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Dr. Paika Podcast

Mohammed Paika

Welcome to the Dr. Paika Podcast — where medicine, fitness, and humanity come together.

Hosted by Dr. Mohammed K. Paika, M.D., double board-certified in obesity & internal medicine with over two decades of hospital experience, this show dives deep into the science of health, obesity, longevity, and mindset — but with compassion, not complexity.

From hospital medicine to the gym floor, from patient care to personal growth — every episode blends real clinical insight with practical, inspiring stories that help you live better and think deeper.

💡 Topics include:

Obesity & metabolic health

Longevity & fitness

Nutrition & preventive medicine

Doctor insights from 20+ years in hospitals across the US!

Mindset, mental health, and motivation

🎧 Subscribe for weekly conversations that are honest, empowering, and rooted in science — all from a doctor who believes medicine should heal the mind and body.

Play
  • 25 episodes
  • a few times a week
  • Avg 26 min
  • English
Counted on this page — what you have heard stays on this device, so it is not something the list can be paged by.
  • #96
    Yesterday · 23 min

    The Most Common Mistake Patients Make on Phentermine

    #Phentermine #WeightLoss #ObesityMedicine #GLP1 #weightlosstips The #1 mistake I see patients make on phentermine isn't a dosing error — it's that they stop eating. In this video, Dr. Mohammed Paika (board-certified in Internal Medicine and Obesity Medicine, 20 years as a hospitalist) breaks down exactly why appetite suppression gets confused with starvation, the real physiology of what happens to your metabolism and muscle when you under-eat on phentermine, a patient case from the hospital floor you won't forget, and the protein-first framework to actually keep the weight off long-term. You'll learn: – What phentermine actually does in your body (and why it's still the most-prescribed weight-loss medication in the U.S.) – The 3-stage physiology of "starvation mode" — and the real data behind it – A protein-first meal-timing framework you can start today – Why resistance training is non-negotiable for protecting your metabolism – Why phentermine isn't your only option — and how to know if it's the right one for you 🎓 Complete GLP-1 Weight Loss Masterclass — Lifetime Access Comprehensive education on GLP-1 medications, nutrition, exercise, muscle preservation, side effects & long-term success. Includes the companion eBook, quizzes, 12-week exercise program, certificate & future course updates at no additional cost. https://www.drmohammedpaika.com 📩 FREE GLP-1 Diet Cookbook + Weekly Newsletter Get weekly evidence-based insights on GLP-1s, metabolic health, nutrition, exercise & longevity. https://www.drmohammedpaika.com/newsletter 📚 The Weight Equation & The Physician’s Physique Physician-written, evidence-based guides to obesity, weight loss, nutrition, metabolism, exercise, body composition & healthier living. https://www.drmohammedpaika.com/books 👥 Metabolic Health Community https://www.skool.com/metabolic-health-community-5316 👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA Board-Certified in Internal Medicine and Obesity Medicine Certified Personal Trainer & Nutrition Coach Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine. Timestamps 0:00 Intro — The Mistake Almost Everyone Makes on Phentermine 1:05 What Phentermine Actually Does In Your Body 3:17 The Real Mistake: Not Eating 4:21 Why It Feels Like Winning At First 5:24 The 3 Stages of Starvation Mode 9:28 Free Resource: The GLP-1 Diet Cookbook 10:20 The Patient I'll Never Forget 12:26 What To Eat Instead: The Protein-First Framework 15:44 Protect Your Muscle & Metabolism 17:56 Phentermine Isn't Your Only Option 19:27 Playing The Long Game 21:43 The Bottom Line + Free Resources References U.S. FDA, Phentermine Hydrochloride prescribing information (Initial Approval 1959) Fothergill E, et al. Obesity. 2016;24(8):1612–1619 Lewis KH, et al. Obesity. 2019;27(4):591–602 Hunter GR, et al. Obesity. 2008;16(5):1045–1051 Mifflin MD, et al. Am J Clin Nutr. 1990;51(2):241–247 Wang Z, et al., organ metabolic rate research; Javed F, et al., body composition research NBC Sports / Olympics.com / EssentiallySports — reporting on Michael Phelps's diet Lewis KH, Gudzune KA, Ard JD. Current Obesity Reports. 2024;13(1):132–140 ⚕️ MEDICAL & EDUCATIONAL DISCLAIMER: This content is for general educational and informational purposes only and is not medical advice or a substitute for care from your healthcare provider. Viewing this content does not create a doctor-patient relationship. Always consult a qualified healthcare professional before starting, stopping, or changing any medication, diet, exercise, or weight-loss plan. Individual results and risks vary. You assume responsibility for decisions made based on this content.

  • #95
    Tuesday · 27 min

    How Does Zepbound (Tirzepatide) Really Compare to Wegovy (Semaglutide)?

    #Zepbound #Wegovy #Tirzepatide #Semaglutide #glp1 Zepbound and Wegovy are the two most talked-about weight loss medications right now — but the headlines comparing them skip the context that actually matters. In this video, I break down how tirzepatide (Zepbound) and semaglutide (Wegovy) actually work in your body, compare the real clinical trial data — including the new SURMOUNT-5 head-to-head trial — and walk through the side effects, cost, and questions you need to bring to your physician before choosing between them. I'm Dr. Mohammed Paika — board-certified in Internal Medicine and Obesity Medicine, and a practicing hospitalist for over 15 years. I built DrMohammedPaika.com to give people real, evidence-based guidance on GLP-1 medications, nutrition, and exercise, because a prescription without a plan for your muscle, your nutrition, and your training is only half a treatment. 🎓 Complete GLP-1 Weight Loss Masterclass — Lifetime Access Comprehensive education on GLP-1 medications, nutrition, exercise, muscle preservation, side effects & long-term success. Includes the companion eBook, quizzes, 12-week exercise program, certificate & future course updates at no additional cost. https://www.drmohammedpaika.com 📩 FREE GLP-1 Diet Cookbook + Weekly Newsletter Get weekly evidence-based insights on GLP-1s, metabolic health, nutrition, exercise & longevity. https://www.drmohammedpaika.com/newsletter 📚 The Weight Equation & The Physician’s Physique Physician-written, evidence-based guides to obesity, weight loss, nutrition, metabolism, exercise, body composition & healthier living. https://www.drmohammedpaika.com/books 👥 Metabolic Health Community https://www.skool.com/metabolic-health-community-5316 👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA Board-Certified in Internal Medicine and Obesity Medicine Certified Personal Trainer & Nutrition Coach Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine. Timestamps 00:00 Introduction 01:10 Who's Giving You This Information 03:22 Wegovy vs. Zepbound: The Timeline 04:52 How These Medications Actually Work 07:28 Dosing and What's New in 2026 10:01 Side Effects (And a Case From My Hospital) 13:11 Who Actually Qualifies 14:09 The Individual Trial Data: STEP 1 vs. SURMOUNT-1 15:22 SURMOUNT-5: The Head-to-Head Trial 17:28 Why the Average Doesn't Decide Your Case 18:17 The Part Everyone Skips: Your Muscle 20:16 What These Medications Cost in 2026 22:36 A Patient Case That Changed My Approach 24:14 Questions to Ask Your Physician 25:22 The Bottom Line 26:26 Where to Go From Here References Aronne LJ, et al. SURMOUNT-5, N Engl J Med (2025); Eli Lilly official results announcement, investor.lilly.com Baggio LL, Drucker DJ. Biology of Incretins: GLP-1 and GIP. Gastroenterology. 2007;132(6):2131-2157 U.S. FDA approval history: semaglutide (Ozempic) 2017; semaglutide (Wegovy) June 2021 Samms RJ, Coskun T, et al. Trends Endocrinol Metab. 2020;31(6):410-421 Coskun T, Sloop KW, et al. Mol Metab. 2018;18:3-14 Wegovy (semaglutide) U.S. Prescribing Information, Novo Nordisk Zepbound (tirzepatide) U.S. Prescribing Information, Eli Lilly FDA approval of oral semaglutide (Wegovy pill), OASIS-4 trial, 2025 Wilding JPH, et al. STEP 1. N Engl J Med. 2021;384:989-1002 Jastreboff AM, et al. SURMOUNT-1. N Engl J Med. 2022;387:205-216 He L, et al. JAMA Intern Med. 2022 (DOI 10.1001/jamainternmed.2022.0338) Neeland IJ, et al. Diabetes Obes Metab. 2024 (DOI 10.1111/dom.15728) Prado CM, Phillips SM, et al. Lancet Diabetes Endocrinol. 2024 (DOI 10.1016/S2213-8587(24)00272-9) NovoCare.com, Wegovy Cost, Coverage & Savings Resources, 2026 Eli Lilly investor announcement, LillyDirect Self Pay Journey Program pricing, 2026 ⚕️ MEDICAL & EDUCATIONAL DISCLAIMER: This content is for general educational and informational purposes only and is not medical advice or a substitute for care from your healthcare provider. Viewing this content does not create a doctor-patient relationship. Always consult a qualified healthcare professional before starting, stopping, or changing any medication, diet, exercise, or weight-loss plan. Individual results and risks vary. You assume responsibility for decisions made based on this content.

