce mental overload. Together, they offer both clarity and actionable tools to help you think more clearly, communicate more confidently, and navigate cognitive challenges day to day. Barry Singer, MD, Director of The MS Center for Innovations in Care, interviews: James F. Sumowski, PhD, Associate Professor of Neurology at the Icahn School of Medicine, Mount Sinai, New York Marissa Barrera, PhD, MSCS, CCC-SLP, Assistant Dean of Health Sciences, Katz School of Science and Health, Yeshiva University, New York
S7 · E8
Nov 18, 2025 · 36 min
The Science of MS Supplements
Many people living with multiple sclerosis are interested in whether vitamins, supplements, or nutrition can play a supportive role in long-term brain and immune health. Two areas that have received growing research attention are alpha-linolenic acid, a plant-based omega-3 fatty acid found in foods like flaxseed and walnuts, and vitamin D, a hormone-like nutrient involved in immune regulation that is often low in people with MS. With so much information online, it can be difficult to know what is truly supported by research versus what is based on personal stories or assumption. New studies are helping us understand these topics more clearly. We explore new insights from large-scale cohort studies and randomized clinical trials assessing the potential role of alpha-linolenic acid and high-dose vitamin D supplementation in early MS. Biomarker-based findings show an association between higher alpha-linolenic acid levels and reduced relapse risk and disability progression over long-term follow-up. The D-Lay MS trial demonstrated a reduction in disease activity in people living with MS receiving high-dose vitamin D early in their condition. Jamie Holloman MD, neurologist at The MS Center for Innovations in Care, interviews: Marianna Cortese MD PhD, Senior Research Scientist, Department of Nutrition at Harvard T.H. Chan School of Public Health Professor Éric Thouvenot, Head of the Neurology Department, Nîmes University Hospital, France
S7 · E7
Oct 14, 2025 · 44 min
Reengineering Hope: CAR-T Therapy for Multiple Sclerosis
CAR-T therapy, short for chimeric antigen receptor T-cell therapy, is already transforming treatment for blood cancers like lymphoma and leukemia and is now being tested in early trials for multiple sclerosis. In this approach, a person's own T cells (or sometimes donor T cells) are collected and reengineered in the lab with a special "chimeric" receptor on their surface. Once infused back into the body, these "designer" T cells can specifically hunt down B cells, including those hiding in the brain and spinal cord that may drive progressive MS. This is a key difference since current B-cell depleting antibody treatments don't reach effectively into the central nervous system. Like any powerful therapy, CAR-T is not without risks. Side effects can include serious infections, cytokine release syndrome (fever, chills, body aches), and even neurological symptoms like confusion or seizures. Still, the early results in MS patients are remarkable, bringing fresh hope for those with progressive disease. Beyond MS, CAR-T is being explored across autoimmune neurological diseases from myasthenia gravis to stiff person syndrome, opening a promising new frontier in care. Barry Singer MD, Director of the MS Center for Innovations in Care, interviews: Jeffrey Dunn MD, Clinical Professor and Chief of Neuroimmunology in the Department of Neurology & Neurological Sciences at Stanford University Amanda Piquet MD, Professor of Neurology and Céline Dion Foundation Endowed Chair at the University of Colorado Anschutz School of Medicine
S7 · E6
Sep 9, 2025 · 39 min
Repairing MS: The Quest to Rebuild Myelin
The quest to repair the damage caused by multiple sclerosis is gaining momentum, with scientists working to restore lost function and slow progression by rebuilding myelin—the protective coating of nerve cells. Within the brain and spinal cord, immature myelin-making cells called OPCs hold promise, but need the right signals to mature into oligodendrocytes and repair MS lesions. Researchers are also studying the role of microglia, the immune cells that clear debris but can turn destructive, with drugs like BTK inhibitors potentially tilting them toward repair. Early attempts at remyelination drugs such as opicinumab and elezanumab showed promise in animals but ultimately failed in human trials, underscoring the challenge. Still, reasons for optimism are emerging: clemastine, a common antihistamine, showed signs of remyelination in optic neuritis, while PIPE-307—a compound inspired by green mamba snake venom—is in Phase 2 trials. Even novel approaches like gold nanoparticles are being studied to boost oligodendrocyte energy and repair capacity. The path is complex, but progress is accelerating—bringing remyelination therapies closer to becoming a real option for people living with MS. Barry Singer MD, Director of The MS Center for Innovations in Care, interviews: Veronique Miron PhD, MS Research Chair at St. Michael's Hospital and Professor of Immunology at The University of Toronto Robert Glanzman MD, Board-certified neurologist and Chief Medical Officer of Find Therapeutics
S7 · E5
Aug 19, 2025 · 31 min
Parenting with MS: Finding Strength, Joy, and Resilience
Parenting can be both a beautiful adventure and a demanding test. For those living with multiple sclerosis, the joys of raising children often come with added challenges—fatigue, changes in routine, and questions about how MS may affect family life. Despite these obstacles, many parents with MS find that their journey brings deeper meaning, resilience, and joy. In this podcast episode, we'll explore the unique challenges and strengths of parenting with MS. From managing invisible symptoms to navigating conversations with children, our guests share their expertise and experience to provide guidance and encouragement for families. Dr. Jamie Holloman, neurologist at the MS Center for Innovations in Care at Missouri Baptist Medical Center, interviews: Amy Sullivan PsyD, Clinical Health Psychologist, Director of Behavioral Medicine at the Cleveland Clinic Mellen Center for Multiple Sclerosis. Julie Stamm, MS advocate and author of Some Days: A Tale of Love, Ice Cream, and My Mom's Chronic Illness.
