The Big Unlock

Rohit Mahajan & Ritu M. Uberoy

THE BIG UNLOCK PODCAST is a Healthcare Digital Transformation Podcast. Stay Updated on Healthcare’s Digital Transformation Trends. Featuring C-suite Leaders and Insights on Digital Health Innovation. Explore Emerging Healthcare Technologies with Rohit Mahajan and Ritu M. Uberoy.

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28 episodes
weekly
Avg 24 min
English

Episodes 28

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Tuesday · 26 min
Episode 227 – AI-Native Means Rethinking the Workflow, Not Bolting on AI
The Big Unlock · Don Woodlock, President, InterSystems In this episode, Don Woodlock, President of InterSystems, discusses what it takes to make AI work effectively in healthcare. He emphasizes that organizations need to look beyond models and focus equa
September 16 · 23 min
Episode 226 – Healthcare AI Requires Workflow Transformation, Not Just Technology
The Big Unlock · Roberta L. Schwartz, PhD, EVP, Houston Methodist Hospital and CIO, Houston Methodist In this episode, Roberta Schwartz, Executive Vice President at Houston Methodist Hospital and Chief Innovation Officer at Houston Methodist, explores ho
September 8 · 24 min
Episode 225 – Moving Healthcare AI from Conversation to Execution
The Big Unlock · Shailu Verma, Chief Executive Officer, Co-founder, Mila Health In this episode, Shailu Verma, CEO and Co-founder of Mila Health, explores how healthcare AI is moving beyond patient engagement and conversational tools toward AI agents tha
September 1 · 26 min
Episode 224 – AI Can Augment Clinical Judgment Without Replacing It
The Big Unlock · Dr. Ami Bhatt, Chief Medical Officer, WHOOP In this episode, Dr. Ami Bhatt, Chief Medical Officer at WHOOP and former Chair of the FDA Digital Health Advisory Committee, explores how healthcare can embrace AI without losing the clinical
August 25 · 31 min
Episode 223 – From Legacy Systems to AI-Native Healthcare in Rural America
The Big Unlock · Michael Archuleta, Chief Information Officer, Mt. San Rafael Hospital and Clinics In this episode, Michael Archuleta, Chief Information Officer at Mount San Rafael Hospital, explores how technology can help rural health systems deliver h
August 20 · 30 min
Episode 222 – AI is Moving Drug Discovery From Prediction to Generation
The Big Unlock · Alex Zhavoronkov, Founder, CEO and CBO, Insilico Medicine In this episode, Alex Zhavoronkov, Founder, CEO and CBO of Insilico Medicine, explores how generative AI is reshaping drug discovery and opening new possibilities in longevity res
August 18 · 26 min
Episode 221 – Making Human Movement Measurable with AI
The Big Unlock · Zaw Thet, CEO and Co-Founder, Exer AI In this episode, Zaw Thet, CEO and Co-founder of Exer AI, explores how AI-powered computer vision can make human movement measurable and transform the delivery of musculoskeletal and movement health.
August 11 · 28 min
Episode 220 – Cloud and AI Are Reshaping Healthcare Transformation
The Big Unlock · Dr. Angela Shippy, Senior Physician Executive and Clinical Innovation Lead, Amazon Web Services (AWS) In this episode, Dr. Angela Shippy, Senior Physician Executive and Clinical Innovation Lead at Amazon Web Services (AWS), shares how cl
August 4 · 22 min
Episode 219 – Health Literacy is Key to Better Patient Outcomes
The Big Unlock · Greg O’Neill, Director, Patient & Family Health Education, ChristianaCare In this episode, Greg O’Neill, Director of Patient & Family Health Education at ChristianaCare, explores why effective communication is one of the mo
July 28 · 23 min
Episode 218 – Using Multimodal Foundations and Ambient AI to Scale Clinical Impact
