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JAMA+ AI Conversations

JAMA Network

Discover the future of medicine with JAMA+ AI Conversations. This collection of interviews with clinicians, researchers, and AI experts explores how AI is impacting medicine – from clinical practice to training and research. Join us to uncover what lies ahead at the intersection of AI and medicine.

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  • 25 episodes
  • fortnightly
  • Avg 21 min
  • English

Episodes 25

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  • January 29 · 12 min

    Chatting With a Chatbot: The History of the First Clinical Chatbots, Straight From an LLM

    A large language model (LLM) details the history of 2 early chatbots, ELIZA and PARRY, in conversation with JAMA+ AI Editor in Chief Roy Perlis. This podcast was recorded using OpenAI's ChatGPT in voice mode, via web interface, running on GPT-4o. Related Content: What Can 50-Year-Old Chatbots Teach Us About Clinical Applications of AI?

  • January 15 · 21 min

    Seeing Health Through the Eye and AI

    Retinal images are becoming powerful windows into human health. Cecilia Lee, MD, MS, joins JAMA and JAMA+ AI Associate Editor Yulin Hswen to explore how AI-enhanced imaging reveals early disease signals, leverages large datasets, and shifts clinical practice in ophthalmology. Related Content: Insights From the Eye With AI

  • Dec 30, 2025 · 17 min

    Multiple Reasoning Models and the Future of AI Chatbots

    AI chatbots have advanced rapidly, incorporating new reasoning architectures that reshape decision-making and medical education. Jonathan Chen, MD, PhD, and Ethan Goh, MD, MS, of Stanford University join JAMA and JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, to discuss the latest generation of AI models, the importance of evaluating benefits and harms, and sycophancy in AI systems. Related Content: Multiple Reasoning Models and the Future of AI Chatbots AI Chatbots in Clinical Practice Large Language Model Influence on Diagnostic Reasoning

  • Dec 18, 2025 · 19 min

    Discussing the Latest Research in AI and Health

    JAMA+ AI Editor in Chief Roy Perlis and Associate Editor Yulin Hswen discuss some of the most cited AI papers in 2025 across the JAMA Network. A little bit of gen AI, some prediction models, and deep learning from videos as well as an increasing awareness of the challenges of real-world deployment. Related Content: AI and Health—The Year in Review

  • Nov 20, 2025 · 26 min

    Designing AI for Uncertainty: A Conversation With Eric Horvitz

    How can AI systems reason safely in the open world of medicine? JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, talks with Eric Horvitz, MD, PhD, Chief Scientific Officer at Microsoft, about the future of AI in 5 years to 100 years, from neurons to the nebulous, and how we can guide AI to be copilots while maintaining integrity and safety in the clinical arena. Related Content: AI—Days of Future Past

Showing 21–25 of 25 episodes