The Big Unlock

Rohit Mahajan & Ritu M. Uberoy

THE BIG UNLOCK PODCAST is a Healthcare Digital Transformation Podcast. Stay Updated on Healthcare’s Digital Transformation Trends. Featuring C-suite Leaders and Insights on Digital Health Innovation. Explore Emerging Healthcare Technologies with Rohit Mahajan and Ritu M. Uberoy.

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20 episodes
Updated Tuesday

Episodes20

Newest first

Tuesday · 22 min
Episode 219 – Health Literacy is Key to Better Patient Outcomes
The Big Unlock · Greg O’Neill, Director, Patient & Family Health Education, ChristianaCare In this episode, Greg O’Neill, Director of Patient & Family Health Education at ChristianaCare, explores why effective communication is one of the mo
July 28 · 23 min
Episode 218 – Using Multimodal Foundations and Ambient AI to Scale Clinical Impact
The Big Unlock · Umesh Rustogi, General Manager, HLS Dragon & Platform, Microsoft In this episode, Umesh Rustogi, General Manager, Healthcare & Life Sciences Dragon & Platform at Microsoft, explains that meaningful AI outcomes depend on combi
July 21 · 25 min
Episode 217 – Building Trust in the Next Generation of Healthcare AI
The Big Unlock · Dr. Haider Warraich, Program Manager, Scalable Solutions, ARPA-H In this episode, Dr. Haider Warraich, Program Manager, Scalable Solutions at Advanced Research Projects Agency for Health (ARPA-H), explains why building trust, not just ad
July 13 · 25 min
Episode 216 – The Future of Healthcare Lies in Connected, Evidence-Based Systems
The Big Unlock · Dr. Anne Snowdon, Scientific Director and CEO, SCAN Health and Chief Scientific Research Officer, HIMSS In this episode, Dr. Anne Snowdon, Scientific Director and CEO at SCAN Health and Chief Scientific Research Officer at HIMSS, explore
July 6 · 24 min
Episode 215 – Bridging Pharma and Startups to Scale Digital Health Innovation
The Big Unlock · Naomi Fried, PhD, Founder and CEO, PharmStars In this episode, Naomi Fried, PhD, Founder and CEO of PharmStars, shares how stronger collaboration between startups and pharmaceutical companies is accelerating healthcare innovation. Drawin
June 29 · 22 min
Episode 214 – The Future of Medicine Requires Trust, Technology, and Leadership
The Big Unlock · Dhruv Khullar, M.D., Associate Professor of Medicine and Population Health Sciences, Weill Cornell Medicine In this episode, Dr. Dhruv Khullar, Associate Professor of Medicine and Population Health Sciences at Weill Cornell Medicine, exp
June 24 · 29 min
Episode 213 – Innovation is About Solving Problems, Not Chasing Technology
The Big Unlock · Julie Demaree, VP, Chief Technology and Digital Innovation Officer, St. Mary’s Healthcare In this episode, Julie Demaree, Vice President and Chief Technology and Digital Innovation Officer at St. Mary’s Healthcare, shares a pragmat
June 22 · 22 min
Episode 212 – Value-Based Care is the Optimal Canvas for Generative AI
The Big Unlock · Marshall Glanzer, Chief Technology Officer, Town Square Health In this episode, Marshall Glanzer, Chief Technology Officer of Town Square Health, outlines a bold model for scaling fully capitated risk programs for Medicare recipients. Tr
June 16 · 25 min
Episode 211 – Shifting from Episodic Failures to Proactive Population Health in Rural Care Delivery
The Big Unlock · Ben Long, MD, Director of Hospital Medicine, Magnolia Regional Health Center and Weston Blakeslee, Ph.D., VP of Clinical Intelligence, DrFirst In this episode, Dr. Ben Long, Director of Hospital Medicine at Magnolia Regional Health Cente
June 9 · 25 min
