Tiny Matters

Multitude

Science shapes every facet of our lives, but so much of its influence is overlooked or buried in the past. Tiny Matters is an award-winning science podcast about the small science of big things. From the microbes behind deadly diseases to the molecules informing our search for extraterrestrial life, hosts and former scientists Sam Jones and Deboki Chakravarti embrace the awe and messiness of science and its significance both today and in the past, asking questions like, "how was IVF invented?," "what do glaciers tell us about Earth’s ancient past?," and "why is smallpox the only human infectious disease we’ve eradicated?"

Tiny Matters is created by the American Chemical Society, a non-profit scientific organization based in Washington, D.C., and is produced by Multitude. New episodes every Wednesday, wherever you listen to podcasts.

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183 episodes
Updated Wednesday

Episodes183

Newest first

April 1 · 42 min
Stinky white gold, Haber-Bosch, and ‘peecycling’: How fertilizer shapes our world
Fertilizer… boring? Not on our watch! In this episode of Tiny Matters, we trace the history of fertilizer from the ‘Guano Wars’ to the invention of the Haber-Bosch process, one of the most impactful chemical breakthroughs in human history. Today, scientists and communities are rethinking how we handle nutrients, and asking: could our own urine help close the nutrient loop? We chat with chemist Leila Duman about why nitrogen is so hard to “fix,” how industrial fertilizer feeds billions (while unfortunately polluting waterways), and why the Haber-Bosch process is still essentially perfect. Then we head to Vermont’s Rich Earth Institute, where researchers are turning human urine into safe, effective fertilizer and reimagining waste as a resource. Check out Pale Blue pod! Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter! All Tiny Matters transcripts and references are available here. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
March 25 · 19 min
[BONUS] Reef balls and peanut allergy immunotherapy: Tiny Show and Tell Us #43
In this episode of Tiny Show and Tell Us, we explore a listener's experience with peanut allergy immunotherapy — what it is, how the therapy works, and the odd and fascinating history of allergy treatments, including a 19th‑century scientist who shoved grass pollen up his own nose. Then we chat about “reef balls” made of oyster shells and concrete. These mini artificial reefs are being used to restore marine habitats and, in some cases, also hold cremated remains. Check out Simple and Clean here or wherever you listen to podcasts! We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured. A transcript and references for this episode can be found at acs.org/tinymatters. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
March 18 · 1 hr 21 min
The Mothers of Gynecology: The centuries that led to today’s Black maternal mortality crisis
In this special crossover episode, Tiny Matters welcomes Alexis Pedrick, host of Distillations from the Science History Institute. You’ll hear the Distillations episode “The Mothers of Gynecology” — a powerful investigation into the racist origins of gynecology and the ongoing maternal health care crisis that disproportionately affects Black mothers. Through interviews with historians, clinicians, midwives, doulas, and public health researchers, the episode traces how racist myths about Black bodies — especially beliefs about pain tolerance — continue to shape medical care and outcomes. Following the episode, we unpack some of what you’ll hear, from the horrific exploitation of enslaved women by J. Marion Sims, to modern-day disparities that affect even the wealthiest, most famous Black mothers, including Beyoncé and Serena Williams. Check out Spirits here or wherever you listen to podcasts. Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter! All Tiny Matters transcripts and references are available here. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
March 13 · 8 min
A new podcast joining the fam: Chain Reaction by ACS!
Chain Reaction is a new podcast from the American Chemical Society that links chemistry’s past to its future, revealing how this ever‑evolving science shapes the world around us, from the materials we use every day to the environment that we depend on. Each episode brings fresh perspectives and personal stories from chemists, engineers, and other scientists, as well as historians who guide us through pivotal moments in chemistry’s history. Together, we’ll uncover chemistry’s surprising connections, explore its interdisciplinary impact, and see how past discoveries set off the breakthroughs of today and the future. Whether you’re a student, an experienced scientist, or simply curious, Chain Reaction will show you how chemistry fits into the bigger picture — and why it matters now more than ever. Subscribe wherever you listen to podcasts! acs.org/chainreaction Exec producer: Sam Jones Producer: Margot Wohl Researcher: Bec Roldan Production support: Michael David and Matthew Radcliff Cover art: Joe Butera See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
March 11 · 16 min
[BONUS] 5D storage in the ‘Memory of Mankind’ and the root of morning sickness: Tiny Show and Tell Us #42
In this episode of Tiny Show and Tell Us, we go from nerdy house-party physics to the brutal realities of morning sickness (can you say range!). First, we unpack what 5D data storage is and debate what we’d personally toss into the “Memory of Mankind” salt mine in Austria. Then we tackle a listener’s question about whether science has any updates on what causes severe morning sickness. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured. A transcript and references for this episode can be found at acs.org/tinymatters. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
March 4 · 47 min
Inside expedition medicine: Keeping people alive in the harshest places on Earth