S7 · E4
Jul 22, 2025 · 45 min
Repair, Reset, Reimagine: Stem Cell Therapies for Multiple Sclerosis
Stem cells have the extraordinary ability to transform into different types of cells and renew themselves—offering new hope in the treatment of multiple sclerosis. One of the most advanced approaches—autologous hematopoietic stem cell transplantation (AHSCT)—involves collecting a patient's own bone marrow stem cells, using chemotherapy to wipe out their faulty immune system, and then reinfusing the stem cells to help rebuild it. A more aggressive "myeloablative" approach can effectively halt relapses and new MRI activity but carries serious risks, including life-threatening infections. A gentler "immunoablative" method reduces these risks but allows for a return of MS activity in up to 25% of patients. AHSCT is typically reserved for younger individuals with aggressive relapsing disease and moderate or milder disability. Mesenchymal stem cells—derived from fat, bone marrow support tissue, or dental pulp—have shown mixed results. A large international trial found no benefit when delivered intravenously, although the treatment was safe. However, a smaller study using repeated injections into the spinal fluid showed disease stabilization in most participants. New research is now exploring neural stem cells, which may help protect and repair the brain and spinal cord. A recent Phase 1 trial involving 15 people with secondary progressive MS found reduced inflammation in blood and spinal fluid markers and less brain shrinkage on MRI scans following neural stem cells given into the spinal fluid spaces of the brain. Tune in as we unpack the science, the risks, and the exciting future of stem cell therapies in MS. Barry Singer MD, Director of The MS Center for Innovations in Care, interviews: Stefano Pluchino MD PhD, Clinical Professor of Regenerative Neuroimmunology, Honorary Consultant in Neurology, University of Cambridge, UK Mark Freedman MD, Professor of Medicine in the field of neurology, University of Ottawa, and Director of the Multiple Sclerosis Research Unit, Ottawa Hospital, Canada
S7 · E3
Jul 1, 2025 · 40 min
Beyond the Prescription Pad: Complementary and Alternative Medicine for MS
Most people living with multiple sclerosis explore complementary or alternative medicine (CAM) as part of their care. Complementary therapies—such as supplements, special diets, or mind-body practices—are used alongside disease-modifying treatments (DMTs), while alternative therapies are chosen instead of them. In this episode, we dive into commonly used CAM approaches, including anti-inflammatory and antioxidant supplements like turmeric and alpha-lipoic acid, as well as dietary strategies like the Mediterranean diet, intermittent fasting, and modified paleo. We also explore mind-body therapies—yoga, stretching, Pilates, and meditation—that may reduce stress, enhance well-being, and even lower inflammation. Plus, we examine alternative treatments such as low-dose naltrexone (LDN), CCSVI procedures, and hyperbaric oxygen therapy, along with the potential risks of bypassing conventional care. Thoughtfully chosen and openly discussed with your healthcare team, CAM can play a meaningful supportive role in living well with MS. Barry Singer MD, Director of The MS Center for Innovations in Care, interviews: Elizabeth Silbermann MD, MS Regional Director, VA Portland Health Care System and Assistant Professor of Neurology, Oregon Health and Science University. Daniel Bandari MD, Medical Director and the Founder of the Multiple Sclerosis Center of California Clinic and Research Group, Laguna Hills, Orange County, California and Clinical Assistant Professor of Neurology and Neuro-immunology, University of Southern California
S7 · E2
Jun 10, 2025 · 35 min
Boosting Brain Health: Blueprint for MS
Living with multiple sclerosis brings unique challenges to brain health, but there are powerful steps you can take to support and protect your mind. Exercise not only improves endurance and reduces fatigue, but also helps rewire brain networks to promote resilience. Restorative sleep is essential, as it helps clear inflammation in the brain—so addressing disrupted sleep is a must. Nourish yourself with fruits and vegetables while cutting out sugary drinks and highly processed meats. Strengthen your social connections and lean on your support circle. When it comes to managing stress, discover what works best for you, whether it's music, yoga, meditation, or a favorite hobby. MS can cause the brain to shrink faster than normal—a process called atrophy—so protecting your brain reserves is crucial. Starting with effective disease-modifying therapy is key, but it doesn't stop there. Keep your brain engaged by reading, learning a new language, or picking up an instrument. If you smoke, creating a plan to quit is one of the most important steps you can take to reduce physical and cognitive decline. While MS can be unpredictable, you have the power to shape your brain health and preserve what matters most. Barry Singer MD, Director of The MS Center for Innovations in Care, interviews: Lisa Doggett MD MPH, family and lifestyle medicine physician, UT Health Austin's Multiple Sclerosis and Neuroimmunology Center Augusto Miravalle MD, Professor and Chief of the Multiple Sclerosis Center, Rush University, Chicago
