GPnotebook Podcast

GPnotebook

A bite-sized, regular chat for all healthcare professionals working in primary care. Episodes cover clinical tips and hot topics. New episodes published every Thursday or Friday.

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217 episodes
Updated Thursday

Episodes217

Newest first

Thursday · 17 min
Ep 217 – Illness anxiety disorder
In this episode, Dr Roger Henderson discusses illness anxiety disorder (IAD), a condition that presents unique challenges for both patients and healthcare professionals. Formerly known as hypochondriasis, IAD is characterised by a persistent fear of having or developing a serious medical illness despite appropriate evaluation and reassurance. These patients often present in primary care and specialist settings, frequently seeking answers for symptoms that may be minimal or entirely absent. Recognising the condition is important, as repeated investigations alone rarely alleviate distress and can contribute to unnecessary healthcare utilisation. This episode explores the clinical features, risk factors, diagnostic criteria, differential diagnosis and evidence-based management of IAD. It also discusses practical strategies for building therapeutic relationships and supporting these patients in a compassionate and effective manner. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/psychiatry/ep-217-illness-anxiety-disorder. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.
July 23 · 17 min
Ep 216 – Alopecia
In this episode, Dr Roger Henderson provides an overview of alopecia, one of the most common yet often misunderstood conditions encountered in clinical practice. While hair loss is rarely life-threatening, it can have a profound impact on a patient’s psychological wellbeing, self-esteem and quality of life. Alopecia is not a single disease but a clinical sign with numerous underlying causes, ranging from temporary and reversible conditions to forms of permanent scarring hair loss; for GPs, distinguishing between these types is essential for accurate diagnosis, timely intervention and effective management. The episode covers the major categories of alopecia, reviews key clinical features and diagnostic approaches, and explores current treatment strategies. It also considers the important psychosocial effects of hair loss and the role GPs play in supporting affected patients. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/dermatology/ep-216-alopecia. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.
July 16 · 14 min
Ep 215 – Hiccups
Hiccups are a common symptom, with short-lived episodes usually being a source of amusement rather than distress. For these acute episodes, simple nonpharmacologic techniques are often effective. However, persistent hiccups greatly affect quality of life and can be difficult to manage. There is often significant diagnostic dilemma, with potentially serious and even life-threatening underlying causes needing to be considered. In this episode, Dr Kate Chesterman discusses the investigation and management of hiccups. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/general-practice/ep-215-hiccups. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.
July 9 · 14 min
Ep 214 – Pneumococcal disease
In this episode, Dr Roger Henderson explores pneumococcal disease and the major changes coming to the UK pneumococcal vaccination programme in 2026. Although often overshadowed by other infectious diseases, Streptococcus pneumoniae remains a leading cause of preventable morbidity and mortality worldwide, particularly among older adults, young children and immunocompromised patients. This episode discusses the microbiology and clinical manifestations of pneumococcal disease, reviews the immunological principles behind current vaccines and examines why the UK is transitioning towards the use of the 20-valent pneumococcal conjugate vaccine, or PCV20. It also looks at the wider public health implications of these policy changes and considers how evolving serotype epidemiology continues to shape vaccination strategy in modern clinical practice. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/infectious-disease/ep-214-pneumococcal-disease. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.
July 2 · 15 min
Ep 213 – Polymyalgia rheumatica
In this episode, Dr Roger Henderson explores polymyalgia rheumatica (PMR), a common but often underestimated inflammatory condition affecting older adults. Although many clinicians recognise the classic presentation of shoulder and hip girdle stiffness, PMR is far more than a simple musculoskeletal complaint. Its overlap with giant cell arteritis (GCA), the challenges of long-term steroid management and the importance of recognising red-flag symptoms make it a condition that requires careful clinical judgement. Join us as we walk through the typical patient presentation, discuss the underlying inflammatory mechanisms, review current diagnostic approaches and explore practical management strategies, including relapse prevention and steroid-sparing therapies. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/rheumatology/ep-213-polymyalgia-rheumatica. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.
