Two Onc Docs

Sam and Karine

This is Sam and Karine, and we are Two Onc Docs! We both graduated from our Heme/Onc fellowships in 2021 and became board certified in both Hematology and Oncology. Our mission with Two Onc Docs is to create short board review episodes that you can listen to on your drive to work, while you make your morning coffee, or between pages on call. This is intended to be a supplement to other established board studying resources for busy trainees. *This podcast is intended to be an educational resource for health care providers.*

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23 episodes
weekly
Avg 16 min
English

Episodes 23

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Today · 13 min
Non-Small Cell Lung Cancer 2026 UPDATE
This week's episode focuses on early-stage and locally advanced non-small cell lung cancer - staging, pathology, local and systemic therapy. Before we start, the usual caveat: the treatment landscape of NSCLC is changing FAST, which is exciting, but know that the boards run a few years behind. The big shifts since our last episode are the move to 9th-edition TNM staging and the arrival of four different perioperative chemo+immunotherapy regimens. Shout out to Dr. Bharathi Muthusamy for reviewing this episode to keep us current for 2026!
August 24 · 10 min
Myelodysplastic Syndrome (MDS) 2026 UPDATE
Today’s episode is focusing on what you need to know regarding myelodysplastic syndrome (MDS). This will include the high yield facts on risk factors, diagnostic work-up, staging and treatment of MDS, we were overdue do this this topic, last done in 2022.
August 17 · 22 min
Iron Overload 2026 UPDATE
This week’s episode will be focusing on syndromes of iron overload. We will go over all important details on hemochromatosis and other related diseases. We last covered this topic in 2023.
August 3 · 14 min
How to Approach a New Malignancy 101
This week’s episode will be focusing on how to approach a newly diagnosed malignancy, biopsy, staging, patient considerations ect.
July 28 · 17 min
Tips for Heme/Onc Fellowship 2026
This week’s episode will be focusing on how to transition well into heme/onc fellowship including differences from residency, tips for surviving, wellness, resources & more.
July 20 · 12 min
DLBCL 2026 UPDATE
This week’s episode will be focusing on Diffuse Large B-Cell Lymphoma (DLBCL). We will go all the important details on this aggressive NHL which can be highly curable. We have some new changes since we last covered this topic in 2022 including a new category 1 option for advanced DLBCL
July 13 · 23 min
Wellness in Oncology with Dr. Laura Vater
This week’s episode we are back with our very special guest, friend and colleague Dr Laura Vater joining us to talk about wellness in oncology, and burnout prevention tips.
June 29 · 19 min
Transitioning from Fellow to Attending with Dr. Laura Vater
This week’s episode we have a very special guest, friend and colleague Dr. Laura Vater joining us to talk about one of the biggest transitions in medicine—moving from fellow to attending. Dr Vater is a GI oncologist at IU, writer, and speaker. She focuses on the dignity of patients and clinicians, and strives to keep healthcare human.
S5 · E9
June 22 · 11 min
ASCO 2026 Plenary: SARC-041
This week’s episode will be focusing on an ASCO 2026 Plenary abstract, SARC 041. SARC041 is the first positive phase 3 randomized controlled trial of a CDK4/6 inhibitor in advanced dedifferentiated liposarcoma (DDLPS), demonstrating that abemaciclib significantly improves progression-free survival compared to placebo.
S5 · E8
June 15 · 14 min
ASCO Annual Meeting 2026 GU Recap
Today we are recapping exciting GU data presented at the 2026 ASCO Annual Meeting in bladder cancer, kidney cancer, and prostate cancer.
S5 · E7
June 8 · 11 min
ASCO 2026 Plenary: RASolute-302
This week’s episode will be focusing on the 2026 ASCO Plenary that received a standing ovation, the RASolute 302 trial. The RASolute 302 trial is a landmark phase 3 study demonstrating that daraxonrasib doubled overall survival compared to chemotherapy in previously treated (2L) metastatic pancreatic ductal adenocarcinoma (mPDAC).
S5 · E6
May 25 · 11 min
ASCO Annual Meeting 2026 Preview
Today we will be focusing on exciting data to come at the ASCO Annual Meeting in 2026 in Chicago, with a special focus on GU sessions, educational sessions & med ed sessions.
S5 · E5
May 18 · 13 min
Von Willebrand Disease (VWD) 2026 UPDATE
This week’s episode will be focusing on Von Willebrand disease (VWD), a highly testable bleeding disorder. We will go over all the important details on the diagnosis, types of VWD as well as treatment.
S5 · E4
May 11 · 11 min
Aplastic Anemia 2026 UPDATE
Today’s episode is focusing on the highest yield facts about Aplastic Anemia. This will include the mechanism of AA, diagnostic work-up, treatment of AA, and the evolution of clones including PNH.
S5 · E3
May 4 · 9 min
Metastatic Bladder Cancer 2026 UPDATE
Today’s episode is focusing on what you need to know regarding metastatic bladder cancer, with 2026 updates. This will include the need to know treatment options and toxicities for metastatic urothelial carcinoma, and also discuss the management of upper tract + variant non-urothelial histology.
S5 · E2
April 27 · 13 min
Localized Bladder Cancer 2026 UPDATE
Today’s episode is focusing on what you need to know regarding localized bladder cancer, with 2026 updates. This will include the need to know pathology, presentation, diagnostic work-up, staging, and treatment options.
S5 · E1
April 20 · 12 min
4 Years with Two Onc Docs
This week’s episode will be focusing on how we met, the future of the podcast, and why we picked heme/onc. This is a very different style of episode and a special once because this month is our 4 year anniversary of Two Onc Docs! And we will back to our regular programming next week with overdue updates on Bladder Cancer.
April 13 · 14 min
Pancreatic Cancer x Dr. Michael Pishvaian 2026 UPDATE Part 3
We are back with a very special guest Dr. Michael Pishvaian, who is an Associate Professor in GI Oncology at the Johns Hopkins Kimmel Cancer Center, and creator of Tumor Board Tuesday. In part 3, we discuss supportive care in pancreatic cancer, and exciting trials in this space.
April 6 · 25 min
Metastatic Pancreatic Cancer x Dr. Michael Pishvaian 2026 UPDATE Part 2
We are back with a very special guest Dr. Michael Pishvaian, who is an Associate Professor in GI Oncology at the Johns Hopkins Kimmel Cancer Center, and creator of Tumor Board Tuesday. In part 2, we will focus on metastatic pancreatic cancer, 1L treatments, maintenance therapy, targeted therapy + more.
March 30 · 37 min
Localized Pancreatic Cancer x Dr. Michael Pishvaian 2026 UPDATE Part 1
This week’s episode will be discussing Pancreatic Cancer with a very special guest Dr. Michael Pishvaian. Dr. Pishvaian is an Associate Professor in GI Oncology at the Johns Hopkins Kimmel Cancer Center, and creator of Tumor Board Tuesday. In part 1, we will focus on risk factors, diagnosis and treatment of localized pancreatic cancer.

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