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Dr. John Campbell

Campbellteaching

Hello Everyone, My name is John Campbell and I am a retired Nurse Teacher and former clinical nurse based in England. I also do some teaching in Asia and Africa when time permits. These videos are to help students to learn the background to all forms of health care. My PhD focused on the development of open learning resources for nurses nationally and internationally. LinkedIn profile, https://www.linkedin.com/in/dr-john-campbell-5256223b/ Twitter, https://twitter.com/Johnincarlisle Disclaimer; These media including videos, book, e book, articles, podcasts are not peer-reviewed. They should never replace individual clinical judgement from your own health care provider. No media-based material on this channel is suitable for using as professional medical advice. All comments are also for educational purposed only and must never replace advice from your own health care provider

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October 24 · 22 min
Excess deaths, scarce data
Download free high-res PDFs of the posters, download free copies of my two text books. https://drjohncampbell.co.uk/ Australia, Key statistics https://www.abs.gov.au/statistics/health/causes-death/provisional-mortality-statistics/latest-release In 2022, there were 111,008 deaths that occurred by 31 July, and were registered by 30 September, which is 16,375 (17.3%) more than the historical average. In July there were 17,936 deaths, 2,503 (16.2%) above the historical average. There were 300 (22.5%) fewer deaths due to COVID-19 in August than July. https://www.bhf.org.uk/what-we-do/news-from-the-bhf/news-archive/2022/november/extreme-heart-care-disruption-linked-to-excess-deaths-involving-heart-disease Since the pandemic began Over 30,000 excess deaths involving heart disease (average over 230 additional deaths a week) Heart disease is among the most prominent diseases involved in the high numbers of excess deaths since the start of the pandemic. While Covid-19 infection was likely a significant factor Covid infections no longer a driving force https://www.cancer.gov/news-events/press-releases/2021/covid-19-pandemic-disparities-excess-deaths Meredith S. Shiels, Infections and Immunoepidemiology, NCI Division of Cancer Epidemiology and Genetics Focusing on COVID-19 deaths alone without examining total excess deaths —that is, deaths due to non-COVID-19 causes as well as to COVID-19 —may underestimate the true impact of the pandemic https://www.cdc.gov/cancer/dcpc/research/update-on-cancer-deaths/index.htm https://www.cancerresearchuk.org https://news.cancerresearchuk.org/2020/07/21/why-its-difficult-to-estimate-the-number-of-extra-cancer-deaths-caused-by-service-disruption-during-covid-19/ July, 2022 3,600 to 60,000 excess cancer deaths so far https://www.cancerresearchuk.org/about-cancer/cancer-symptoms Excess mortality in England and English regions: December 2022 update https://www.telegraph.co.uk/news/2022/11/20/true-impact-covid-cancer-patients-revealed-excess-deaths-soar https://www.gov.uk/government/organisations/office-for-health-improvement-and-disparities https://app.powerbi.com/view?r=eyJrIjoiYmUwNmFhMjYtNGZhYS00NDk2LWFlMTAtOTg0OGNhNmFiNGM0IiwidCI6ImVlNGUxNDk5LTRhMzUtNGIyZS1hZDQ3LTVmM2NmOWRlODY2NiIsImMiOjh9 25 to 49 years Based on 2015 to 2019 data Learn more about your ad choices. Visit megaphone.fm/adchoices
October 24 · 7 min
Most common symptoms and immunity
Runny nose, 76%. Headache, 75% Sneezing, 66% Sore throat, 52% Loss of smell, 52% Uploaded 07-10-21 https://covid.joinzoe.com/blog https://www.youtube.com/watch?v=xoGqyFUoUSw Most common symptoms in vaccinated and children Runny nose, 76% Headache, 75% Sneezing, 66% Sore throat, 52% Loss of smell, 52% (Fever nor chronic cough in the top symptoms) Out of date government advice misses 40% of infections Natural immunity, levels of protection against reinfection Natural infection alone in past year, 65% 2 doses of AZ in past 6 months, 71% 2 doses of Pfizer in past 6 months, 83% Infection (past year) followed by 2 doses of AZ, 90% Infection (past year) followed by 2 doses of Pfizer, 94% Contradicts Israeli data Protection of previous SARS-CoV-2 infection is similar to that of BNT162b2 vaccine protection: A three-month nationwide experience from Israel https://www.medrxiv.org/content/10.1101/2021.04.20.21255670v1.full.pdf Protection from prior SARS-CoV-2 infection, 94·8% Hospitalization 94·1% Severe illness 96·4% Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