In 2019, Nathan Hudson-Peacock was serving as an expedition doctor to a group hiking in the Indian Himalayas. At around 17,000 feet, a climber suddenly went from having a mild headache to a life‑threatening cerebral edema. On top of that, a storm was closing in. So, what did he do? How do expedition doctors keep people alive in the harshest places on Earth? Tune in to this week’s episode to find out. In it, we chat with Nathan as well as high altitude physician Monica Piris, who has spent much of her time on Everest. We dig into the world of expedition medicine: the preparation, the danger, the breathtaking environments, and the moments that can reshape your understanding of the planet and the impact of climate change. Listen to American Medieval: https://americanmedieval.com/ Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter! All Tiny Matters transcripts and references are available here. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
February 25 · 15 min
[BONUS] 'Mitochondrial Eve' and birds stealing anti-bird spikes: Tiny Show and Tell Us #41
In this episode of Tiny Show and Tell Us, we talk about the crafty corvids that steal anti‑bird spikes to build chaotic, spiky nests and “Mitochondrial Eve” — the most recent common maternal ancestor of modern humans. Get ready for stories of sandwich‑stealing gulls, Deboki being held hostage by a peacock, and the Mitochondrial Eve/Y Chromosomal Adam romcom no one asked for. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured. A transcript and references for this episode can be found at acs.org/tinymatters. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
February 18 · 37 min
From ancient grain mills to massive offshore turbines: Why wind energy was — and still is — a big deal
For over a thousand years, humans have been harnessing wind energy. It may have begun with small, grain‑grinding windmills in ancient Persia, but today you might spot Hoover‑Dam‑sized offshore turbines as you drive along the east coast. How did we get here? In this episode of Tiny Matters, we explore the first electric wind turbines built in the late 1800s, how government policies in the 1970s and ’80s shaped the modern wind industry, and why giant offshore wind farms are suddenly in the news. We also clear up misinformation stemming from a Hollywood blockbuster as well as what we know about the impact of wind farms on whales, birds and bats. Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter! All Tiny Matters transcripts and references are available here. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
February 11 · 13 min
[BONUS] Dandelion rubber tires and a fentanyl vaccine: Tiny Show and Tell Us #40
In this episode of Tiny Show and Tell Us, we explore a listener’s tip about a new source of tire rubber — the Russian dandelion — and the science behind what makes it such an incredible and sustainable source of natural latex rubber. Then we answer a listener’s question about a vaccine for fentanyl that will stop the drug from reaching the brain, preventing overdose. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured. A transcript and references for this episode can be found at acs.org/tinymatters. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
February 4 · 36 min
The history of clinical trials: From fake exorcisms to testing today
In 1599, a family in a small French town claimed that their daughter was possessed by a demon called Beelzebub and, despite daily exorcisms, the demon possessing this woman was staying put. So France’s Henri IV set up a royal commission that would try something a little different. The woman would still receive exorcisms, complete with the normal exorcism accoutrements, but with a catch. The priest wouldn’t actually be Catholic, the water in the vessel would be ordinary water, and the Latin used wouldn’t be religious — it would be from Virgil’s famous poem Aeneid. That's because this wasn't actually an exorcism. It was an experiment built on a deceptively simple tool that scientists and doctors still use today to study new medical treatments: a placebo. In this episode, we explore the surprising origins and evolution of one of modern medicine’s most important tools: the clinical trial. We follow the development of experimental design across centuries to modern day randomized controlled trials and the debates about their limitations, trying to answer the question, “How do we know whether a treatment truly works?” Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter! All Tiny Matters transcripts and references are available here. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
January 28 · 14 min
[BONUS] Bat periods and toxins from fungi: Tiny Show and Tell Us #39
In this episode of Tiny Show and Tell Us, we learn that humans aren’t the only mammals who menstruate. We explore the fulvous fruit bat’s 33‑day cycle, how reproductive biology differs across species, and why scientists still don’t fully understand why menstruation evolved in the first place. Then we take a deep dive into the world of mycotoxins: dangerous compounds produced by fungi. We cover how these toxins form, why they’re so hard to eliminate, and risks they pose to agriculture, livestock, and human health. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured. A transcript and references for this episode can be found at acs.org/tinymatters. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
January 21 · 41 min
The iron lung: How a hulking metal tube became the first machine to keep humans alive
It’s no exaggeration to say that polio shaped modern medicine. Before a vaccine was available, polio outbreaks left thousands of people paralyzed, with some unable to breathe. But, in 1928, the development of the iron lung meant that, for the first time, humans could rely on a machine to stay alive. In this episode, we trace the rise of polio in the early 20th century, the science behind the virus, and the race to save lives. From early resuscitation experiments to the unexpected inspiration behind the iron lung, we uncover the innovation, ethical dilemmas, and human stories that defined this era, hearing from two people whose early childhoods and families were dramatically shaped by the disease. Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter! All Tiny Matters transcripts and references are available here. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Dec 31, 2025 · 14 min
