Ep 346: Sperm DNA Fragmentation & Male Fertility: What Actually Matters for IVF?
Does sperm DNA fragmentation affect IVF success, embryo quality, or miscarriage? And should you actually be tested for it? In this episode of Fertility Docs Uncensored, Dr. Susan Hudson and Dr. Carrie Bedient break down sperm DNA fragmentation—what it is, how it’s tested, what causes sperm DNA damage, and what you can actually do about it. From male fertility and sperm health to IVF outcomes and pregnancy loss, the docs tackle the questions patients are asking—and the controversies fertility specialists are still debating. They discuss how age, lifestyle, medical conditions, oxidative stress, and other factors can impact sperm DNA integrity, plus potential interventions including antioxidants, lifestyle changes, sperm preparation, and testicular sperm extraction (TESE). But does treating DNA fragmentation improve fertility outcomes? When is testing useful? And what do the latest fertility guidelines and research really say? No hype. No sugarcoating. Just an uncensored conversation about the science behind sperm DNA fragmentation and what it could mean for your fertility journey.
- Transcript