  • #94
    Saturday · 30 min

    5 Best Supplements for Longevity, Performance, and Overall Health

    #Supplements #Longevity #Creatine #Omega3 #glp1medications Feeling overwhelmed by the supplement aisle and not sure which five actually move the needle? As a board-certified internal medicine and obesity medicine physician (and a certified personal trainer), I'm cutting through the noise and giving you the only five supplements I actually recommend for longevity, performance, and overall health — with the real dose, the form that's actually absorbed, and the timing that matters, backed by the studies behind every claim. 🎓 Complete GLP-1 Weight Loss Masterclass — Lifetime Access Comprehensive education on GLP-1 medications, nutrition, exercise, muscle preservation, side effects & long-term success. Includes the companion eBook, quizzes, 12-week exercise program, certificate & future course updates at no additional cost. https://www.drmohammedpaika.com 📩 FREE GLP-1 Diet Cookbook + Weekly Newsletter Get weekly evidence-based insights on GLP-1s, metabolic health, nutrition, exercise & longevity. https://www.drmohammedpaika.com/newsletter 📚 The Weight Equation & The Physician’s Physique Physician-written, evidence-based guides to obesity, weight loss, nutrition, metabolism, exercise, body composition & healthier living. https://www.drmohammedpaika.com/books 👥 Metabolic Health Community https://www.skool.com/metabolic-health-community-5316 👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA Board-Certified in Internal Medicine and Obesity Medicine Certified Personal Trainer & Nutrition Coach Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine. Timestamps: 0:00 – Intro: the 5 supplements that actually work 1:10 – #5 Creatine: dose, form, and the brain benefit nobody mentions 6:46 – #4 Magnesium: the mineral running 300 systems you never think about 11:51 – #3 Vitamin D: how deficient is "deficient" 16:51 – Before we continue (free newsletter + GLP-1 Diet Cookbook) 17:42 – #2 Fiber: the supplement nobody thinks is sexy 22:51 – #1 Omega-3: heart, brain, and muscle recovery in one mechanism 26:57 – If you're on a GLP-1 medication: the real risk 29:31 – Where to go from here References: 1.Kreider RB, et al. ISSN position stand: creatine supplementation dosing. J Int Soc Sports Nutr. 2017;14:18. — Full text (PMC) 2. Creatine supplementation protocols on body composition: GRADE-assessed dose-response meta-analysis. J Int Soc Sports Nutr. 2024. — PubMed 3. Rosanoff A, Weaver CM, Rude RK. Suboptimal magnesium status in the U.S. Nutrition Reviews. 2012;70(3):153–164. — PubMed 4. NIH Office of Dietary Supplements. Magnesium: Fact Sheet for Health Professionals. — ods.od.nih.gov 5. Prevalence, trend, and predictor analyses of vitamin D deficiency in the U.S. population, 2001–2018. Frontiers in Nutrition. 2022. — Full text 6. Demay MB, et al. Vitamin D for the Prevention of Disease: Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2024;109(8):1907–1947. — PubMed 7. Holick MF, et al. Evaluation, Treatment, and Prevention of Vitamin D Deficiency: Endocrine Society Guideline. J Clin Endocrinol Metab. 2011;96(7):1911–1930. — Journal page 8. Dietary fiber intake and all-cause/cause-specific mortality: dose-response meta-analysis. Frontiers in Nutrition. 2023;10:1153165. — Full text 9. Kapoor MP, et al. Partially hydrolysed guar gum and postprandial glucose/lipid response. Journal of Functional Foods. 2016. — Journal page 10. Bhatt DL, et al. Cardiovascular Risk Reduction with Icosapent Ethyl (REDUCE-IT). NEJM. 2019;380:11–22. — NEJM 11. Harris WS, von Schacky C. The Omega-3 Index. Preventive Medicine. 2004;39(1):212–220. — Journal page 12. STEP 1 DXA body-composition substudy (semaglutide). — PMC 13. Look M, et al. SURMOUNT-1 body composition analysis (tirzepatide). Diabetes, Obesity and Metabolism. 2025. — PubMed ⚕️ MEDICAL & EDUCATIONAL DISCLAIMER: This content is for general educational and informational purposes only and is not medical advice or a substitute for care from your healthcare provider. Viewing this content does not create a doctor-patient relationship. Always consult a qualified healthcare professional before starting, stopping, or changing any medication, diet, exercise, or weight-loss plan. Individual results and risks vary. You assume responsibility for decisions made based on this content.

  • #93
    August 27 · 30 min

    If I Started Retatrutide Today, Here’s EXACTLY What I’d Do!

    #Retatrutide #GLP1 #WeightLoss #ObesityMedicine #metabolichealth Retatrutide is producing weight loss results we used to only see after bariatric surgery — but the medication is only half the story. In this video, Dr. Mohammed Paika (board-certified in internal medicine and obesity medicine) breaks down the five decisions he'd make before ever taking a first dose: how to find the right dose instead of chasing the highest one, why your heart rate and mood deserve the same attention as the scale, how to protect your muscle while the weight comes off, how to build a supplement plan instead of guessing, and why the medication should never be allowed to do all the work on its own. Important: as of this video, retatrutide is still investigational and not yet FDA approved. Eli Lilly has completed three positive Phase 3 trials and plans to file for approval in Q1 2027. Right now it's accessible only through clinical trials or a narrow compassionate-use program — this video is the plan to have ready before that changes. 🎓 Complete GLP-1 Weight Loss Masterclass — Lifetime Access Comprehensive education on GLP-1 medications, nutrition, exercise, muscle preservation, side effects & long-term success. Includes the companion eBook, quizzes, 12-week exercise program, certificate & future course updates at no additional cost. https://www.drmohammedpaika.com 📩 FREE GLP-1 Diet Cookbook + Weekly Newsletter Get weekly evidence-based insights on GLP-1s, metabolic health, nutrition, exercise & longevity. https://www.drmohammedpaika.com/newsletter 📚 The Weight Equation & The Physician’s Physique Physician-written, evidence-based guides to obesity, weight loss, nutrition, metabolism, exercise, body composition & healthier living. https://www.drmohammedpaika.com/books 👥 Metabolic Health Community https://www.skool.com/metabolic-health-community-5316 Timestamps 0:00 – Intro 2:38 – Where Things Stand: Is Retatrutide FDA Approved? 4:35 – Rule 1: Dosing Is Not a Competition 10:37 – Rule 2: The Scale Doesn't See Everything (Heart + Mood) 16:50 – Rule 3: Muscle Is Not Optional 21:30 – Rule 4: Supplements Need a Strategy, Not a Guess 24:26 – Rule 5: Don't Let the Medication Do All the Work 28:15 – The Five Decisions That Actually Matter 29:18 – What To Do Next References TRIUMPH-1 phase 3 trial results (weight loss %, BMI outcomes, discontinuation rates) — https://www.ajmc.com/view/retatrutide-achieves-up-to-30-3-average-weight-loss-in-phase-3-triumph-1-trial TRIUMPH-1 trial summary and safety profile — https://www.hcplive.com/view/retatrutide-weight-loss-endpoints-phase-3-obesity-trial Retatrutide phase 2 data — mechanism and heart rate increase (~6.7 bpm), Doggrell, Expert Opinion on Investigational Drugs, 2023 — https://pubmed.ncbi.nlm.nih.gov/37947489/ FDA Drug Safety Communication — removal of suicidal ideation/behavior warning from GLP-1 receptor agonist labels (January 2026) — https://www.fda.gov/drugs/drug-safety-communications/fda-requests-removal-suicidal-behavior-and-ideation-warning-glucagon-peptide-1-receptor-agonist-glp Lilly TRIUMPH-2 and TRIUMPH-3 phase 3 results and planned Q1 2027 BLA submission — https://investor.lilly.com/news-releases/news-release-details/lillys-triple-agonist-retatrutide-successful-two-additional Retatrutide access status, August 2026 — https://www.ajmc.com/view/lilly-expands-retatrutide-access-amid-doctor-pushback Lean body mass loss data (SURMOUNT-1, STEP-1) and 2025 joint medical-society advisory — https://www.healio.com/news/endocrinology/20251114/muscle-matters-the-challenge-of-preserving-lean-mass-during-obesity-treatment Fothergill et al., "Persistent metabolic adaptation 6 years after The Biggest Loser competition," Obesity, 2016 — https://onlinelibrary.wiley.com/doi/full/10.1002/oby.21538 American Medical Association's 2013 classification of obesity as a chronic disease — https://abcnews.go.com/Health/american-medical-association-classifies-obesity-disease/story?id=19439304 and https://obesitymedicine.org/blog/ama-adopts-policy-recognize-obesity-disease/ "GLP-1 personality" — patient-reported emotional blunting and researcher commentary — https://health.yahoo.com/your-body/weight-management/weight-loss/article/what-is-ozempic-personality-125300474.html Protein targets and resistance-training rationale — Dr. Paika's GLP-1 Masterclass, Chapters 7 & 13 (internal course material) ⚕️ MEDICAL & EDUCATIONAL DISCLAIMER This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional. Viewing this content does not create a doctor-patient relationship between you and Dr. Paika. Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

  • #92
    August 25 · 17 min

    Tips That Can Help Manage Your Ozempic Side Effects

    #Ozempic #Wegovy #GLP1 #WeightLoss #obesitymedicine Nausea, constipation, bloating, gas — if you're on semaglutide (Ozempic or Wegovy), gastrointestinal side effects are the most common thing you'll run into. In this video, I break down exactly why they happen and the specific, evidence-based strategies that actually reduce them: portion sizes, meal timing, which foods make it worse, hydration, injection timing, dose titration, and the red flags that mean it's time to call your doctor — not internet folklore, actual clinical data and two decades of hospital medicine. 🎓 Complete GLP-1 Weight Loss Masterclass — Lifetime Access Comprehensive education on GLP-1 medications, nutrition, exercise, muscle preservation, side effects & long-term success. Includes the companion eBook, quizzes, 12-week exercise program, certificate & future course updates at no additional cost. https://www.drmohammedpaika.com 📩 FREE GLP-1 Diet Cookbook + Weekly Newsletter Get weekly evidence-based insights on GLP-1s, metabolic health, nutrition, exercise & longevity. https://www.drmohammedpaika.com/newsletter 📚 The Weight Equation & The Physician’s Physique Physician-written, evidence-based guides to obesity, weight loss, nutrition, metabolism, exercise, body composition & healthier living. https://www.drmohammedpaika.com/books 👥 Metabolic Health Community Live Q&As, evidence-based education, accountability, workouts, nutrition guidance & community support. https://www.skool.com/metabolic-health-community-5316 TIMESTAMPS 0:00 – Intro & Disclaimer 1:35 – What Semaglutide Actually Is (and Why Side Effects Happen) 3:22 – Tip 1: Cut Your Portions 5:14 – Tip 2: Smaller, More Frequent Meals 6:27 – Tip 3: Foods That Work Against You 8:04 – Tip 4: Hydration & Constipation 9:04 – Tip 5: Time Your Injection Around Your Life 9:45 – Tip 6: Injection Site — Myth vs. Evidence 11:38 – Tip 7: Titration Schedule 12:34 – The Symptom Timeline: When It Gets Better 13:35 – When to Call Your Doctor 14:39 – The Bigger Picture 16:01 – Resources & Next Steps Wilding JPH, Batterham RL, Calanna S, et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. New England Journal of Medicine. 2021;384:989-1002. — https://www.nejm.org/doi/full/10.1056/NEJMoa2032183 Wharton S, Davies M, Dicker D, Lingvay I, Mosenzon O, Rubino DM, Pedersen SD. Managing the gastrointestinal side effects of GLP-1 receptor agonists in obesity: recommendations for clinical practice. Postgraduate Medicine. 2022;134(1):14-19. — https://www.tandfonline.com/doi/full/10.1080/00325481.2021.2002616 Mozaffarian D, et al. Nutritional priorities to support GLP-1 therapy for obesity: a joint Advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Society. Obesity. 2025. — https://ajcn.nutrition.org/article/S0002-9165(25)00240-0/fulltext Saha B, Kamalumpundi V, Codipilly DC. GLP1 and GIP Receptor Agonists: Effects on the Gastrointestinal Tract and Management Strategies for Primary Care Physicians. Mayo Clinic Proceedings. 2025. — https://www.mayoclinicproceedings.org/article/S0025-6196(25)00551-8/fulltext Novo Nordisk. Ozempic (semaglutide) injection Prescribing Information. — https://www.novo-pi.com/ozempic.pdf Novo Nordisk. Wegovy (semaglutide) injection Prescribing Information. — https://www.novo-pi.com/wegovy.pdf FDA Clinical Pharmacology Review, NDA 215866 (tirzepatide) — injection site bioequivalence data, cited in the corrected Tip 6. — https://www.accessdata.fda.gov/drugsatfda_docs/nda/2022/215866Orig1s000ClinPharmR.pdf ⚕️ MEDICAL & EDUCATIONAL DISCLAIMER This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional. Viewing this content does not create a doctor-patient relationship between you and Dr. Paika. Health, nutrition, exercise, and medication topics discussed on this channel may not be appropriate for all individuals. Always consult your own healthcare provider before starting or changing any medication, diet, exercise program, or weight-loss plan, including GLP-1 therapies such as Wegovy, Ozempic, Zepbound, Mounjaro, or similar medications. Exercise and lifestyle changes carry inherent risks. By choosing to follow any information from this channel, you accept full responsibility for your health decisions and outcomes. Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