The Big Unlock · Umesh Rustogi, General Manager, HLS Dragon & Platform, Microsoft In this episode, Umesh Rustogi, General Manager, Healthcare & Life Sciences Dragon & Platform at Microsoft, explains that meaningful AI outcomes depend on combi
July 21 · 25 min
Episode 217 – Building Trust in the Next Generation of Healthcare AI
The Big Unlock · Dr. Haider Warraich, Program Manager, Scalable Solutions, ARPA-H In this episode, Dr. Haider Warraich, Program Manager, Scalable Solutions at Advanced Research Projects Agency for Health (ARPA-H), explains why building trust, not just ad
July 13 · 25 min
Episode 216 – The Future of Healthcare Lies in Connected, Evidence-Based Systems
The Big Unlock · Dr. Anne Snowdon, Scientific Director and CEO, SCAN Health and Chief Scientific Research Officer, HIMSS In this episode, Dr. Anne Snowdon, Scientific Director and CEO at SCAN Health and Chief Scientific Research Officer at HIMSS, explore
July 6 · 24 min
Episode 215 – Bridging Pharma and Startups to Scale Digital Health Innovation
The Big Unlock · Naomi Fried, PhD, Founder and CEO, PharmStars In this episode, Naomi Fried, PhD, Founder and CEO of PharmStars, shares how stronger collaboration between startups and pharmaceutical companies is accelerating healthcare innovation. Drawin
June 29 · 22 min
Episode 214 – The Future of Medicine Requires Trust, Technology, and Leadership
The Big Unlock · Dhruv Khullar, M.D., Associate Professor of Medicine and Population Health Sciences, Weill Cornell Medicine In this episode, Dr. Dhruv Khullar, Associate Professor of Medicine and Population Health Sciences at Weill Cornell Medicine, exp
June 24 · 29 min
Episode 213 – Innovation is About Solving Problems, Not Chasing Technology
The Big Unlock · Julie Demaree, VP, Chief Technology and Digital Innovation Officer, St. Mary’s Healthcare In this episode, Julie Demaree, Vice President and Chief Technology and Digital Innovation Officer at St. Mary’s Healthcare, shares a pragmat
June 22 · 22 min
Episode 212 – Value-Based Care is the Optimal Canvas for Generative AI
The Big Unlock · Marshall Glanzer, Chief Technology Officer, Town Square Health In this episode, Marshall Glanzer, Chief Technology Officer of Town Square Health, outlines a bold model for scaling fully capitated risk programs for Medicare recipients. Tr
June 16 · 25 min
Episode 211 – Shifting from Episodic Failures to Proactive Population Health in Rural Care Delivery
The Big Unlock · Ben Long, MD, Director of Hospital Medicine, Magnolia Regional Health Center and Weston Blakeslee, Ph.D., VP of Clinical Intelligence, DrFirst In this episode, Dr. Ben Long, Director of Hospital Medicine at Magnolia Regional Health Cente
June 9 · 25 min
Accelerating Pediatric Digital Health Innovation Through Deep Institutional Collaboration
The Big Unlock · Omkar Kulkarni, VP, Chief Transformation & Innovation Officer, Children’s Hospital Los Angeles (CHLA) In this episode, Omkar Kulkarni, VP, Chief Transformation & Innovation Officer at Children’s Hospital Los Angeles (
June 2 · 25 min
Restoring the Intimate Physician Patient Relationship with Ambient AI
The Big Unlock · Podcast with Dr. Nele Jessel, Chief Medical Officer, athenahealth In this episode, Dr. Nele Jessel, Chief Medical Officer at athenahealth, explores the rapid shift in physician sentiment toward AI and why healthcare may finally be reachi
May 26 · 21 min
Pilot Purgatory to Enterprise Impact and the Unicorn Protocol for AI Success
The Big Unlock · Sally Ann Frank, Global Lead – Health & Life Sciences, Microsoft for Startups In this episode, Sally Ann Frank, Global Lead for Health and Life Sciences at Microsoft for Startups, discusses how AI is moving beyond experimentation tow

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