October 24 · 24 min
Depression, high levels
Free download John’s textbooks in high res pdf. https://drjohncampbell.co.uk Uploaded 22-11-23 Check out Campbell's Physiology Notes Dr John Campbell Sold by author on eBay! https://www.ebay.co.uk/itm/155780745424?mkcid=16&mkevt=1&mkrid=711-127632-2357-0&ssspo=K6raxMZrQnm&sssrc=4429486&ssuid=K6raxMZrQnm&var=&widget_ver=artemis&media=EMAIL Depression https://patient.info/doctor/patient-health-questionnaire-phq-9 Patient Health Questionnaire (PHQ-9) (Scores each of the nine DSM-IV criteria) Over the last two weeks, how often have you been bothered by any of the following problems? Little interest or pleasure in doing things? Feeling down, depressed, or hopeless? Trouble falling or staying asleep, or sleeping too much? Feeling tired or having little energy? Poor appetite or overeating? Feeling bad about yourself - or that you are a failure or have let yourself or your family down? Trouble concentrating on things, such as reading the newspaper or watching television? Moving or speaking so slowly that other people could have noticed? (Or the opposite - being so fidgety or restless that you have been moving around a lot more than usual)? Thoughts that you would be better off dead, or of hurting yourself in some way? Depression Severity 0-4 none 5-9 mild 10-14 moderate 15-19 moderately severe 20-27 severe All features may be self-reported (subjective account) or observed by others In assessing for the presence of major depression Sensitivity of 88% Picks up 88% of cases, misses (false negative) 12 % of cases Specificity of 88% Correctly diagnoses 88% of the time, gives a false positive 12% of the time https://patient.info/mental-health/depression-leaflet/suicidal-thoughts Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
October 24 · 1 hr 10 min
Iodine, a global deficiency
Iodine, Over a third of the global population is exposed to iodine deficiency, especially in the mountains. Uploaded 16-03-25 Most common global preventable cause of mental impairment https://www.westonaprice.org/health-topics/modern-diseases/the-great-iodine-debate/#gsc.tab=0 https://www.lewrockwell.com/2006/08/donald-w-miller-jr-md/you-cant-live-without-it/ https://www.youtube.com/watch?v=Jkpf2j-qNJk Iodine deficiency https://www.who.int/data/nutrition/nlis/info/iodine-deficiency Serious iodine deficiency during pregnancy can result in stillbirth, spontaneous abortion and congenital abnormalities such as cretinism Role of Iodine in Metabolism https://pubmed.ncbi.nlm.nih.gov/28103777/ Urinary Iodine Concentration https://www.kcl.ac.uk/open-global/biomarkers/mineral/iodine/urinary-iodine-concentration In healthy, iodine-replete adults more than 90% of dietary iodine is absorbed from the small intestine and more than 90% is excreted within 24-48 hours Functions Control of metabolic rate, energy levels, weight management, brain function, cardiovascular health, foetal and child development, reduced still births, infection protection in children, breast, ovary, uterus protection, prostate. Many organs can also actively accumulate iodine: salivary glands, stomach, lactating mammary gland, ovary, prostate, pancreas. Recommended dietary intake,150 μg/day The correlation between iodine and metabolism: a review https://pmc.ncbi.nlm.nih.gov/articles/PMC10985161/ Changes in Dietary Iodine Explains Increasing Incidence of Breast Cancer with Distant Involvement in Young Women https://pmc.ncbi.nlm.nih.gov/articles/PMC5327366/ Fibrocystic breast disease Iodine deficiency is associated with fibrocystic breast disease Fibrocystic breast disease can be effectively