  • #91
    August 22 · 30 min

    Best Foods to Eat on GLP-1: Ozempic, Mounjaro, Zepbound & Wegovy Diet

    #GLP1 #Ozempic #WeightLossJourney #ObesityMedicine #healthyeating Eating less on Ozempic, Wegovy, Mounjaro, or Zepbound doesn't automatically mean your diet is helping you lose fat. In this video, I break down the best foods to eat on a GLP-1 — protein, carbs, healthy fats, and fiber — so you preserve muscle, manage side effects, and get better results from your medication. I'm Dr. Mohammed Paika, a board-certified internal medicine and obesity medicine physician. Everything in this video comes from the same nutrition science I use with real patients, including two cases straight from my hospital work. 🎓 Complete GLP-1 Weight Loss Masterclass — Lifetime Access Comprehensive education on GLP-1 medications, nutrition, exercise, muscle preservation, side effects & long-term success. Includes the companion eBook, quizzes, 12-week exercise program, certificate & future course updates at no additional cost. https://www.drmohammedpaika.com 📩 FREE GLP-1 Diet Cookbook + Weekly Newsletter Get weekly evidence-based insights on GLP-1s, metabolic health, nutrition, exercise & longevity. https://www.drmohammedpaika.com/newsletter 📚 The Weight Equation & The Physician’s Physique Physician-written, evidence-based guides to obesity, weight loss, nutrition, metabolism, exercise, body composition & healthier living. https://www.drmohammedpaika.com/books 👥 Metabolic Health Community Live Q&As, evidence-based education, accountability, workouts, nutrition guidance & community support. https://www.skool.com/metabolic-health-community-5316 TImestamps 0:00 Introduction — Why Food Choices Matter More on a GLP-1 2:07 How GLP-1 Medications Actually Work 5:17 Protein: Why It's Non-Negotiable 12:44 Carbohydrates: The Fuel You're Still Allowed to Eat 14:40 Healthy Fats: Small Amounts, Real Benefit 15:53 Fiber: The Nutrient That Makes Everything Else Work 20:40 Water: The One Everyone Forgets 23:26 How to Build Your GLP-1 Plate 24:57 Warning Signs: When to Call Your Doctor 26:46 What Realistic Progress Looks Like 27:28 Bringing It All Together 28:41 Resources & Next Steps References 1. Mozaffarian D, et al. Nutritional priorities to support GLP-1 therapy for obesity. Am J Clin Nutr. 2025. https://ajcn.nutrition.org/article/S0002-9165(25)00240-0/fulltext 2. Villareal DT, et al. Weight Loss, Exercise, or Both and Physical Function in Obese Older Adults. NEJM. 2011. https://pubmed.ncbi.nlm.nih.gov/21449785/ 3. Leidy HJ, et al. Higher protein intake preserves lean mass and satiety with weight loss. Obesity. 2007. https://pubmed.ncbi.nlm.nih.gov/17299116/ 4. Cruz-Jentoft AJ, et al. Sarcopenia: revised European consensus on definition and diagnosis (EWGSOP2). Age Ageing. 2019. https://pmc.ncbi.nlm.nih.gov/articles/PMC6593317/ 5. Sacks FM, et al. Comparison of weight-loss diets with different compositions of fat, protein, and carbohydrates. NEJM. 2009. https://pubmed.ncbi.nlm.nih.gov/19246357/ 6. Johnston BC, et al. Comparison of weight loss among named diet programs in overweight and obese adults. JAMA. 2014. https://pubmed.ncbi.nlm.nih.gov/25182101/ 7. Rolls BJ. Dietary energy density: applying behavioural science to weight management. Nutr Bull. 2017. https://onlinelibrary.wiley.com/doi/abs/10.1111/nbu.12280 8. Estruch R, et al. Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts (PREDIMED). NEJM. 2018. https://pubmed.ncbi.nlm.nih.gov/29897866/ 9. USDA & HHS. Dietary Guidelines for Americans, 2020-2025. https://www.dietaryguidelines.gov/sites/default/files/2020-12/Dietary_Guidelines_for_Americans_2020-2025.pdf 10. American College of Sports Medicine. Position Stand — Resistance Training Prescription for Muscle Function, Hypertrophy, and Physical Performance in Healthy Adults. Med Sci Sports Exerc. 2026. https://pubmed.ncbi.nlm.nih.gov/41843416/ 11. American Society of Anesthesiologists. Consensus-Based Guidance on Preoperative Management of Patients on GLP-1 Receptor Agonists. 2023. https://www.asahq.org/about-asa/newsroom/news-releases/2023/06/american-society-of-anesthesiologists-consensus-based-guidance-on-preoperative ⚕️ MEDICAL & EDUCATIONAL DISCLAIMER This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional. Viewing this content does not create a doctor-patient relationship between you and Dr. Paika. Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

  • #90
    August 20 · 29 min

    Ozempic and Mounjaro Warning! What They’re Not Telling You!

    #Ozempic #Mounjaro #GLP1 #WeightLoss #ObesityMedicine Ozempic and Mounjaro can be powerful weight-loss tools — but they can also affect your body in ways many people aren't told before starting. In this video, I break down the real risks, the paradox in the trial data, and what to actually watch for. In this video I walk through why people with type 2 diabetes tend to lose less weight on these medications than people without it, why a meaningful share of the weight lost on GLP-1s can be muscle rather than fat, what the data actually shows about gastroparesis and other GI complications, what happens metabolically when you stop the medication, how bariatric surgery compares, and exactly what to do to protect your muscle and your health if you're on one of these drugs. Timestamps: 00:00 The risks nobody tells you about 01:12 Who I am, and why this topic keeps me up at night 03:04 The paradox no one is talking about 04:56 Why your brain needs data from your gut 07:01 The detail your prescriber probably never mentioned 09:26 The lesson every doctor should remember 11:21 A quick word before we go further 12:14 The muscle you didn't know you were losing 17:03 When the stomach stops working 20:16 What happens when you stop 21:03 Why bariatric surgery tells a different story 24:11 What to actually do about it 26:30 The bottom line 27:36 Where to go from here 🎓 Complete GLP-1 Weight Loss Masterclass — Lifetime Access Comprehensive education on GLP-1 medications, nutrition, exercise, muscle preservation, side effects & long-term success. Includes the companion eBook, quizzes, 12-week exercise program, certificate & future course updates at no additional cost. https://www.drmohammedpaika.com 📩 FREE GLP-1 Diet Cookbook + Weekly Newsletter Get weekly evidence-based insights on GLP-1s, metabolic health, nutrition, exercise & longevity. https://www.drmohammedpaika.com/newsletter 📚 The Weight Equation & The Physician’s Physique Physician-written, evidence-based guides to obesity, weight loss, nutrition, metabolism, exercise, body composition & healthier living. https://www.drmohammedpaika.com/books 👥 Metabolic Health Community Live Q&As, evidence-based education, accountability, workouts, nutrition guidance & community support. https://www.skool.com/metabolic-health-community-5316 👍 Like 💬 Comment 📌 Share 🔔 Subscribe for more honest conversations about obesity, metabolism, hormones, and real-world health solutions Bohórquez DV, et al. Gut sensor cells & the vagus nerve. Science, 2018. https://doi.org/10.1126/science.aat5236 Holst JJ. The physiology of glucagon-like peptide 1. Physiological Reviews, 2007. https://doi.org/10.1152/physrev.00034.2006 Semaglutide weight loss with vs. without type 2 diabetes — meta-analysis. Pharmaceuticals (Basel), 2025. https://pmc.ncbi.nlm.nih.gov/articles/PMC12300051/ ACCORD Study Group. Effects of intensive glucose lowering in type 2 diabetes. NEJM, 2008. https://www.nejm.org/doi/full/10.1056/NEJMoa0802743 Gamble JM, et al. Insulin dosage and mortality — confounding example. Lancet Diabetes & Endocrinology, 2017. https://doi.org/10.1016/S2213-8587(16)30316-3 Look M, et al. Body composition changes with tirzepatide (SURMOUNT-1). Diabetes, Obesity and Metabolism, 2025. https://doi.org/10.1111/dom.16275 Wilding JPH, et al. Body composition analysis (STEP 1 study). Conference abstract. https://www.newswise.com/pdf_docs/16159288255831_Wilding%20Abstract.pdf Wilding JPH, et al. Weight regain after stopping semaglutide (STEP 1 extension). Diabetes, Obesity and Metabolism, 2022. https://pmc.ncbi.nlm.nih.gov/articles/PMC9542252/ Sodhi M, et al. GI adverse events with GLP-1 receptor agonists. JAMA, 2023. https://pubmed.ncbi.nlm.nih.gov/37796527/ FDA. Wegovy (semaglutide) prescribing information. https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/215256s007lbl.pdf Obesity Surgery, 2023. https://pubmed.ncbi.nlm.nih.gov/36336720/ Chris Christie's 2013 lap-band surgery. U.S. News & World Report. https://www.usnews.com/news/articles/2013/05/07/chris-christie-admits-to-lap-band-surgery ⚕️ MEDICAL & EDUCATIONAL DISCLAIMER This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional. Viewing this content does not create a doctor-patient relationship between you and Dr. Paika. Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