June 25 · 18 min
Ep 212 – Herpes zoster
In this episode, Dr Roger Henderson looks at a condition every GP recognises, but not always in its earliest or most subtle form: shingles. Also known as herpes zoster, it is far more than just a painful rash – it’s the reactivation of a neurotropic virus that may have been lying dormant for decades within the nervous system. Here, we explore how and why that reactivation occurs and what clinical clues can help you identify the condition even before the rash appears. We walk through the typical and atypical presentations, highlight key complications and discuss why early treatment can make a meaningful difference to patient outcomes. We also consider high-risk groups, including older adults and immunocompromised patients, where the disease burden is greatest. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/infectious-disease/ep-212-herpes-zoster. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.
June 18 · 14 min
Ep 211 – Mumps
In this episode, Dr Roger Henderson looks at a condition that many clinicians associate with pre-vaccine paediatrics, yet which still occurs: mumps. While its incidence has dramatically declined since the introduction of the measles, mumps and rubella vaccine, it has not disappeared. Here, we walk through why mumps still matters clinically, from its systemic viral nature and characteristic parotitis, to less obvious presentations like orchitis and aseptic meningitis. We also explore why vaccinated populations can still be affected, how diagnosis is confirmed in practice and what clinicians need to remember about public health reporting. Although usually self-limiting, mumps remains a notifiable disease with important implications for outbreak control and patient counselling in everyday clinical work. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/infectious-disease/ep-211-mumps. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.
June 11 · 17 min
Ep 210 – Bacterial meningitis and meningococcal disease
In this episode, Dr Hannah Rosa discusses bacterial meningitis and meningococcal disease, with a focus on the NICE guideline that was published in 2024. She reviews how to recognise bacterial meningitis and meningococcal disease and answers the key question: when to give antibiotics outside of hospital? At the end of this episode, there is a chance to put the learning into a clinical context with some clinical scenarios. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/infectious-disease/ep-210-bacterial-meningitis-and-meningococcal-disease. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.
June 4 · 16 min
Ep 209 – Anabolic steroid misuse
In this episode, Dr Roger Henderson explores the growing clinical challenge of anabolic–androgenic steroid (AAS) misuse, a condition increasingly seen in everyday practice. Here, we examine how AAS use has shifted toward appearance-driven motivations, the role of muscle dysmorphia and the influence of gym culture and online communities. This episode highlights key pathophysiological effects, including hypogonadism, cardiovascular risk and neuropsychiatric complications. It also reviews how AAS misuse presents in real-world clinical settings, often through indirect signs rather than disclosure. Finally, it covers practical approaches to recognition, withdrawal management and long-term care, equipping GPs to better identify and support patients affected by this evolving, multi-system disorder. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/general-information/ep-209-anabolic-steroid-misuse. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.
May 28 · 19 min
Ep 208 – Myasthenia gravis
In this episode, Dr Roger Henderson explores the pathophysiology, clinical features and management of myasthenia gravis, an autoimmune disorder affecting the neuromuscular junction. It highlights how antibodies, most commonly against acetylcholine receptors, impair neuromuscular transmission, leading to fatigable weakness that worsens with activity and improves with rest. The discussion emphasises key clinical presentations, including ocular, bulbar and proximal limb weakness, alongside the risk of life-threatening myasthenic crisis. Diagnostic approaches are reviewed, focusing on antibody testing and electrophysiological studies. Management strategies include symptomatic treatment with acetylcholinesterase inhibitors, immunosuppression and thymectomy in selected patients. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/neurology/ep-208-myasthenia-gravis. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.