S7 · E1
May 20, 2025 · 37 min
Secondary Progressive MS: Next Chapter
Figuring out if your multiple sclerosis is changing from the relapsing remitting to the secondary progressive stage can be murky. Signs of progression are discussed like slower walking and worsening memory. The underlying reasons for progression are revealed including nervous system injury, remyelination failure, chronic inflammation and aging. Practical ways to improve progressive symptoms are shared. Successful trials for disease-modifying therapy for secondary progressive multiple sclerosis (SPMS) are highlighted. Tolebrutinib, under expedited review by the FDA, has been shown to slow down progression in SPMS patients by targeting cells in the central nervous system causing chronic inflammation. Introducing our new co-host Jamie Holloman MD from The MS Center for Innovations in Care! Dr. Holloman completed in neurology residency at Washington University, followed by a 3-year fellowship at the Cleveland Clinic. He interviews: Christopher Laganke MD, Founder of the Joanne P. LaGanke MS Center, Cullman, Alabama Barry Singer MD, Director of The MS Center for Innovations in Care, Missouri Baptist Medical Center, St. Louis
S6 · E8
Oct 1, 2024 · 38 min
Mind Over MS: Strategies for Staying Positive
Facing the first symptoms and a new multiple sclerosis diagnosis can be terrifying, leaving you with a flood of questions about your future. How do you navigate your career, relationships, and whether to start a family? The uncertainty can be overwhelming, but you don't have to go it alone. Support from loved ones and connections with others living with MS can help light the way. As MS progresses, the mental challenges often intensify. The battle to accept mobility aids—devices that many resist—can feel like a loss, but in reality, they can expand your world. In this episode, we dive deep into the mental strategies to better cope with MS. Two inspiring advocates living with MS describe embracing change, turning their struggles into stories of strength, adaptability and hope. Barry Singer MD, Director of The MS Center for Innovations in Care, interviews: Ardra Shephard, writer, podcaster and television host based in Toronto, Canada Tyler Campbell, professional inspirational speaker and former college football player from Austin, Texas
S6 · E7
Sep 10, 2024 · 35 min
Diagnosing Multiple Sclerosis
In this era of highly effective treatments, early intervention for multiple sclerosis can be life changing. However, the wide range of initial symptoms often leads to many people being undiagnosed or misdiagnosed, leaving them without the proper care for years. In this podcast episode, we'll discuss the early signs of MS and the key tests, such as specific MRI and spinal fluid results, that are crucial for a timely and accurate diagnosis. Criteria to diagnose MS continues to evolve to help make a diagnosis more swiftly and correctly. Specific MRI findings in the brain and spinal cord can allow for an immediate diagnosis of MS with the first attack. Brand-new updates highlight the role of the optic nerve and even offer a path to diagnosing MS in people who show no neurological symptoms. With so much at stake, a timely and accurate diagnosis of MS is more important than ever. Barry Singer MD, Director of The MS Center for Innovations in Care, interviews: Xavier Montalban MD PhD, Chair of Neurology, Director of CEMCAT (Multiple Sclerosis Center of Catalonia) at Vall d'Hebron University Hospital, Barcelona, Spain Léorah Freeman MD PhD, Assistant Professor, Dell Medical School Department of Neurology, UT Health Austin Multiple Sclerosis and Neuroimmunology Center
S6 · E6
Aug 20, 2024 · 39 min
MS & The Spinal Cord