  • #89
    August 18 · 22 min

    Stop Eating These Foods on Ozempic & Mounjaro Before It’s Too Late

    #Ozempic #Mounjaro #GLP1 #WeightLoss #ObesityMedicine Some foods can make Ozempic or Mounjaro side effects much worse — even if you're taking the medication exactly as prescribed. In this video, Dr. Mohammed Paika (board-certified in Internal Medicine and Obesity Medicine) breaks down the 5 food categories most likely to cause nausea, reflux, and bloating on a GLP-1 medication — and exactly what to eat instead to support fat loss without fighting your own treatment. 🎓 Complete GLP-1 Weight Loss Masterclass — Lifetime Access Comprehensive education on GLP-1 medications, nutrition, exercise, muscle preservation, side effects & long-term success. Includes the companion eBook, quizzes, 12-week exercise program, certificate & future course updates at no additional cost. https://www.drmohammedpaika.com 📩 FREE GLP-1 Diet Cookbook + Weekly Newsletter Get weekly evidence-based insights on GLP-1s, metabolic health, nutrition, exercise & longevity. https://www.drmohammedpaika.com/newsletter 📚 The Weight Equation & The Physician’s Physique Physician-written, evidence-based guides to obesity, weight loss, nutrition, metabolism, exercise, body composition & healthier living. https://www.drmohammedpaika.com/books 👥 Metabolic Health Community Live Q&As, evidence-based education, accountability, workouts, nutrition guidance & community support. https://www.skool.com/metabolic-health-community-5316 Timestamps: 0:00 Hook 0:51 Who I Am & Why This Matters 3:11 Fried & Greasy Foods 6:30 Alcohol 9:37 A Quick Word (GLP-1 Masterclass) 10:54 Easy-to-Overeat Carbs 13:01 Candy & Processed Sweets 15:23 Sugary Drinks 18:54 The Mindset That Actually Works 20:37 End-Screen / Resources 👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA Board-Certified in Internal Medicine and Obesity Medicine Certified Personal Trainer & Nutrition Coach Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine. References: Jelsing et al., 2012, Diabetes Obes Metab — https://pubmed.ncbi.nlm.nih.gov/22226053/ Little et al., 2005, Obes Rev — https://doi.org/10.1111/j.1467-789X.2005.00212.x Sodhi et al., 2023, JAMA — https://pubmed.ncbi.nlm.nih.gov/37796527/ Suter et al., 1992, N Engl J Med — https://www.nejm.org/doi/full/10.1056/NEJM199204093261503 American Diabetes Association, 2024, Standards of Care — https://diabetesjournals.org/care/issue/47/Supplement_1 Graybiel, 2008, Annu Rev Neurosci — https://pubmed.ncbi.nlm.nih.gov/18558860/ Hall et al., 2019, Cell Metab — https://pubmed.ncbi.nlm.nih.gov/31105044/ Nauck & Meier, 2018, Diabetes Obes Metab — https://pubmed.ncbi.nlm.nih.gov/29364588/ Wilding et al., 2021, N Engl J Med (STEP 1 trial) — https://pubmed.ncbi.nlm.nih.gov/33567185/ McDonald's — Large Sweet Tea nutrition — https://www.mcdonalds.com/us/en-us/product/southern-style-sweet-tea-large.html Starbucks — Caramel Frappuccino nutrition — https://www.starbucks.com/menu/product-info/?product=caramel-frappuccino-blended-beverage Volkow, Wang & Baler, 2011, Trends Cogn Sci — https://pubmed.ncbi.nlm.nih.gov/21109477/ DiMeglio & Mattes, 2000, Int J Obes — https://pubmed.ncbi.nlm.nih.gov/10878689/ ⚕️ MEDICAL & EDUCATIONAL DISCLAIMER This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional. Viewing this content does not create a doctor-patient relationship between you and Dr. Paika. Health, nutrition, exercise, and medication topics discussed on this channel may not be appropriate for all individuals. Always consult your own healthcare provider before starting or changing any medication, diet, exercise program, or weight-loss plan, including GLP-1 therapies such as Wegovy, Ozempic, Zepbound, Mounjaro, or similar medications. Exercise and lifestyle changes carry inherent risks. By choosing to follow any information from this channel, you accept full responsibility for your health decisions and outcomes. Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

  • #88
    August 16 · 24 min

    This Training Method Is Getting Men Over 50 Jacked

    #muscleafter50 #GLP1 #MenOver50Fitness #EvidenceBasedTraining #obesitymedicine Building muscle after 50 doesn't work the way it used to — and "just lift heavier" is exactly why most men stay stuck, sore, and stalled. In this video, I break down an evidence-based training framework grounded in NASM's OPT model and backed by ACSM/NSCA resistance-training guidelines for older adults — built to build real muscle while protecting your joints, tendons, and long-term mobility. I also cover why muscle matters even more if you're on a GLP-1 medication, and what the research actually shows about lean mass loss during weight loss. 🎓 Complete GLP-1 Weight Loss Masterclass — Lifetime Access Comprehensive education on GLP-1 medications, nutrition, exercise, muscle preservation, side effects & long-term success. Includes the companion eBook, quizzes, 12-week exercise program, certificate & future course updates at no additional cost. https://www.drmohammedpaika.com 📩 FREE GLP-1 Diet Cookbook + Weekly Newsletter Get weekly evidence-based insights on GLP-1s, metabolic health, nutrition, exercise & longevity. https://www.drmohammedpaika.com/newsletter 📚 The Weight Equation & The Physician’s Physique Physician-written, evidence-based guides to obesity, weight loss, nutrition, metabolism, exercise, body composition & healthier living. https://www.drmohammedpaika.com/books 👥 Metabolic Health Community Live Q&As, evidence-based education, accountability, workouts, nutrition guidance & community support. https://www.skool.com/metabolic-health-community-5316 Timestamps 00:00 Intro / The Hook 02:17 Why Your Old Approach Stops Working After 50 05:30 The Science of How Muscle Actually Grows 07:07 The Framework: NASM's OPT Model (Phase 1 & 2) 11:19 What the Exercise-Medicine Guidelines Say (NSCA/ACSM) 13:02 Why This Framework Works Better for Men Over 50 16:02 How to Structure a Chest, Back & Leg Workout 18:51 Advanced Technique: Stacking for More 19:55 Why Muscle Is the Real Longevity Drug 22:14 Your Next Step References Schoenfeld (2010) – Mechanisms of Muscle Hypertrophy: https://journals.lww.com/nsca-jscr/fulltext/2010/10000/the_mechanisms_of_muscle_hypertrophy_and_their.40.aspx Harman et al. – Testosterone Decline, Baltimore Longitudinal Study of Aging: https://pubmed.ncbi.nlm.nih.gov/11158037/ Kubo et al. (2001) – Isometric Training & Tendon Elasticity: https://journals.physiology.org/doi/full/10.1152/jappl.2001.91.1.26 Bohm et al. (2015) – Tendon Adaptation to Mechanical Loading: https://pubmed.ncbi.nlm.nih.gov/27747846/ NASM – The OPT Model: https://www.nasm.org/certified-personal-trainer/the-opt-model Fragala et al. (2019) – NSCA Resistance Training for Older Adults: https://journals.lww.com/nsca-jscr/fulltext/2019/08000/resistance_training_for_older_adults__position.1.aspx ACSM (2009) – Progression Models in Resistance Training: https://pubmed.ncbi.nlm.nih.gov/19204579/ Wilding et al. (2021) – STEP 1 Trial (NEJM): https://www.nejm.org/doi/full/10.1056/NEJMoa2032183 Jastreboff et al. – SURMOUNT-1 Body Composition Data: https://pubmed.ncbi.nlm.nih.gov/39996356/ ⚠️ MEDICAL & EXERCISE DISCLAIMER This video is provided for general educational and informational purposes only. It is not intended to provide individualized medical advice, diagnosis, treatment, or exercise prescription and should not be used as a substitute for evaluation or care from your own qualified healthcare professional. Any medications, treatments, nutrition strategies, supplements, exercises, or other health-related examples discussed in this video are general in nature and may not be appropriate for everyone. Do not start, stop, or change any medication or treatment based solely on information presented in this video. Decisions regarding your health and medical care should be made with your own healthcare professional based on your individual circumstances. Exercise and physical activity involve inherent risks. Before attempting any exercises shown or discussed, consider your health, fitness level, medical conditions, medications, injuries, physical limitations, balance, and mobility. Exercise within your individual abilities and limitations and use proper form. Stop exercising if you experience pain, significant discomfort, dizziness, faintness, chest pain, unusual shortness of breath, or other concerning symptoms. If you have an existing medical condition, injury, physical limitation, have been advised to restrict physical activity, or are unsure whether an exercise is appropriate for you, consult your healthcare professional before proceeding. If you cannot perform an exercise safely or with proper form, do not force the movement. Modify the exercise, choose an appropriate alternative, or avoid it as appropriate for your individual circumstances. Viewing this video or interacting with its content does not establish a physician-patient relationship. 🎬 STOCK FOOTAGE DISCLOSURE -Stock media used under license from Storyblocks.