treated with iodine Fibrocystic breast disease affects at least 50% of women of child-bearing age, and is associated with an increased risk of developing breast cancer. Breast cancer Increasing breast cancer in younger women since mid-1970s Often presenting late Iodine deficiency has been proposed to play a causative role in the development of breast cancer Dietary iodine has also been previously proposed to play a protective role in breast cancer Japanese women, have exceptionally low incidence of breast cancer Emigration of Japanese women, adopting a western diet, associated with higher breast cancer rates. Iodine is taken up by the sodium/iodide symporter in the breast This is important in promoting the development of normal versus neoplastic breast tissue development Reduce breast cancer Vit D and K2, phytonutrients, cruciferous veg, cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, omega 3 Mechanism of action of iodine's anticancer effect Antioxidant, iodide has been found to be highly efficient in scavenging reactive oxygen species Iodine also has well-known anti-inflammatory and immunomodulatory effects Iodine promotes differential apoptosis Iodine promotes of P53 tumour suppressor gene activity Iodine plays a role in the development and maintenance of healthy breast tissue Women with goitre have three times more breast cancer Iodine deficiency results in “hyperresponsiveness” to oestrogen, resulting in increased cell proliferation, abnormal changes within nuclei, Iodine is necessary for breast remodelling during lactation, and pregnancy Young women and pregnant women, have lower urinary iodine levels than men of similar age. Women of childbearing age exhibited the lowest urinary iodine levels of any age group. Atypia is seen more in iodine deficiency in human and animal models Temporal Changes in Body Iodine There has been a drop in urinary iodine in young women as well as in the general population, since the 1970s Nutrition Examination Surveys, A significant decrease in urinary iodine levels in the Learn more about your ad choices. Visit megaphone.fm/adchoices
October 24 · 48 min
Pandemics and ivermectin safety
US deaths more than 1918 pandemic Uploaded 23-09-21 Link to Wefwafwa’s channel https://www.youtube.com/channel/UCzsLklGgOttU3Se-WGLp7ow Link to todays featured video https://www.youtube.com/watch?v=XCKFBJRJcFA To donate to Wefwafwa’s work patreon:https://www.patreon.com/awmedicalvideos https://www.cdc.gov/flu/pandemic-resources/1918-pandemic-h1n1.html H1N1 virus with genes of avian origin United States, first identified in military in spring 1918 One-third of the world’s population became infected Global deaths, at least 50 million US deaths, 675,000 (CDC, 2021, 666,440) (JH, 2021, 681,199) https://coronavirus.jhu.edu/map.html (population, x 3 today) Pandemic subsides, but (H1N1) continues to circulate seasonally for 38 years https://www.cdc.gov/flu/pandemic-resources/1918-commemoration/milestone-infographic.htm Mortality in 1918 / 1919 High in people younger than 5 years old 20-40 years old, and 65 years and older No vaccine, no antibiotics UK in 1918 https://www.historic-uk.com/HistoryUK/HistoryofBritain/The-Spanish-Flu-pandemic-of-1918/ Deaths, 228,000 (2021, 135,621 to 158,664) Global infection fatality rate, 10% to 20% Mr Biden Extra 500 million Pfizer doses for poorer countries The Food and Drug Administration https://www.washingtonpost.com/health/2021/09/22/pfizer-booster-shot-fda-authorizes/ Authorized a Pfizer booster, 65 and older People 18 through 64, at high risk of severe illness frequent institutional or occupational exposure Six months Issuing emergency clearance FDA commissioner Janet Woodcock health care workers, teachers and day care staff, grocery workers, homeless shelters or prisons Centers for Disease Control and Prevention still must make precise recommendations Key goal of boosters, prevention of serious disease, not prevention of mild infection ? Pfizer booster for people who have been vaccinated with the Moderna or Johnson and Johnson Fewer side effects after third dose of