Using Genetics To Discover New Treatments With Regeneron Genetics Center's Aris Baras, M.D.
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On this week's episode of the Business of Biotech, Aris Baras, M.D., SVP, Head of Regeneron Genetics Center (RGC) and Co-Head of Regeneron Genetic Medicines, talks about using large-scale human genetics to find better drug targets based on "superhuman" variants. Aris explains how multi-omics, linked health records, and AI are helping developers move faster in the clinic and reduce the odds of failure, while also pushing biotech toward earlier disease prediction and more preventive care.
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- 0:00Welcome And Guest Overview
- 1:30Aris Baras Career Detours
- 5:09Why Regeneron Built The RGC
- 8:27PCSK9 And The Superhuman Idea
- 12:18Genetic Diversity And Global Partners
- 16:15From 3 Million To Everyone Sequenced
- 20:17Exomes Versus Genomes Plus Proteomics
- 26:51Health Records Tokenization And Scale
- 41:22How AI Helps Find Signals
- 45:45Free Gene Therapy And Rare Disease Math
- 51:01The Two Year And Ten Year Vision