  • #87
    August 13 · 25 min

    Ozempic and Your Brain: What They Aren’t Telling You

    #Ozempic #GLP1 #BrainHealth #WeightLoss #obesitymedicine A physician breaks down what Ozempic really does to your brain — benefits, risks, and what the science actually shows. 🎓 Complete GLP-1 Weight Loss Masterclass — Lifetime Access Comprehensive education on GLP-1 medications, nutrition, exercise, muscle preservation, side effects & long-term success. Includes the companion eBook, quizzes, 12-week exercise program, certificate & future course updates at no additional cost. https://www.drmohammedpaika.com 📩 FREE GLP-1 Diet Cookbook + Weekly Newsletter Get weekly evidence-based insights on GLP-1s, metabolic health, nutrition, exercise & longevity. https://www.drmohammedpaika.com/newsletter 📚 The Weight Equation & The Physician’s Physique Physician-written, evidence-based guides to obesity, weight loss, nutrition, metabolism, exercise, body composition & healthier living. https://www.drmohammedpaika.com/books 👥 Metabolic Health Community Live Q&As, evidence-based education, accountability, workouts, nutrition guidance & community support. https://www.skool.com/metabolic-health-community-5316 TIMESTAMPS 00:00 Intro — What Ozempic Really Does to Your Brain 00:54 Who This Is For (and Who I Am) 01:49 How GLP-1 Drugs Talk to Your Brain 03:34 The Whole-Body Domino Effect 04:43 The Immune System Gets a Reset 05:57 Neuroprotection: BDNF, Amyloid & Tau 07:31 Does This Prevent Dementia? The Evidence, Ranked 12:05 Addiction Circuitry: Alcohol, Nicotine & Dopamine 15:40 Psychotic Disorders: Why Not Much Is Expected 16:28 Mood & Anxiety (+ the Jan 2026 FDA Update) 19:02 Eating Disorders: Binge Eating & Bulimia 21:13 Cardiovascular & Stroke Protection 23:22 The Full Picture 24:38 What to Do Next References 1. Wilding JPH, et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1). NEJM, 2021. https://pubmed.ncbi.nlm.nih.gov/33567185/ 2. Lincoff AM, et al. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (SELECT trial). NEJM, 2023. https://pubmed.ncbi.nlm.nih.gov/37952131/ 3. Rhea EM, Banks WA. Obesity-induced blood-brain barrier dysfunction: phenotypes and mechanisms. J Neuroinflammation, 2024. https://pmc.ncbi.nlm.nih.gov/articles/PMC11056074/ 4. GLP-1 programs the neurovascular landscape. Cell Metabolism, 2024. https://www.cell.com/cell-metabolism/fulltext/S1550-4131(24)00367-X 5. Efficacy and safety of oral semaglutide in early-stage symptomatic Alzheimer's disease (EVOKE/EVOKE+ trials). The Lancet, 2026. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)00459-9/fulltext 6. Wang W, et al. Associations of semaglutide with first-time diagnosis of Alzheimer's disease in patients with type 2 diabetes: target trial emulation using nationwide real-world data in the US. Alzheimer's & Dementia, 2024. https://alz-journals.onlinelibrary.wiley.com/doi/full/10.1002/alz.14313 7. Wang W, Volkow ND, et al. Associations of semaglutide with incidence and recurrence of alcohol use disorder in a real-world population. Nature Communications, 2024. https://www.nature.com/articles/s41467-024-48780-6 8. Hendershot CS, et al. Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial. JAMA Psychiatry, 2025. https://pubmed.ncbi.nlm.nih.gov/39937469/ 9. Once-weekly semaglutide vs. placebo in alcohol use disorder and comorbid obesity: RCT. The Lancet, 2026. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)00305-3/fulltext 10. Volkow ND, Xu R. GLP-1R agonist medications for addiction treatment. Addiction, 2025. https://onlinelibrary.wiley.com/doi/10.1111/add.16626 11. FDA Drug Safety Communication: FDA Requests Removal of Suicidal Behavior and Ideation Warning from GLP-1 RA Medications. Jan 13, 2026. https://www.fda.gov/drugs/drug-safety-communications/fda-requests-removal-suicidal-behavior-and-ideation-warning-glucagon-peptide-1-receptor-agonist-glp 12. EMA review finds no link between GLP-1 receptor agonists and suicidal thoughts. April 2024. https://pharmaceutical-journal.com/article/news/ema-finds-no-link-between-glp-1-receptor-agonists-and-suicidal-thoughts 13. Richards J, et al. Successful treatment of binge eating disorder with the GLP-1 agonist semaglutide: a retrospective cohort study. Obesity Pillars, 2023. https://www.sciencedirect.com/science/article/pii/S2667368123000268 14. Fothergill E, et al. Persistent metabolic adaptation 6 years after "The Biggest Loser" competition. Obesity, 2016. https://pubmed.ncbi.nlm.nih.gov/27136388/ ⚕️ MEDICAL & EDUCATIONAL DISCLAIMER⚕️ MEDICAL & EDUCATIONAL DISCLAIMER This content is for general educational and informational purposes only and is not medical advice or a substitute for care from your healthcare provider. Viewing this content does not create a doctor-patient relationship with Dr. Mohammed K. Paika. Always consult your healthcare provider before making changes to medications, diet, exercise, or weight-loss treatment, including GLP-1 therapies. Individual risks and results vary

  • #86
    August 11 · 29 min

    10 Things You Should NEVER Mix with Ozempic or Mounjaro

    #Ozempic #Mounjaro #GLP1 #WeightLoss #obesitymedicine Ozempic and Mounjaro are two of the most powerful tools we've ever had for weight loss and metabolic health — but what you combine them with matters. In this video, Dr. Mohammed Paika, MD (board-certified in Internal Medicine and Obesity Medicine, hospitalist for nearly 20 years) breaks down 10 medications, substances, and habits that can quietly work against your GLP-1 treatment: SGLT2 inhibitors, metformin, cannabis/THC, artificial sweeteners and sugar alcohols, compounded/gray-market GLP-1 products, skipping resistance training, SSRIs, caffeine, diuretics, and stacking multiple GLP-1 medications. You'll learn the actual physiology behind each risk, real warning signs to watch for, and what to do instead — so your treatment stays safer, easier to stick with, and more effective. 🎓 Complete GLP-1 Weight Loss Masterclass — Lifetime Access Comprehensive education on GLP-1 medications, nutrition, exercise, muscle preservation, side effects & long-term success. Includes the companion eBook, quizzes, 12-week exercise program, certificate & future course updates at no additional cost. https://www.drmohammedpaika.com 📩 FREE GLP-1 Diet Cookbook + Weekly Newsletter Get weekly evidence-based insights on GLP-1s, metabolic health, nutrition, exercise & longevity. https://www.drmohammedpaika.com/newsletter 📚 The Weight Equation & The Physician’s Physique Physician-written, evidence-based guides to obesity, weight loss, nutrition, metabolism, exercise, body composition & healthier living. https://www.drmohammedpaika.com/books 👥 Metabolic Health Community Live Q&As, evidence-based education, accountability, workouts, nutrition guidance & community support. https://www.skool.com/metabolic-health-community-5316 Timestamps 0:00 Intro — Why This List Matters 0:42 Meet Dr. Paika + The Ground Rule 1:50 #1 SGLT2 Inhibitors (Euglycemic DKA Risk) 4:34 #2 Metformin 6:59 #3 Cannabis & THC Products 9:12 #4 Artificial Sweeteners & Sugar Alcohols 11:37 Quick Break + Free Resources 13:04 #5 Compounded/Gray-Market GLP-1s 15:25 #6 Skipping Resistance Training 17:57 #7 SSRIs & Serotonergic Medications 20:03 #8 Caffeine 22:12 #9 Diuretics 24:37 #10 Stacking Multiple GLP-1 Medications 26:58 The Bottom Line 27:32 What to Watch Next Sources & References: Ozempic (semaglutide) FDA label — https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/209637s035,209637s037lbl.pdf Mounjaro (tirzepatide) FDA label — https://www.accessdata.fda.gov/drugsatfda_docs/label/2026/215866s041lbl.pdf SGLT2 inhibitors + GLP-1 → euglycemic DKA — https://pmc.ncbi.nlm.nih.gov/articles/PMC11454998/ Metformin + GLP-1 GI overlap (Diabetes Care) — https://diabetesjournals.org/care/article/47/2/280/153929/ Cannabinoid Hyperemesis Syndrome (StatPearls) — https://www.ncbi.nlm.nih.gov/books/NBK549915/ Sweeteners & gut microbiome (Nature) — https://www.nature.com/articles/nature13793 FDA alert: compounded semaglutide dosing errors — https://www.fda.gov/drugs/human-drug-compounding/fda-alerts-health-care-providers-compounders-and-patients-dosing-errors-associated-compounded Protein + resistance training for muscle preservation (BJSM) — https://pubmed.ncbi.nlm.nih.gov/28698222/ FDA removes GLP-1 suicidality warning — https://www.fda.gov/drugs/drug-safety-communications/fda-requests-removal-suicidal-behavior-and-ideation-warning-glucagon-peptide-1-receptor-agonist-glp Caffeine & gastric acid secretion (PNAS) — https://www.pnas.org/doi/10.1073/pnas.1703728114 FDA kidney injury warning, GLP-1-related dehydration — https://healthesystems.com/workerscomprehensive/fda-requires-new-kidney-injury-warning-for-all-glp-1-drugs/ GLP-1/GIP/glucagon receptor pharmacology (tirzepatide, retatrutide) — https://www.nature.com/articles/s41421-024-00700-0 ⚕️ MEDICAL & EDUCATIONAL DISCLAIMER⚕️ MEDICAL & EDUCATIONAL DISCLAIMER This content is for general educational and informational purposes only and is not medical advice or a substitute for care from your healthcare provider. Viewing this content does not create a doctor-patient relationship with Dr. Mohammed K. Paika. Always consult your healthcare provider before making changes to medications, diet, exercise, or weight-loss treatment, including GLP-1 therapies. Individual risks and results vary.

  • #85
    August 9 · 26 min

    10 Best Foods to Eat on Ozempic, Wegovy, Mounjaro & Zepbound | Doctor Explains

    #GLP1 #Ozempic #Wegovy #Mounjaro #WeightLoss Eating less on Ozempic, Wegovy, Mounjaro, or Zepbound doesn't automatically mean you're eating well. In this video, board-certified Internal Medicine and Obesity Medicine physician Dr. Mohammed Paika breaks down the 10 best foods to eat on a GLP-1 medication — and exactly how they support fat loss, muscle preservation, digestion, and better long-term results from your treatment. You'll learn how GLP-1 and GIP medications actually work in the body, why muscle loss is the risk nobody warns you about, the exact protein targets to hit every day, and the 10 foods — grouped into muscle-protection, gut-protection, and metabolic-health foods — backed by real clinical research. Plus: the biggest myths about these medications, when a GLP-1 should be avoided, the questions to bring to your own doctor, and simple meal templates you can start using today. 📩 Subscribe to our newsletter for weekly evidence-based insights on GLP-1 science, metabolic health, longevity, nutrition, and healthy recipes. You'll also receive a FREE GLP-1 Diet Cookbook, plus access to our complete resource library, including the GLP-1 Masterclass eBook and my books The Physician's Physique and The Weight Equation: https://www.drmohammedpaika.com/newsletter 📘 GLP-1 Masterclass Book (PDF): https://www.drmohammedpaika.com/glp1ebook 🎓 Complete GLP-1 Weight Loss Masterclass (Lifetime Access): Master the science of sustainable weight loss with comprehensive, evidence-based lessons on GLP-1 medications, nutrition, exercise, muscle preservation, side effect management, and long-term success. Your enrollment includes lifetime access, all future video updates at no additional cost, and 6 months of FREE access to the Metabolic Health Community on Skool. https://www.drmohammedpaika.com 👥 Join the Metabolic Health Community on Skool for live Q&As, evidence-based education, accountability, expert support, and a supportive community dedicated to improving metabolic health. Follow Dr. Paika's personal workouts, daily cardio routine, nutrition guidance, and healthy habits in real time, ask questions directly, and connect with others committed to achieving lasting metabolic health. https://www.skool.com/metabolic-health-community-5316 TIMESTAMPS 0:00 Intro – Why "Eating Less" Isn't Enough on a GLP-1 1:48 How GLP-1 & GIP Medications Actually Work 4:18 Why Your Food Choices Matter More Than Ever 6:17 Food #1: Protein (The Non-Negotiable) 9:09 Food #2: Eggs 10:25 Food #3: Oily Fish 11:28 Food #4: Lentils & Beans 13:06 Food #5: Fiber-Rich Vegetables 14:22 Food #6: Kiwifruit 15:41 Food #7: Hydrating Foods & Fluids 17:42 Food #8: Healthy Fats 18:30 Food #9: Greek Yogurt, Cottage Cheese & Skyr 19:20 Food #10: Berries 20:38 Myth vs. Fact 22:21 When to Avoid a GLP-1 Medication 23:06 Questions to Ask Your Doctor 23:38 Simple Meal Templates You Can Start Today 24:30 Final Thoughts + What I'd Watch Next References Wilding JPH, et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. N Engl J Med. 2021;384(11):989–1002. (STEP 1 trial) Jastreboff AM, et al. Tirzepatide Once Weekly for the Treatment of Obesity. N Engl J Med. 2022;387(3):205–216. (SURMOUNT-1 trial) Longland TM, et al. Higher compared with lower dietary protein during an energy deficit combined with intense exercise promotes greater lean mass gain and fat mass loss. Am J Clin Nutr. 2016;103(3):738–746. Ratliff J, et al. Consuming eggs for breakfast influences plasma glucose and ghrelin, while reducing energy intake during the next 24 h period in adult men. Nutr Res. 2010;30(2):96–103. Kim SJ, et al. Effects of dietary pulse consumption on body weight: a systematic review and meta-analysis of randomized controlled trials. Am J Clin Nutr. 2016;103(5):1213–1223. Ha V, et al. Effect of dietary pulse intake on established therapeutic lipid targets for cardiovascular risk reduction. CMAJ. 2014;186(8):E252–E262. Chan AO, et al. Increasing dietary fiber intake in terms of kiwifruit improves constipation in Chinese patients. World J Gastroenterol. 2007;13(35):4771–4775. Rush EC, et al. Kiwifruit promotes laxation in the elderly. Asia Pac J Clin Nutr. 2002;11(2):164–168. Estruch R, et al. Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts. N Engl J Med. 2018;378(25):e34. (PREDIMED) Mozaffarian D, et al. Changes in Diet and Lifestyle and Long-Term Weight Gain in Women and Men. N Engl J Med. 2011;364(25):2392–2404. ⚕️ MEDICAL & EDUCATIONAL DISCLAIMER This content is for general educational and informational purposes only and is not medical advice or a substitute for care from your healthcare provider. Viewing this content does not create a doctor-patient relationship with Dr. Mohammed K. Paika. Always consult your healthcare provider before making changes to medications, diet, exercise, or weight-loss treatment, including GLP-1 therapies. Individual risks and results vary.