May 21 · 19 min
Ep 207 – Transient ischaemic attack
In this episode, Dr Roger Henderson looks at one of the most time-sensitive diagnoses in general practice: the transient ischaemic attack, or TIA. Often underestimated because symptoms resolve quickly, a TIA is in fact a powerful warning sign of an impending ischaemic stroke. For GPs, recognising and responding to this brief neurological event can make the difference between prevention and long-term disability. Here we break down the modern tissue-based definition of TIA, highlighting how it differs from older time-based concepts and why that matters in our clinical practice. We also explore the importance of sudden focal symptoms and discuss why the first 48 hours carry the greatest risk. We also look at key causes and outline practical approaches to urgent evaluation, risk stratification and management. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/neurology/ep-207-transient-ischaemic-attack. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.
May 14 · 15 min
Ep 206 – Hypertensive disorders of pregnancy
In this episode, Dr Roger Henderson explores hypertensive disorders of pregnancy – one of the most important and potentially life-threatening conditions encountered in obstetric care. Affecting up to one in 10 pregnancies, these disorders range from mild hypertension to severe complications such as preeclampsia, eclampsia and HELLP (haemolysis, elevated liver enzymes and low platelets) syndrome. Despite advances in prenatal monitoring and management, they remain a leading cause of maternal and foetal morbidity worldwide. Here, we look at the underlying mechanisms, risk factors, clinical features and current management strategies, with a focus on practical insights to support clinical decision-making and improve outcomes for both mother and baby. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/obstetrics/ep-206-hypertensive-disorders-of-pregnancy. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.
May 7 · 24 min
Ep 205 – Metabolic dysfunction-associated steatotic liver disease and hepatitis
Liver disease is often overlooked in primary care, yet it is one of the fastest-growing causes of morbidity and mortality in the UK. Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD), now affects around one-third of the UK population, with prevalence rising and all-cause mortality worsening over time. In this second episode of a series on hepatology and hepatitis, Dr James Waldron is joined by Dr Rik Fijten (GP Partner, Hepatitis C GP Champion for Bexley and GP Clinical Fellow in Gastroenterology) to explore why MASLD matters to GPs, why it is so common and why primary care is central to identifying disease early and preventing progression. They discuss why clinicians need to raise this often “silent” disease proactively and how it should be considered alongside diabetes, hypertension and weight management. The conversation covers how to approach abnormal liver function tests, how to assess fibrosis risk using simple non-invasive tools and how MASLD fits into the wider cardio–renal–metabolic model of long-term condition care. The episode also looks ahead to emerging treatments and what the future may hold for patients. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/infectious-disease/ep-205-metabolic-dysfunction-associated-steatotic-liver-disease-and-hepatitis. Disclaimer This content is for medical education purposes only and does not constitute clinical advice. While specific drugs and dosages may be discussed, clinicians should always refer to local protocols and official prescribing information before administering medication. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.
April 30 · 26 min
Ep 204 – Red legs
Red legs are frequently seen in primary care but are often misdiagnosed. With a need for antimicrobial stewardship, it is important to identify the cause, rather than automatically rely on antibiotic prescription. Importantly, all that is red is not cellulitis; venous or varicose eczema is a common cause of swollen and red legs and requires a different management approach. In this episode, Dr James Waldron is joined by Dr Mark Graham (GP from Nottingham with experience in dermatology) to explore how to invest time initially to achieve the right diagnosis. The discussion considers differential diagnoses, clinical examination and management. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/cardiovascular-medicine/ep-204-red-legs. Disclaimer This content is for medical education purposes only and does not constitute clinical advice. While specific drugs and dosages may be discussed, clinicians should always refer to local protocols and official prescribing information before administering medication. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.
April 23 · 20 min
Ep 203 – Oral mucosal cancer
In this episode, Dr Roger Henderson explores an important and often overlooked area of head and neck oncology: oral mucosal cancer. As GPs, we frequently encounter oral lesions in primary care, and they are also often seen in dental practice, emergency settings and specialist clinics; however, distinguishing benign conditions from early malignancy can be challenging. Here, we break down the essential anatomy of the oral cavity, clarify how it differs from the oropharynx and examine the major risk factors driving disease development, including tobacco, alcohol, human papillomavirus (HPV) and immunosuppression. We also discuss clinical presentation, red-flag features, diagnostic pathways, staging principles and current management strategies. Most importantly, we focus on the role GPs play in early detection, timely referral and multidisciplinary care. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/ear-nose-and-throat/ep-203-oral-mucosal-cancer. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.
