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Inside the Microbiology QC Laboratory

Pierre Barbez

Welcome to SuperMicrobiologists, the podcast for microbiologists working in Quality Control labs.

It all starts with a simple observation: as microbiologists, we often spend more time talking to our Petri dishes than to microbiologists from other laboratories.

Not necessarily by choice... but most of the time, we simply don't have the time, the budget, or the opportunity.

This podcast was designed to be listened to right in the lab, while you're running your tests and experiments.

The goal is simple: to hear what is happening in other laboratories and build connections between microbiologists around the world.

We'll be talking with microbiologists who will share their work, their laboratories, their contamination investigations, their challenges, and of course their successes... because there are plenty of those too.

In short, on the SuperMicrobiologists podcast, we cultivate bacteria... but we also cultivate ideas.

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  • 3 episodes
  • Avg 1 hr 3 min
  • English

Episodes 3

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  • S1 · E3
    Sunday · 47 min

    Bacterial Endotoxin Testing: What Does Automation Really Change? -Meg Provenzano

    Bacterial endotoxin testing (BET) is full of challenges… and surprises! In this episode, Meghan Provenzano from Veolia shares her hands-on experience with BET, from unexpected contamination and tricky interferences to false negatives and troubleshooting. We also explore automation, its benefits and limitations, and the transition from traditional LAL to recombinant methods. A practical discussion packed with real-life laboratory examples! Bonus: Looking for the right BET solution for your lab? Discover the 3 favorite bacterial endotoxin testing suppliers, selected by the SuperMicrobiologists community! Content : 00:27 Introduction to Endotoxin Testing 03:00 Understanding Endotoxins and Their Impact 06:15 Testing Methods: From Rabbits to LAL 09:09 Challenges in Endotoxin Testing 11:55 Interference in Assays: Causes and Solutions 14:50 Best Practices for Accurate Testing 17:47 Common Mistakes in Endotoxin Testing 20:53 Final Thoughts and Recommendations 24:10 Challenges in Endotoxin Testing 28:53 Innovations in BET Solutions 31:58 Advantages of Microfluidic Technology 33:51 Limitations and Considerations of New Technologies 36:47 Understanding Recombinant Solutions 41:33 Transitioning from LAL to Recombinant Testing

    • Transcript
  • S1 · E2
    July 29 · 1 hr 8 min

    How to choose a Rapid Microbiology Method for CGT and ATMP - Dimitra Sakoula

    In this episode, Dimitra explains how to choose an ARMM - an Alternative and Rapid Microbiology Method - for innovative medicines such as cell and gene therapies and ATMPs. She discusses: The methods she has already used, along with their advantages and limitations. How to build a clear URS before selecting a technology. Why primary validation is so important for shortening the validation process. And don't miss the Selection of the 4 Best Rapid Microbiology Methods and their challengers. Enjoy the podcast!

    • Transcript
  • S1 · E1
    July 13 · 1 hr 13 min

    Understanding Rapid Microbiology Methods - Michael Miller

    In this podcast, Michael Miller covers all the hot topics surrounding Rapid and Alternative Microbiology Methods in the pharmaceutical industry. Of course, we also take a deep dive into the brand-new PDA Technical Report 33, released in July 2026. Among the topics discussed: How do you build a business case and calculate the ROI of an RMM? Should we say RMM, ARMM, or Modern Methods? The Biggest RMM mistakes Why is now the right time to adopt RMMs? What is a Primary Validation? And don't miss the Selection of the 4 Best Rapid Microbiology Methods and their challengers. Enjoy the podcast! Content : 00:27 Introduction to Rapid Microbiology Methods 03:06 Early Experiences in Pharmaceutical Microbiology 05:41 Regulatory Changes and Their Impact 08:36 Technical Report 33 Overview 11:52 Collaboration with Regulatory Agencies 14:45 The Future of Rapid Microbiology Methods 17:41 Understanding Terminology in Microbiology Methods 20:41 Supplier Collaboration and Industry Expectations 37:36 Validation Protocols and Statistical Analysis 42:04 Success Stories in Pharmaceutical Manufacturing 47:46 The Importance of Rapid Methods in ATMPs 51:25 Challenges in User Requirement Specifications 53:43 Trusting Supplier Validation 56:38 The Future of Rapid Micro Methods 01:00:42 Conferences and Resources for Rapid Microbiology 01:10:25 Conclusion and Future Outlook

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