IBD Essentials

Axel Dignaß

We are dedicated IBD clinicians and researchers trying to bring you the latest updates in science and teaching of GI endoscopy. Host Axel Dignaß and his co-hosts Ailsa Hart, Iris Dotan and Florian Rieder speak with renown guest from all over the world. We are grateful to our sponsors abbvie, Falk Foundation e.V. and Olympus.

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20 episodes
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Avg 24 min
English

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Wednesday · 22 min
Pregnancy in IBD
Iris Dotan and Mette Julsgaard about Pregnancy in IBD
August 12 · 22 min
Special Aspects of IBD management in Japan, monitoring strategies and medical treatment in IBD patients
Taku Kobayashi from Tokyo talks about special aspects of IBD management in Japan, monitoring strategies and medical treatment in Japanese IBD patients including apheresis, tacrolimus, differences in the diseae course of Japanese and European patients with IBD and different managment strategies
July 29 · 25 min
The Stenova trial: A new treatment option with Ontunisertib in fibrostenosing CD
Florian Rieder from Cleveland Clinic, Cleveland, USA, internationally renowned IBD, intestinal fibrosis expert and principal investigator of the new treatment option with the oral GI-restricted small molecule inhibitor of ALK-5 Ontunisertib in fibrostenosisng CD
July 15 · 25 min
Special Aspects of IBD management in South America, Early Surgery in Crohn's disease and the emerging role of robotic surgery in IBD surgery
Paulo Kotze, Curtiba, Brazil, talks about special aspects of IBD management in South America, Early Surgery in Crohn's disease, appendectomy as a new treatment option in ulcerative colitis and the emerging role of robotic surgery in IBD surgery
July 1 · 22 min
Special Aspects of IBD management in the Middle-East and career pathways of women in GI and IBD
Dr. Sara El Ouali, UAE, talks about the rise of IBD in the mid-east, special aspects of IBD management in the Middle-East and career pathways of women in GI and IBD, including gender disparities, difficult career paths for women and barriers of women in their career and the importance of mentoring programs
June 24 · 24 min
Biography and credos of Jean-Fred Colombel and strategies for prevention and very early modification of IBD
Jean-Fred Colombel, Mount Sinai Hospital New York City, USA, talks about his biography and personal pathway in IBD and options of very early diagnosis of IBD and strategies to prevent the onset of IBD (interception) and early management of IBD
June 10 · 24 min
Biography of Bruce Sands and breaking the therapeutic ceiling in IBD
Bruce Sands, Mount Sinai Hospital New York City, USA, talks about his biography and personal pathway in IBD and options of breaking the therapeutic ceiling in IBD including combination therapy, treat to target and early treatment
May 27 · 24 min
Management of postoperative Crohn's disease
Matthieu Allez, Montreal, talks about the management of postoperative Crohn's disease, prediction of relapse rates, monitoring strategies in the postoperative setting, risk factors for postoperative recurrence and potential strategies to prevent recurrence
May 13 · 20 min
Recent BSGE guidelines of chromoendoscopy
Pradeep Bhandari from Portsmouth (UK) on recent BSGE guidelines of chromoendoscopy, co-hosted by Raf Bisschops.
April 29 · 23 min
Recent clinical trial results informing clinical decision making for vedolizumab and anti-IL23 therapies
Dr. Remo Panaccione, an internationally recognized expert in clinical trials discusses the recent data on vedolizumab and anti-IL23 therapies and how those changes impact clinical decision making in IBD
April 15 · 24 min
Relevance of cell-based therapies in IBD including hematopoetic stem cell transplantation and CAR T cell therapies
Matthieu Allez, Montreal talks about cell-based therapeutic approaches in refractory or complicated IBD covering hematopoetic stem cell transplantation and CAR T cell therapies, indication for this treatment options, success rates and potential side effects and potential future approaches
April 1 · 29 min
Discussion about the role of B cells in health and other autoimmune diseases with highlighting the recent groundbreaking observations of B cell directed CART cell therapy in IBD
Dr. Saurabh Mehandru, Mount Sinai Hospital in New York, internationally recognized physician scientist in IBD and global leader in B cell biology in intestinal health and inflammation discussed the role of B cells in intestinal homeostasis and IBD. Highliy relevant episode about a novel therapy that is entering IBD.
March 18 · 25 min
Introduction of Ailsa Hart as Co-Host of IBD Essentials and Management of Perianal Crohn's disease
Ailsa Hart, St. Marks Hospital, London, UK, internationally renowned IBD expert talks about strategies to optimize the management of perianal fistulising Crohn's disease, relevance of MDT approaches, building international consortia, classification and optimized management of perianal fistulising CD
March 4 · 23 min
Introduction of Florian Rieder as Co-Host of IBD Essentials and Fibrosis in IBD: A new target for evaluation and treatment
Florian Rieder from Cleveland Clinic, Cleveland, USA, internationally renowned IBD and intestinal fibrosis expert talks about his fundamental work and participation in intestinal fibrosis, spanning from basic research, clinical evaluation including establishing a fibrosis PRO, work on international consensus to evaluate intestinal fibrosis and new treatment options for intestinal fibrosis
February 18 · 25 min
How medical guidelines can improve the management of IBD
Andreas Sturm, gastroenterologist and IBDand medical guideline expert from Berlin, discusses about the development of evidence based guidelines and the relevance to improve the management of patients with IBD and the implementation of guidelines into clinical practice.
February 4 · 22 min
Why should students and junior doctors pursue a career in IBD and how can UEG help?
Paulo Sousa from Porto, current chair of the young talent group of UEG, reflects why she decided to become a gastroenterologist and to pursue a career in IBD. She describes how UEG may help tom foster a career in gastroenterology and why it may be useful to engage with UEG beyond UEGW
January 28 · 25 min
Emerging relevance of AI in the management of IBD
Thomas Rösch, editor of Endoscopy Essentials and intgernationally renowned endoscopists discusses the potential role of AI to evaluate and standardize endoscopic disease activity in IBD and the potential repevance of clinical decision support tools to guide clinicians to choose the best treatment options in IBD patients
January 7 · 25 min
Role of nutrition in the etiopathogenesis and treatment of IBD
Iris Dotan, Petah Tikva, Israel, former IOIBD president and international renowned expert in IBD and nutrition, discusses the role of nutrition in the pathogenesis of IBD and the potential of nutritional intervention to treat IBD and to modify the natural course of IBD
Dec 19, 2025 · 24 min
Highlights of new treatment options for IBD from recent phase II and III trials (Abtect, Gladiator, Astro, Graviti), definitions of mild IBD
Silvio Danese, Milan, internationally renowned IBD expert, former ECCO president and UEG Vice president discusses recent data from UEG 2025 on Etrasimod in mild UC (gladiator) and late breaking abstract data on obefazimod in ulcerative colitis
Dec 5, 2025 · 27 min
Meet the Editor Axel Dignass of our new series IBD Essentials
Axel Dignass, internationally renowned IBD expert and editor of the IBD Essentials vodcast, talks about his career and his plans for the podcast, the team, and upcoming topics

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