  • #84
    August 6 · 26 min

    15 High-Protein Food Swaps for Weight Loss on GLP-1 Medications (Zepbound)

    #GLP1 #Ozempic #wegovy #WeightLoss #HighProteinDiet Eating less on Ozempic, Wegovy, Mounjaro, or Zepbound doesn't automatically mean your diet is helping you lose fat. In this video, hospitalist physician Dr. Mohammed Paika breaks down 15 real grocery-aisle swaps — each evaluated for calories, fat, and carbohydrate quality, not just protein — along with the clinical research on why protein and muscle preservation matter so much while you're on a GLP-1. 0:00 Intro — Why "Eating Less" Isn't Enough on a GLP-1 0:55 Who I Am (Hospitalist Physician, Not an Influencer) 2:40 The Patient I Think About 3:53 Why Protein Isn't Optional on a GLP-1 8:46 15 Swaps: How to Shop Smarter (Start Here) 10:16 Swap 1: Frozen Peas & Corn vs. Edamame 10:52 Swap 2: White Rice vs. Lentils 11:31 Swap 3: Regular Ice Cream vs. High-Protein Ice Cream 12:16 Swap 4: Breaded Chicken Tenders vs. Tempeh 12:47 Swap 5: Granola Bar vs. Protein Bar 13:51 Swap 6: Croutons vs. Roasted Chickpeas 14:28 Swap 7: Mayonnaise vs. Hummus 15:07 Swap 8: Tuna in Oil vs. Tuna in Water 15:44 Swap 9: Breaded Fried Fish vs. Baked Salmon 16:23 Swap 10: Fried Chicken vs. Rotisserie Chicken 16:57 Swap 11: Whole-Milk vs. Part-Skim Mozzarella 17:27 Swap 12: Regular vs. Powdered Peanut Butter 18:13 Swap 13: Whole Milk vs. Ultra-Filtered High-Protein Milk 18:52 Swap 14: Fruit Smoothie vs. Protein Shake 19:39 Swap 15: All-Beef Tacos vs. Turkey & Black Bean Tacos 21:59 Why Muscle Is the Organ of Longevity 📩 Subscribe to our newsletter for weekly evidence-based insights on GLP-1 science, metabolic health, longevity, nutrition, and healthy recipes. You'll also receive a FREE GLP-1 Diet Cookbook, plus access to our complete resource library, including the GLP-1 Masterclass eBook and my books The Physician's Physique and The Weight Equation: https://www.drmohammedpaika.com/newsletter 📘 GLP-1 Masterclass Book (PDF): https://www.drmohammedpaika.com/glp1ebook 🎓 Complete GLP-1 Weight Loss Masterclass (Lifetime Access): Master the science of sustainable weight loss with comprehensive, evidence-based lessons on GLP-1 medications, nutrition, exercise, muscle preservation, side effect management, and long-term success. Your enrollment includes lifetime access, all future video updates at no additional cost, and 6 months of FREE access to the Metabolic Health Community on Skool. https://www.drmohammedpaika.com 👥 Join the Metabolic Health Community on Skool for live Q&As, evidence-based education, accountability, expert support, and a supportive community dedicated to improving metabolic health. Follow Dr. Paika's personal workouts, daily cardio routine, nutrition guidance, and healthy habits in real time, ask questions directly, and connect with others committed to achieving lasting metabolic health. https://www.skool.com/metabolic-health-community-5316 References Look, M., et al. "Body Composition Changes During Weight Reduction with Tirzepatide in the SURMOUNT-1 Study." Diabetes, Obesity and Metabolism, 2025. Neeland, I.J., et al. "Changes in Lean Body Mass with GLP-1-Based Therapies and Mitigation Strategies." Diabetes, Obesity and Metabolism, 2024. The Obesity Society. Clinical guidance on protein intake (1.2–1.6 g/kg/day) during active weight loss. "Higher Protein Intakes Predict Leaner Body Composition in Weight-Loss Participants." International Weight Control Registry, 2024–2025. "Effects of Varying Protein Amounts and Types on Diet-Induced Thermogenesis: A Systematic Review and Meta-Analysis." Leidy, H.J., et al. "Effects of Consuming Frequent, Higher Protein Meals on Appetite and Satiety During Weight Loss in Overweight/Obese Men." Obesity (Silver Spring), 2011. "Dietary Recommendations for the Management of Gastrointestinal Symptoms in Patients Treated with GLP-1 Receptor Agonists." "Clinical Recommendations to Manage Gastrointestinal Adverse Events in Patients Treated with GLP-1 Receptor Agonists: A Multidisciplinary Expert Consensus." Leong, D.P., et al. "Prognostic Value of Grip Strength: Findings from the PURE Study." The Lancet, 2015;386(9990):266–273. "Lean Mass and Musculoskeletal Preservation in GLP-1-Based Obesity Treatment: Nutrition, Exercise, Supplementation, and Monitoring Strategies." 2025. Tinsley, G.M., Nadolsky, S. "Preservation of Lean Soft Tissue During Weight Loss Induced by GLP-1 and GLP-1/GIP Receptor Agonists: A Case Series." 2025. LEAN-PREP Study Protocol: Resistance Exercise and Protein During Semaglutide/Tirzepatide Therapy. ⚕️ MEDICAL & EDUCATIONAL DISCLAIMER This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional. Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

  • #83
    August 4 · 25 min

    10 Mistakes You Must NEVER Make on Ozempic (Or It STOPS Working)

    #Ozempic #GLP1 #WeightLossJourney #ObesityMedicine #semaglutideforweightloss You can be taking Ozempic every week and still stall out — not because the medication stopped working, but because of habits that quietly cancel it out. In this video, Dr. Mohammed Paika (board-certified in Internal Medicine and Obesity Medicine) breaks down the 10 most common mistakes that stall fat loss, cost muscle, and cause GLP-1 side effects — and exactly what to do instead. 📩 Subscribe to our newsletter for weekly evidence-based insights on GLP-1 science, metabolic health, longevity, nutrition, and healthy recipes. You'll also receive a FREE GLP-1 Diet Cookbook, plus access to our complete resource library, including the GLP-1 Masterclass eBook and our books *The Physician's Physique* and *The Weight Equation*: https://www.drmohammedpaika.com/newsletter 📘 GLP-1 Masterclass Book (PDF): https://www.drmohammedpaika.com/glp1ebook 🎓 Complete GLP-1 Weight Loss Masterclass: https://www.drmohammedpaika.com 👥 Join the Metabolic Health Community on Skool for live Q&As, evidence-based education, accountability, expert support, and a community of people committed to improving their metabolic health: https://www.skool.com/metabolic-health-community-5316 TIMESTAMPS 00:00 – Intro: why "it stopped working" is usually the wrong diagnosis 01:52 – How GLP-1 medications actually work 03:48 – Mistake #1: Out-dieting the medication 06:02 – Mistake #2: Letting protein become optional 08:41 – Mistake #3: Skipping resistance training 11:04 – Mistake #4: Letting daily movement quietly disappear 14:04 – Mistake #5: Eating heavy combo meals like nothing changed 15:43 – Mistake #6: Getting dehydrated 17:09 – Mistake #7: Drinking your calories 19:08 – Mistake #8: Using the scale as your only scoreboard 21:02 – Mistake #9: Freestyling your dosing 22:57 – Mistake #10: Injecting the same spot every time 24:17 – Full recap 25:13 – Final thoughts + next steps 👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA Board-Certified in Internal Medicine and Obesity Medicine Certified Personal Trainer & Nutrition Coach Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine. 👍 Like 💬 Comment 📌 Share 🔔 Subscribe for more honest conversations about obesity, metabolism, hormones, and real-world health solutions References Wilding et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1), NEJM 2021 — nejm.org/doi/full/10.1056/NEJMoa2032183 Jastreboff et al. Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1), NEJM 2022 — nejm.org/doi/abs/10.1056/NEJMoa2206038 Lincoff et al. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (SELECT), NEJM 2023 — pubmed.ncbi.nlm.nih.gov/37952131 Neeland et al. Changes in Lean Body Mass with GLP-1-Based Therapies and Mitigation Strategies, Diabetes Obes Metab 2024 — pubmed.ncbi.nlm.nih.gov/38937282 Enhanced Protein Intake on Maintaining Muscle Mass, Strength, and Physical Function in Adults with Overweight/Obesity (meta-analysis) — pmc.ncbi.nlm.nih.gov/articles/PMC8978023 ⚕️ MEDICAL & EDUCATIONAL DISCLAIMER This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional. Viewing this content does not create a doctor-patient relationship between you and Dr. Paika.Health, nutrition, exercise, and medication topics discussed on this channel may not be appropriate for all individuals. Always consult your own healthcare provider before starting or changing any medication, diet, exercise program, or weight-loss plan, including GLP-1 therapies such as Wegovy, Ozempic, Zepbound, Mounjaro, or similar medications. Exercise and lifestyle changes carry inherent risks. By choosing to follow any information from this channel, you accept full responsibility for your health decisions and outcomes. Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

