BoB In South Florida: Anthony Japour, M.D., iTolerance
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On this week's episode of the Business of Biotech -- part three in a four part series recorded in-person at Catalyst Pharmaceuticals' Miami headquarters -- Anthony Japour, M.D., CEO at iTolerance, talks about his work as a physician treating infectious diseases, his CEO role in diagnostics at the height of the COVID-19 pandemic, what he learned working as a medical director at a large CRO, and iTolerance's work toward a cure for Type 1 diabetes that doesn't require chronic immunosuppression. Anthony also provides insights on overcoming CMC challenges and how to bypass avoidable detours, the funding climate for preclinical biotechs, and operating in South Florida.
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- 0:07Opening & Guest Introduction
- 0:21Anthony’s Background and Career Arc
- 3:49Lessons from CROs and Service Models
- 6:03Leading a COVID Diagnostics Company
- 9:13Europe vs US: EUA and LDT Frictions
- 11:01Path to iTolerance and NHP Data
- 13:47Why Immunosuppression Is the Bottleneck
- 16:21Cadaveric Islets, Regulation, and Access
- 19:06Timelines to a Type 1 Diabetes Cure
- 22:18Inside iTolerance’s Pipeline and Strategy
- 24:08Funding, CMC Pivots, and Runway
- 28:38Manufacturing Lessons: From E. coli to Insect Cells
- 31:05Leading in South Florida & Personal Resilience
- 33:02Closing Thoughts & Subscribe