
Oxford Biologist: Health is NOT in your Genes | Denis Noble
Oxford physiologist Denis Noble reveals why your genes are not the blueprint for life, why evolution itself works nothing like the selfish gene made us believe, and why the failed promise to cure disease by reading our DNA points to a completely different understanding of health and aging! Denis Noble built the first working mathematical model of the heart in 1960 and is one of the founding figures of systems biology. He is a professor at Oxford with a career spent studying how living systems work, and he now argues that the genome is a database the living cell draws on, not the program running the show. He explains: ◼️Why the Human Genome Project never delivered the cures we were promised ◼️Why your DNA cannot actually predict most disease ◼️The CD analogy: why studying genes tells you nothing about the music of life ◼️His long-running clash with Richard Dawkins and the selfish gene ◼️Why purpose and intelligence run all the way down, from your immune system to a predator hunting its prey Episode Show Notes: https://livelongerworld.com/p/denisnoble TIMESTAMPS: 00:00 The Selfish Gene Is Just Not Correct 00:21 What Are Functional Networks, Really? 02:09 Genes Build the Muscles, But Don't Move Them 09:42 Your Genes Are a CD, Not the CD Player 12:11 Can Your DNA Predict Your Disease? 14:23 If Not Genes, How Do We Find Cures? 18:18 Then Does Gene Therapy Even Work? 21:32 Why Scientists Can't Let the Paradigm Go 24:08 What Darwin and Lamarck Actually Said 31:42 Do Animals Choose? Darwin Thought So 38:07 The Finite Monkeys Problem With Evolution 45:15 Inheritance Without Changing Your DNA 49:31 How Do You Actually Reproduce Denis Noble? 50:49 Is the Selfish Gene Right From Evolution's View? 54:45 Answering Jerry Coyne: Isn't DNA the Recipe? 59:51 Who Wrote the Genetic Code? 1:08:22 The Problem of Form: You Can't Get It From Genes 1:12:01 The Mitochondria Accident That Made Complex Life 1:13:05 Why Big Life Needs a Heart 1:17:54 Why Mars Is a Pipe Dream 1:18:45 Mike Levin and the Alignment of the Body 1:21:29 What Does Denis Disagree With Mike Levin On 1:24:59 The Biggest Taboo: Purpose in Biology 1:27:35 Is Consciousness Just Expensive Energy? 1:28:55 What Your Immune System Knows 1:42:01 How Birds at Altitude Prove the Point 1:44:29 Final Thoughts: Life Is More Interesting Than You Think DENIS NOBLE: Website: https://www.denisnoble.com/ Books: https://www.denisnoble.com/buy/ AASTHA, LIVE LONGER WORLD: Newsletter: https://livelongerworld.com/ X: https://x.com/aasthajs Instagram: https://www.instagram.com/aasthajs/ My health stack: https://www.healthstacked.com/aasthajs Full list of health products I use: https://www.healthstacked.com/aasthajs CAMERON, RICCI FLOW NUTRITION: Newsletter: https://ricciflow.substack.com/ X: https://x.com/ricciflowhealth Instagram: https://www.instagram.com/ricciflownutrition/ PREVIOUS PODCAST WITH DENIS NOBLE & MICHAEL LEVIN on Biology's Functional Networks, NOT Genes, are key for Longevity: https://www.youtube.com/watch?v=0_Ak-1rbbWg&t=3823s