  • #82
    August 1 · 45 min

    Every Peptide & Its Effects Explained

    #Peptides #GLP1 #WeightLoss #ObesityMedicine #longevity Peptides are everywhere online right now, but most videos explain one compound in isolation and skip the actual evidence. In this video, I break down every major peptide people are talking about — repair peptides, growth hormone secretagogues, longevity and immune peptides, hormonal peptides, and the GLP-1 family — with the real human trial data, FDA regulatory status, and honest caveats behind each one. No hype, no fear-mongering — just what the research actually supports. I'm Dr. Mohammed Paika, a hospitalist physician. I see the downstream effects of unmanaged metabolic and hormonal health every day at the bedside, and this video is the same evidence-based breakdown I'd give a patient. What's covered: Repair — BPC-157, TB-500 Growth hormone axis — CJC-1295, Sermorelin, Tesamorelin, Ipamorelin, IGF-1 LR3, Follistatin-344 Aesthetic, immune & longevity — GHK-Cu, Epitalon, Thymosin Alpha-1, MOTS-c Hormonal & quality of life — PT-141, DSIP Metabolic & GLP-1 — AOD-9604, Semaglutide, Tirzepatide, Retatrutide, Cagrilintide Timestamps 0:00 Intro 1:52 Regulatory Reality Check 4:03 Repair Peptides (BPC-157, TB-500) 9:23 Free Resources 10:14 Growth Hormone Axis Peptides 20:43 What's Coming Next 22:13 Aesthetic, Immune & Longevity Peptides 29:49 Hormonal & Quality-of-Life Peptides 32:47 Metabolic & GLP-1 Peptides 42:47 Closing & Next Steps GLP-1 Weight Loss Masterclass - https://www.drmohammedpaika.com Dr. Paika Podcast - https://drmohammedpaika.transistor.fm/ Amazon Kindle - https://www.amazon.it/GLP-1-Masterclass-Physicians-Preservation-Metabolic-ebook/dp/B0GZBR8MC4 👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA Board-Certified in Internal Medicine and Obesity Medicine Certified Personal Trainer & Nutrition Coach Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine. 👍 Like 💬 Comment 📌 Share 🔔 Subscribe for more honest conversations about obesity, metabolism, hormones, and real-world health solutions ⚕️ MEDICAL & EDUCATIONAL DISCLAIMER This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional. Viewing this content does not create a doctor-patient relationship between you and Dr. Paika. Health, nutrition, exercise, and medication topics discussed on this channel may not be appropriate for all individuals. Always consult your own healthcare provider before starting or changing any medication, diet, exercise program, or weight-loss plan, including GLP-1 therapies such as Wegovy, Ozempic, Zepbound, Mounjaro, or similar medications. Exercise and lifestyle changes carry inherent risks. By choosing to follow any information from this channel, you accept full responsibility for your health decisions and outcomes. Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

  • #81
    July 30 · 26 min

    12 Things You Should Avoid Mixing with Ozempic or Mounjaro

    Ozempic #Mounjaro #GLP1 #WeightLoss #ObesityMedicine Some foods, drinks, medications, and supplements can make Ozempic or Mounjaro harder to tolerate — and a few may raise your risk of more serious side effects. If you're dealing with nausea, reflux, constipation, dehydration, or stomach pain, something else in your routine might be making it worse. In this video, board-certified Internal Medicine and Obesity Medicine physician Dr. Mohammed Paika breaks down 12 things to be careful with on Ozempic or Mounjaro — and exactly what to do instead. Drawing on 15+ years as a hospitalist and his own experience with GLP-1 therapy, Dr. Paika walks through the real mechanism behind each risk, the clinical reasoning, and simple fixes you can use starting today. By the end, you'll know what may worsen side effects, what combinations need extra caution, and how to make your GLP-1 treatment safer and easier to stick with. GO DEEPER: 🎓 GLP-1 Masterclass Course — the full physician-built framework for eating, training, and preserving muscle on a GLP-1: https://drmohammedpaika.com 📖 GLP-1 Masterclass Ebook — the same clinical framework, in book form 🍽️ Free GLP-1 Diet Cookbook — join the newsletter at https://drmohammedpaika.com and get it free 📕 The Physician's Physique — Dr. Paika's personal transformation story 📘 The Weight Equation — the deeper clinical science of obesity as a disease 🤝 Metabolic Health Community on Skool — ongoing support and direct access to Dr. Paika TIMESTAMPS: 0:00 – Intro: What This Video Covers 0:54 – Meet Dr. Paika: Why Trust This List 2:48 – #1 Oral Contraceptives 4:16 – #2 Fried & Heavily Breaded Foods 5:55 – #3 Carbonated & Sugary Drinks 7:19 – #4 NSAIDs (Ibuprofen & Naproxen) 8:52 – #5 Oversized Meals 10:21 – #6 Spicy Foods 11:45 – A Quick Word: The GLP-1 Masterclass 12:29 – #7 Alcohol 14:23 – #8 Insulin & Sulfonylureas 15:56 – #9 Fiber & Bulk-Forming Supplements 17:30 – #10 Levothyroxine & Timed Medications 18:54 – #11 Opioids & Sedatives 20:37 – #12 Warfarin 22:06 – The Thyroid Cancer Myth, Explained 23:35 – Final Takeaway 24:24 – How to Go Deeper (Course, Books, Community) 👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA Board-Certified in Internal Medicine and Obesity Medicine Certified Personal Trainer & Nutrition Coach Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine. 👍 Like 💬 Comment 📌 Share 🔔 Subscribe for more honest conversations about obesity, metabolism, hormones, and real-world health solutions ⚕️ MEDICAL & EDUCATIONAL DISCLAIMER This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional. Viewing this content does not create a doctor-patient relationship between you and Dr. Paika. Health, nutrition, exercise, and medication topics discussed on this channel may not be appropriate for all individuals. Always consult your own healthcare provider before starting or changing any medication, diet, exercise program, or weight-loss plan, including GLP-1 therapies such as Wegovy, Ozempic, Zepbound, Mounjaro, or similar medications. Exercise and lifestyle changes carry inherent risks. By choosing to follow any information from this channel, you accept full responsibility for your health decisions and outcomes. Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

  • #80
    July 28 · 34 min

    6 Zepbound Mistakes That Are Ruining Your Results

    #GLP1 #WeightLossJourney #Zepbound #ObesityMedicine #Tirzepatide You can be taking Zepbound exactly as prescribed and still be making mistakes that quietly stall your results. In this video, I break down the 6 most common mistakes I see — as a board-certified internal medicine and obesity medicine physician — that undermine fat loss, muscle preservation, and long-term success on Zepbound, plus two bonus insights most people never hear from their prescriber. These aren't theoretical. They're pulled from my own clinical practice, my patients, and my own two personal body transformations. Want the complete system — deficit strategy, protein targets, training plan, and exit strategy — built by a physician who's lived it? Visit drmohammedpaika.com to enroll in the GLP-1 Masterclass. This video is for educational purposes only and is not a substitute for individualized medical advice from your own physician. Timestamps 0:00 Intro — Why Zepbound Isn't Working the Way You Expected 0:51 Who I Am (And Why This Isn't Just Theory) 1:53 Mistake #1: Staying In a Deficit Too Long 6:22 Mistake #2: Not Drinking Enough Water 9:56 Mistake #3: Not Getting Enough Protein 15:32 Mistake #4: Letting the Medication Do All the Work 20:32 Mistake #5: Obsessing Over the Scale 25:07 Mistake #6: Skipping Strength Training 29:54 Bonus: Sleep, Stress & Cortisol 31:22 Bonus: Advocating For Your Own Pace 32:23 Final Takeaways + Next Steps 📩 Subscribe to our newsletter for weekly evidence-based insights on GLP-1 science, metabolic health, longevity, nutrition, and healthy recipes. You'll also receive a FREE GLP-1 Diet Cookbook, plus access to our complete resource library, including the GLP-1 Masterclass eBook and our books *The Physician's Physique* and *The Weight Equation*: https://www.drmohammedpaika.com/newsletter 📘 GLP-1 Masterclass Book (PDF): https://www.drmohammedpaika.com/glp1ebook 🎓 Complete GLP-1 Weight Loss Masterclass: https://www.drmohammedpaika.com 👥 Join the Metabolic Health Community on Skool for live Q&As, evidence-based education, accountability, expert support, and a community of people committed to improving their metabolic health: https://www.skool.com/metabolic-health-community-5316 👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA Board-Certified in Internal Medicine and Obesity Medicine Certified Personal Trainer & Nutrition Coach Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine. 👍 Like 💬 Comment 📌 Share 🔔 Subscribe for more honest conversations about obesity, metabolism, hormones, and real-world health solutions ⚕️ MEDICAL & EDUCATIONAL DISCLAIMER This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional. Viewing this content does not create a doctor-patient relationship between you and Dr. Paika. Health, nutrition, exercise, and medication topics discussed on this channel may not be appropriate for all individuals. Always consult your own healthcare provider before starting or changing any medication, diet, exercise program, or weight-loss plan, including GLP-1 therapies such as Wegovy, Ozempic, Zepbound, Mounjaro, or similar medications. Exercise and lifestyle changes carry inherent risks. By choosing to follow any information from this channel, you accept full responsibility for your health decisions and outcomes. Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

  • #79
    July 25 · 21 min

    5 Clear Signs Your Metabolism Is Actually Burning Fat

    #Metabolism #FatLoss #GLP1 #WeightLossJourney #obesitymedicine Think a stalled scale means your metabolism has failed you? It probably hasn't — you're just watching the wrong number. In this video, hospitalist physician and exercise scientist Dr. Mohammed Paika breaks down the 5 real, medically-backed signs your metabolism is actually burning fat, why "fast metabolism" is often a myth, and where a lot of popular advice gets the science dangerously wrong (including the real difference between nutritional ketosis and diabetic ketoacidosis). Go deeper at drmohammedpaika.com: → GLP-1 Masterclass (course + e-book) — the full science of satiety and appetite regulation → Free GLP-1 Diet Cookbook — sign up for the newsletter → The Weight Equation — the complete science of obesity medicine → The Physician's Physique — Dr. Paika's personal story TIMESTAMPS 0:00 – The Problem With the Scale 1:04 – Why Listen to Me: Hospitalist 2:38 – Weight Loss Is Not Fat Loss 3:45 – Sign 1: Your Body Fat % Is Dropping 6:54 – Sign 2: Steady Energy & Mental Clarity 10:03 – Sign 3: Your Sugar Cravings Have Quieted Down 13:41 – Sign 4: Satisfied After Meals, Longer Between Them 17:10 – Sign 5: You're Sleeping Deeply 19:12 – Recap + Free Resources 📩 Subscribe to our newsletter for weekly insights on GLP-1 science, metabolic health, longevity, and healthy recipes — plus a free GLP-1 Diet Cookbook when you subscribe: https://www.drmohammedpaika.com/newsletter 📘 GLP-1 Masterclass Book (PDF): https://www.drmohammedpaika.com/glp1ebook 🎓 Complete GLP-1 Weight Loss Masterclass: https://www.drmohammedpaika.com 👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA Board-Certified in Internal Medicine and Obesity Medicine Certified Personal Trainer & Nutrition Coach Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine. 👍 Like 💬 Comment 📌 Share 🔔 Subscribe for more honest conversations about obesity, metabolism, hormones, and real-world health solutions ⚕️ MEDICAL & EDUCATIONAL DISCLAIMER This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional. Viewing this content does not create a doctor-patient relationship between you and Dr. Paika. Health, nutrition, exercise, and medication topics discussed on this channel may not be appropriate for all individuals. Always consult your own healthcare provider before starting or changing any medication, diet, exercise program, or weight-loss plan, including GLP-1 therapies such as Wegovy, Ozempic, Zepbound, Mounjaro, or similar medications. Exercise and lifestyle changes carry inherent risks. By choosing to follow any information from this channel, you accept full responsibility for your health decisions and outcomes. Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