[BONUS] The woman who mapped the Milky Way and a toxic evolutionary showdown: Tiny Show and Tell Us #38
In this episode of Tiny Show and Tell Us, we kick things off with a quick shout-out to a listener who started flossing thanks to a previous episode. Then we dive into the hidden history of the women “computers” at Harvard Observatory, including Henrietta Leavitt, who laid the foundation for modern astronomy with her groundbreaking discoveries including calculating the size of the Milky Way. Then we discuss the co-evolutionary arms race between passion vines and Heliconius butterflies, which includes fake eggs, toxic fruit, and impaled caterpillars. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured. A transcript and references for this episode can be found at acs.org/tinymatters. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Dec 24, 2025 · 51 min
Sam’s brain-altering bacteria and Deboki’s polio vaccine fascination: EPISODE 100!
In this milestone 100th episode of Tiny Matters we take you on a personal journey into what first inspired our passion for science. Sam shares the story of her childhood struggle with germophobia and the brain-altering bacteria that kicked it off, likely causing a condition called PANDAS: Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections. PANDAS may have led to her OCD, but it also fueled Sam’s fascination with the microscopic world, germ theory, and the ways infections can shape our brains. Then Deboki dives into her early fascination with vaccines, inspired by the interests of her scientist parents. She shares the history of the polio vaccine — a story of victory but also tragedy that led to significant progress, both in terms of science and safety. Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter! All Tiny Matters transcripts and references are available here. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Dec 17, 2025 · 22 min
[BONUS] Bunny pregnancy tests and a dead salmon MRI: Tiny Show and Tell Us #37
In this episode of Tiny Show and Tell Us, we read an email from “baby sis” aka Binky aka Sam’s younger sister Caroline who writes in about an alarming pregnancy test that predates today’s at-home tests. Then we talk about a fascinating study that found a dead salmon showed brain activity in an MRI machine. Spoiler: It wasn’t actually alive, scientists just really needed to rethink MRI analysis. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured. A transcript and references for this episode can be found at acs.org/tinymatters. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Dec 10, 2025 · 37 min
How life keeps time: Zeitgebers, hidden clocks, and ugh daylight saving
Not a fan of daylight saving? Beyond the depressingly early sunsets, that may be because it’s messing with your circadian clock. In this episode of Tiny Matters, we ask, “How do organisms — from bacteria to sea anemones to humans — keep track of time?” We talk about circadian clocks and how both internal molecular changes and environmental cues called “zeitgebers,” which include things like light and food, synchronize biological rhythms and help all of us survive. Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter! All Tiny Matters transcripts and references are available here. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Dec 3, 2025 · 14 min
[BONUS] Polar bear fact vindication and vibrating insects: Tiny Show and Tell Us #36
In this episode of Tiny Show and Tell Us, we read an email from a listener who, as a kid, shared a fun fact with her classroom: polar bears have black skin. Her teacher not only told her she was wrong but embarrassed her in front of the other students. Well, it’s time to set the record straight. Polar bears do, in fact, have black skin and we do, in fact, love a grudge and are so glad to provide vindication. Then we talk about the hidden world of insect vibrational communication. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured. A transcript and references for this episode can be found at acs.org/tinymatters. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Nov 26, 2025 · 36 min
Dinner with King Tut: How experimental archaeologists are recreating the past
In today’s episode, we chat with author Sam Kean about his new book Dinner with King Tut and learn how researchers and citizen scientists are recreating ancient recipes, tools, and technologies — from wound remedies with pennies to inventive pottery glazed in blood — and how experimental archaeology is changing our understanding of the past. Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter! All Tiny Matters transcripts and references are available here. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Nov 19, 2025 · 15 min
[BONUS] Making magenta pennies and touching the sun: Tiny Show and Tell Us #35
In this episode of Tiny Show and Tell Us, we talk about different ways of turning pennies all of the colors of the rainbow. Then we discuss an ongoing NASA mission to touch the sun. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured. A transcript and references for this episode can be found at acs.org/tinymatters. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Nov 12, 2025 · 33 min
What's eating the Titanic?
Most of us know the story of the Titanic. In 1912, the massive — supposedly indestructible — steamship sank after hitting an iceberg on its first and only journey across the Atlantic Ocean. Titanic remained undiscovered on the seafloor, somewhere in the North Atlantic Ocean, for 73 years, until it was found nearly two miles beneath the surface. But now the ship might be disappearing again, this time for good. And the culprit is not another iceberg — it’s something much, much smaller. Send us your science facts, news, or other stories for a chance to be featured on an upcoming Tiny Show and Tell Us bonus episode. And, while you're at it, subscribe to our newsletter! All Tiny Matters transcripts and references are available here. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.