The spinal cord serves as the main communication highway between the brain and body. Did you know that 80% of people with multiple sclerosis have spinal cord lesions on MRI? These lesions can disrupt specific neural pathways, leading to common MS symptoms like numbness, weakness, impaired coordination, balance issues, bladder problems, constipation, and sexual dysfunction. For instance, damage to the corticospinal tract on one side of the spinal cord can weaken an arm or leg. A remarkable autopsy study revealed that nearly 90% of people with MS still had active inflammation in the spinal cord. This finding brings new hope for potential treatments, even for older and progressive MS patients. Advances in imaging technology, including more powerful MRI scanners (3 Tesla and higher), are enhancing our ability to see inside the spinal cord, which is as thin as a pinky finger. Improved spinal cord imaging is driving the development of new therapies in clinical trials and helping identify those at risk for worsening disability, ultimately guiding better treatment decisions. Barry Singer MD, Director of The MS Center for Innovations in Care, interviews: Gabriele De Luca MD DPhil, Professor of Clinical Neurology and Experimental Neuropathology, University of Oxford, United Kingdom Bruce Cree MD PhD, Professor of Neurology at University of California, San Francisco School of Medicine
S6 · E5
May 7, 2024 · 35 min
Uncommon Multiple Sclerosis Symptoms
Awareness of the more uncommon multiple sclerosis symptoms can lead to an earlier diagnosis and appropriate treatment. For instance, experiencing electrical shock sensations when bending the neck forward, known as Lhermitte's sign, may indicate an attack on the cervical spinal cord. Likewise, excruciating bolts of pain across either side of the face, called trigeminal neuralgia, can be caused by a MS relapse. The MS hug, an unfriendly, squeezing sensation around the torso, can respond to muscle relaxants and nerve pain medications. Some MS symptoms, like tingling in legs, only surface when exercising or overheated (Uhthoff's phenomenon). Vertigo, a spinning sensation, can be a sign of MS, especially when lasting days and accompanied by other symptoms like gait imbalance, facial numbness and double vision. Brainstem attacks may also lead to swallowing issues and shaky vision. While MS bladder issues are commonly addressed, bowel problems, including constipation, urgency, incontinence and trouble evacuating, should not be overlooked. Overcoming stigma is essential to treat sexual dysfunction. Barry Singer MD, Director of The MS Center for Innovations in Care, interviews: Mary Ann Picone MD, Medical Director, MS Center at Holy Name Medical Center, Teaneck, New Jersey Bruce Hughes MD, Director of the Ruan Multiple Sclerosis Center, MercyOne, Des Moines, Iowa
S6 · E4
Apr 9, 2024 · 39 min
Harnessing AI: Transforming MS Care
Prepare to be intrigued by the groundbreaking intersection of artificial intelligence (AI) and multiple sclerosis care! By combing through extensive databases, including genetic information and real patient records, AI can forecast with remarkable accuracy the likelihood of MS onset. In the near future, AI could even serve as a guiding light for clinicians and MS patients in selecting the most suitable disease-modifying therapies, armed with predictive algorithms tailored for each individual. But the marvels of AI don't stop there. In a recent study, AI detected an astonishing 93% of new and enlarging T2 brain lesions in MRI scans, far surpassing the 58% accuracy rate of routine radiology reads. Artificial intelligence is also making waves in drug development and early clinical trial design, accelerating the quest for innovative therapies to combat MS. Barry Singer MD, Director of The MS Center for Innovations in Care, interviews: Tal Arbel PhD, Professor, Department of Electrical and Computer Engineering, McGill University, Montreal Michael Barnett MBBS (Hons) FRACP PhD, Professor in Neurology, University of Sydney and Director of the MS Society Clinic & MS Clinical Trials Unit at the Brain and Mind Centre
S6 · E3
Mar 19, 2024 · 42 min
Navigating MS with Other Medical Conditions
Living with multiple sclerosis isn't just about managing the condition itself, but often involves navigating a myriad of additional health concerns known as comorbidities. Individuals with MS face a higher risk of experiencing new relapses when dealing with comorbidities like high cholesterol or depression. Furthermore, autoimmune diseases such as psoriasis and inflammatory bowel diseases like Crohn's disease and ulcerative colitis are more prevalent among those with MS. There is even a heightened risk of bladder cancer. Interaction of MS treatments and other common conditions like high blood pressure (hypertension), high cholesterol and diabetes are addressed. Experts share how immunotherapies used for other autoimmune diseases may benefit or actually worsen MS disease activity. Crucial information is shared on cancer treatment concerns in individuals with MS. Adopting healthy lifestyle behaviors is essential to minimize the development of these comorbidities. Barry Singer MD, Director of The MS Center for Innovations in Care, interviews: Ruth Ann Marrie MD PhD, Professor of Medicine and Community Health Sciences at University of Manitoba, Canada Mark Cascione, MS neurologist, South Tampa MS Center, USA.

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