  • #78
    July 23 · 23 min

    Ozempic in the ER: Serious Side Effects of GLP-1 Receptor Agonists

    #Ozempic #GLP1 #Semaglutide #WeightLossJourney #ObesityMedicine Most Ozempic and Mounjaro side effects are just uncomfortable — but a few can land you in the ER. In this video, Dr. Mohammed Paika (board-certified internal medicine + obesity medicine physician, 15+ years as a hospitalist) breaks down which GLP-1 side effects are genuinely dangerous, who's at higher risk, and the exact red-flag symptoms you should never wait out. What's covered: Why GLP-1 side effects happen (the mechanism in plain terms) Nausea/vomiting: normal vs. red flag Dehydration and acute kidney injury DKA risk for diabetics on GLP-1s Gallbladder disease and pancreatitis Gastroparesis, explained without the internet hype The thyroid cancer warning — what the label actually means Muscle loss: the side effect no one talks about (and how to prevent it) Mood changes and when to get help A full red-flag quick-reference recap This video is for education, not medical advice — always talk to your own prescriber about your specific situation. Want the full system for nutrition, protein targets, training, and side-effect management on GLP-1 medications? Join the GLP-1 Masterclass at https://drmohammedpaika.com If this helped, subscribe for the next video on structuring protein and training week-by-week on these medications. If you or someone you know is struggling with thoughts of self-harm, call or text 988 (Suicide & Crisis Lifeline). GLP-1 Weight Loss Masterclass - https://www.drmohammedpaika.com Dr. Paika Podcast - https://drmohammedpaika.transistor.fm/ Amazon Kindle - https://www.amazon.it/GLP-1-Masterclass-Physicians-Preservation-Metabolic-ebook/dp/B0GZBR8MC4 Timestamps 0:00 Intro 0:49 Who I Am 2:58 Why GLP-1 Side Effects Happen 3:57 Nausea & Vomiting: Where It Usually Starts 5:05 Dehydration & Acute Kidney Injury 7:41 Starvation Ketosis & DKA Risk 9:37 Quick Note: GLP-1 Masterclass 10:17 Gallbladder Disease & Pancreatitis 12:35 Gastroparesis: The Internet-Famous One 14:01 The Thyroid Cancer Myth 15:55 Muscle Wasting: The One I See Most Often 19:13 Mood Changes & Depression 21:01 Who Is At Higher Risk: The Summary 21:59 The Red Flags: Quick Recap 22:43 Close & Next Steps References: FDA Prescribing Information — Ozempic (semaglutide): [accessdata.fda.gov label](https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/209637s020s021lbl.pdf) FDA Prescribing Information — Mounjaro (tirzepatide): [accessdata.fda.gov label](https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/215866s039lbl.pdf) FDA Prescribing Information — Zepbound (tirzepatide): [accessdata.fda.gov label](https://www.accessdata.fda.gov/drugsatfda_docs/label/2026/217806s042lbl.pdf) (Wegovy shares the same active ingredient, semaglutide, and labeling basis as Ozempic.) Wilding JPH, et al. STEP 1 body composition sub-study — DEXA data on fat vs. lean mass loss: [J Endocr Soc](https://academic.oup.com/jes/article/5/Supplement_1/A16/6240360) Look M, et al. SURMOUNT-1 body composition sub-study — lean mass findings on tirzepatide: [Diabetes Obes Metab, 2025](https://dom-pubs.onlinelibrary.wiley.com/doi/10.1111/dom.16275) Bjerre Knudsen L, et al. Endocrinology 2010;151(4):1473-1486 — the rodent thyroid C-cell study behind the boxed warning: [Oxford Academic](https://academic.oup.com/endo/article/151/4/1473/2456651) 👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA Board-Certified in Internal Medicine and Obesity Medicine Certified Personal Trainer & Nutrition Coach Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine. 👍 Like 💬 Comment 📌 Share 🔔 Subscribe for more honest conversations about obesity, metabolism, hormones, and real-world health solutions ⚕️ MEDICAL & EDUCATIONAL DISCLAIMER This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional. Viewing this content does not create a doctor-patient relationship between you and Dr. Paika. Health, nutrition, exercise, and medication topics discussed on this channel may not be appropriate for all individuals. Always consult your own healthcare provider before starting or changing any medication, diet, exercise program, or weight-loss plan, including GLP-1 therapies such as Wegovy, Ozempic, Zepbound, Mounjaro, or similar medications. Exercise and lifestyle changes carry inherent risks. By choosing to follow any information from this channel, you accept full responsibility for your health decisions and outcomes. Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

  • #77
    July 21 · 35 min

    Anti-Aging and Longevity Habits for More Energy, Better Blood Work, & a Longer Life

    #Longevity #AntiAging #GLP1 #MetabolicHealth #Biohacking You don't need a complicated longevity routine to start aging better — you need to know which habits actually move the needle. In this video, hospitalist and obesity medicine physician Dr. Mohammed Paika breaks down the evidence-based habits, blood work targets, and training principles that drive real energy, better labs, and a longer, stronger life. In this video, you'll learn: - The four free daily habits — grounding, breathwork, morning sunlight, and cold exposure — and the research behind each one - The truth about cholesterol, triglycerides, and statins (and why one number on your lab report isn't the whole story) - Why food quality matters more than which diet you follow, including an honest look at seed oils and GMOs - Why muscle is your most powerful longevity organ, and the two benchmarks proven to predict how long you'll live - The exact annual blood panel to ask your doctor for - How all of this connects to metabolic health and GLP-1 medications 📩 Subscribe to our newsletter for weekly insights on GLP-1 science, metabolic health, longevity, and healthy recipes — plus a free GLP-1 Diet Cookbook when you subscribe: https://www.drmohammedpaika.com/newsletter 📘 GLP-1 Masterclass Book (PDF): https://www.drmohammedpaika.com/glp1ebook 🎓 Complete GLP-1 Weight Loss Masterclass: https://www.drmohammedpaika.com Timestamps 0:00 Intro — Why Habits Matter More Than Trends 0:58 Why I'm Qualified to Tell You This 2:12 Aging Is a Life Engineered for Comfort 4:20 Habit 1 — Grounding 6:22 Habit 2 — Breathwork 8:54 Free Newsletter + GLP-1 Cookbook 9:39 Habit 3 — Sunlight & Vitamin D 12:01 Habit 4 — Cold Exposure & Hormesis 14:34 The Truth About Cholesterol, Triglycerides & Statins 19:45 Food Quality — Seed Oils, GMOs & B12 24:10 Muscle — Your Most Powerful Longevity Organ 28:32 The Annual Blood Work You Need 30:57 How This Connects to GLP-1s & Weight Loss 32:22 Your Daily & Weekly Protocol 33:32 What to Do Next 👨‍⚕️ ABOUT DR. MOHAMMED K. PAIKA Board-Certified in Internal Medicine and Obesity Medicine Certified Personal Trainer & Nutrition Coach Helping people understand metabolism, hormones, and sustainable health through evidence-based medicine. 🔔 Subscribe for more honest conversations about obesity, metabolism, hormones, and real-world health solutions References 1. NHLBI ATP III — nhlbi.nih.gov/files/docs/guidelines/atp3xsum.pdf 2. Harvard Health — health.harvard.edu/heart-health/how-its-made-cholesterol-production-in-your-body 3. Krauss, Circulation — ahajournals.org/doi/10.1161/01.cir.0000033222.75187.b9 4. Insulin/Lipolysis — pmc.ncbi.nlm.nih.gov/articles/PMC7227813 5. NTP Fluoride 2024 — ntp.niehs.nih.gov/publications/monographs/mgraph08 6. FWW v. EPA — foodandwaterwatch.org/2024/09/25/historic-court-decision-in-fluoridation-toxicity-case-orders-epa-to-act 7. Natl. Academies GMO — nap.nationalacademies.org/read/23395 8. Leong, Lancet 2015 — thelancet.com/journals/lancet/article/PIIS0140-6736(14)62000-6/abstract 9. Momma, BJSM 2022 — pubmed.ncbi.nlm.nih.gov/35228201 10. Kox, PNAS 2014 — pnas.org/doi/10.1073/pnas.1322174111 11. van Marken Lichtenbelt, NEJM — nejm.org/doi/full/10.1056/NEJMoa0808718 12. Sacks, Circulation 2017 — ahajournals.org/doi/pdf/10.1161/cir.0000000000000510 13. NIH ODS Vitamin D — ods.od.nih.gov/factsheets/VitaminD-HealthProfessional 14. StatPearls Testosterone — ncbi.nlm.nih.gov/books/NBK526128 15. Cleveland Clinic Sarcopenia — my.clevelandclinic.org/health/diseases/23167-sarcopenia 16. Attia, Outlive — peterattiamd.com/outlive 17. Marchand Case Study — foreverfitscience.com/research/breaking-records-and-barriers-robert-marchand 18. Chevalier 2012 — pmc.ncbi.nlm.nih.gov/articles/PMC3265077 19. Simmons Podcast — theringer.com/2016/06/08/nba/nba-lebron-james-bill-simmons-malcolm-gladwell-5369d6959c67 ⚕️ MEDICAL & EDUCATIONAL DISCLAIMER This channel and its content are provided by Dr. Mohammed K. Paika, MD for general educational and informational purposes only. The information presented is not intended as medical advice and does not replace consultation with your personal physician or qualified healthcare professional. Viewing this content does not create a doctor-patient relationship between you and Dr. Paika. Health, nutrition, exercise, and medication topics discussed on this channel may not be appropriate for all individuals. Always consult your own healthcare provider before starting or changing any medication, diet, exercise program, or weight-loss plan, including GLP-1 therapies such as Wegovy, Ozempic, Zepbound, Mounjaro, or similar medications. Exercise and lifestyle changes carry inherent risks. By choosing to follow any information from this channel, you accept full responsibility for your health decisions and outcomes. Dr. Paika and affiliated entities disclaim any liability for injuries, adverse effects, or damages resulting from use or application of information presented in this content.

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