April 16 · 18 min
Ep 202 – Labyrinthitis
In this episode, Dr Roger Henderson explores labyrinthitis from a GP’s perspective, moving beyond the textbook definition to focus on practical diagnosis, pathophysiology and management. Although often grouped broadly under causes of acute vertigo, true labyrinthitis is a distinct inflammatory condition of the inner ear that combines vestibular and auditory dysfunction. Its presentation can closely resemble more serious neurological pathology, including posterior circulation stroke, making accurate assessment essential in both primary and acute care settings. This episode examines the underlying causes, key clinical features, important differentials and evidence-based treatment strategies. It aims to refine our diagnostic reasoning, avoid common pitfalls and strengthen confidence when evaluating patients presenting with acute vertigo, hearing loss and associated neuro-otological symptoms in everyday general practice. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/ear-nose-and-throat/ep-202-labyrinthitis. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.
April 9 · 10 min
Ep 201 – Pityriasis rosea
Pityriasis rosea is a common and self-limiting condition, but it can cause significant anxiety and distress for patients. In this episode, Dr Kate Chesterman discusses the expected course and clinical findings that are associated with this condition, as well as exploring possible differentials, treatment options, potential complications and referral criteria. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/dermatology/ep-201-pityriasis-rosea. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.
April 2 · 24 min
Ep 200 – Hepatitis C
Hepatitis C was once considered a chronic, life-limiting condition with difficult treatments and significant stigma. Today, it is one of the great success stories of modern medicine: curable in the vast majority of patients with short courses of well-tolerated oral therapy. Yet, thousands of people in the UK remain undiagnosed. In this first episode of a series on hepatology and hepatitis, Dr James Waldron is joined by Dr Rik Fijten (GP Partner, Hepatitis C GP Champion for Bexley and GP Clinical Fellow in Gastroenterology) to explore why hepatitis C matters to primary care now more than ever. Together, they discuss who should be tested, how to interpret results, what happens after diagnosis and the central role GPs play in the NHS Hepatitis C Elimination Programme. This practical, confidence-building conversation focuses on normalising testing, reducing stigma and being curious, helping primary-care clinicians identify patients who could benefit from life-changing treatment. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/infectious-disease/ep-200-hepatitis-c. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.
March 26 · 16 min
Ep 199 – Gastric cancer
Gastric cancer is often described as a disease in decline, yet it remains one of the deadliest malignancies worldwide. For many GPs, it is a diagnosis that still arrives late, cloaked in vague symptoms and missed opportunities for early intervention. In this episode, Dr Roger Henderson takes a deep, clinically focused look at gastric cancer, from its evolving epidemiology and underlying biology to modern approaches in diagnosis, staging and treatment. He also explores why outcomes differ so dramatically across regions, how molecular insights are reshaping its therapy and what this disease continues to teach us about prevention and early detection. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/gastroenterology/ep-199-gastric-cancer. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.
March 19 · 15 min
Ep 198 – Basal cell cancer
Basal cell carcinoma (BCC) is a diagnosis most GPs encounter regularly, yet its familiarity often disguises its true impact. As the most common cancer in humans, BCC shapes clinical workload, healthcare costs and patient quality of life far more than its low mortality rate suggests. Although it is frequently described as slow growing and low risk, delayed recognition or inadequate treatment can lead to significant local destruction, functional impairment and disfigurement. In this episode, Dr Roger Henderson takes a closer look at BCC beyond the surface, exploring its clinical variability, underlying biology and evolving management strategies. Access episode show notes containing key references and take-home points at: https://gpnotebook.com/en-GB/podcasts/oncology/ep-198-basal-cell-cancer. Did you know? With GPnotebook Pro, you can earn CPD credits by tracking the podcast episodes you listen to. Learn more.