Accelerating Pediatric Digital Health Innovation Through Deep Institutional Collaboration
The Big Unlock · Omkar Kulkarni, VP, Chief Transformation & Innovation Officer, Children’s Hospital Los Angeles (CHLA) In this episode, Omkar Kulkarni, VP, Chief Transformation & Innovation Officer at Children’s Hospital Los Angeles (
June 2 · 25 min
Restoring the Intimate Physician Patient Relationship with Ambient AI
The Big Unlock · Podcast with Dr. Nele Jessel, Chief Medical Officer, athenahealth In this episode, Dr. Nele Jessel, Chief Medical Officer at athenahealth, explores the rapid shift in physician sentiment toward AI and why healthcare may finally be reachi
May 26 · 21 min
Pilot Purgatory to Enterprise Impact and the Unicorn Protocol for AI Success
The Big Unlock · Sally Ann Frank, Global Lead – Health & Life Sciences, Microsoft for Startups In this episode, Sally Ann Frank, Global Lead for Health and Life Sciences at Microsoft for Startups, discusses how AI is moving beyond experimentation tow
May 19 · 20 min
Rural Resilience and Balancing Clinical Care with AI Innovation
The Big Unlock · Andrew Porter, CEO, Wayne General Hospital In this episode, Andrew Porter, CEO of Wayne General Hospital, shares how a community-based health system is navigating the dual pressures of financial sustainability and rural healthcare deli
May 13 · 25 min
Reimagining Healthcare Through AI-Native Orchestration and Digital Platforms
The Big Unlock · Bharat Sutariya, MD, Senior Vice President and Chief Health Officer, Oracle Health In this episode, Dr. Bharat Sutariya, Senior Vice President and Chief Health Officer at Oracle Health, discusses the radical transformation of healthcare
May 5 · 18 min
Building Strategy-Driven Technology in Rural Health Systems
The Big Unlock · Linda Stevenson, Chief Operations & Information Officer, Fisher-Titus Health In this episode, Linda Stevenson, Chief Operations & Information Officer at Fisher-Titus Health, shares how rural health systems are driving innovation
April 30 · 23 min
AI Adoption in Healthcare Must Be Led by Clinicians
The Big Unlock · Dr. Ruchi Garg, Chief Medical Officer, Fairview Park Hospital In this episode, Dr. Ruchi Garg, Chief Medical Officer at Fairview Park Hospital, shares how frontline clinicians are shaping the responsible adoption of AI in real-world care
April 28 · 20 min
AI Should Make Healthcare Feel More Human
The Big Unlock · Ed Lee, MD, MPH, Chief Medical Officer, Nabla In this episode, Dr. Ed Lee, Chief Medical Officer at Nabla, shares how AI is moving beyond hype to reshape real-world care delivery. Drawing on his experience at Kaiser Permanente, he emphas
April 21 · 24 min
AI Will Shape Healthcare Through Access and Affordability
The Big Unlock · Roy Schoenberg, M.D., CEO, Aileen and Founder and Executive Director, Amwell In this episode, Dr. Roy Schoenberg, CEO of Aileen and Founder and Executive Director of Amwell, reflects on the evolution of telehealth and shares a bold vis
April 14 · 27 min
AI Leadership Starts with a Simplified, Integrated Tech Stack
The Big Unlock · Michael Hasselberg, PhD, RN, Chief Transformation and Digital Officer, Nebraska Medicine In this episode, Dr. Michael Hasselberg, Chief Transformation and Digital Officer at Nebraska Medicine, makes a compelling case that sustainable dig
April 7 · 22 min
Healthcare Needs Real Disruption, Not Incremental Change
The Big Unlock · Dr. Stephen K. Klasko, Executive in Residence, General Catalyst & Board Chair, DocGo, Teleflex In this episode, Dr. Stephen K. Klasko, former CEO of Jefferson Health, Executive in Residence at General Catalyst, Board Chair at DocGo,