mRNA vaccines compared with the second dose https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2021-09-22/07-COVID-Talbot-508.pdf COVID-19 Vaccine Safety Technical (VaST) Work Group Assessment of 3rd dose safety data H. Keipp Talbot, MD MPH (VaST Chair) Robert H. Hopkins, Jr., MD (NVAC Chair) Israel 3rd doses ,~2.8 M ≥12 years Most to persons ≥60 years Rates of reported systemic, local, neurologic, allergic, and other reactions were substantially lower after dose 3 than after dose 1 or 2 1,328 non serious 19 serious adverse events, (7 possibly associated with vaccination) https://www.who-umc.org/vigibase/vigibase/ http://www.vigiaccess.org Correction https://www.hindustantimes.com/cities/lucknow-news/yogi-adityanath-launches-covid-19-medical-kits-for-covid-19-symptomatic-children-101623747649057.html State government, 50 lakh medical kits through village surveillance committees Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
October 24 · 23 min
Cancers in the young
Tucker Carlson and Dr. Patrick Soon-Shiong https://www.youtube.com/watch?v=mgZaT-OriO8&t=668s Uploaded 30-03-25 Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
October 24 · 1 hr 7 min
Insulin resistance with Dr. Dhand
The current pandemic Uploaded 12-10-25 Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
October 24 · 17 min
Lockdowns, weak evidence
Evidence for non-pharmaceutical interventions such as mass lockdowns was weak. (Not that you could have guessed that easily at the time from government messaging). Uploaded 02-10-23 Research and analysis COVID-19: non-pharmaceutical interventions to reduce transmission https://www.gov.uk/government/publications/covid-19-non-pharmaceutical-interventions-to-reduce-transmission 28 September 2023 Identify and categorise primary studies that reported on the effectiveness of non-pharmaceutical interventions (NPIs), implemented in community settings to reduce the transmission of coronavirus (COVID-19) in the UK. Physical distancing Surface cleaning Face coverings Hand and respiratory hygiene Ventilation Measures to identify and isolate those who are infectious or may become infectious, such as testing and isolation (also known as quarantine) Measures to reduce the number of contacts, including lockdown, settings closures and limitation of social contacts (such as the ‘rule of 6’) Shielding of the most clinically vulnerable Travel and border restrictions Review includes 151 studies (search date: 1 March 2023) Evidence gap map for NPIs https://research.ukhsa.gov.uk/evidence-gap-map-npi-and-covid-19/ Only 19 of the 151 studies reported on effectiveness of measures to reduce infection risk at individual level, of which 14 reported on face coverings. This suggests that there is an evidence gap for other measures within this category, such as hand and respiratory hygiene, ventilation and cleaning (studies that reported on packages of NPIs were excluded). Two-thirds of the evidence identified was based on modelling studies (100 out of 151 studies). There was a lack of experimental studies (2 out of 151 studies) Individual-level observational studies (22 out of 151 studies). On measures aimed to reduce infection risk at individual level The evidence available for this category is therefore likely to be weak, both in terms of study design and potential bias. Studies reporting on travel and border restrictions a weak evidence base in terms of study design. Apart from test and release strategies for which 2 randomised controlled trials (RCTs) were identified, the body of evidence available on effectiveness of NPIs in the UK provides weak evidence in terms of study design, as it is mainly based on modelling studies, ecological studies, (relationship between outcome and exposure at a population level) mixed-methods studies and qualitative studies. For future pandemic preparedness A need to strengthen evaluation of interventions, and build this into the design and implementation of public health interventions, and government policies from the start of any future pandemic, or other public health emergency. The next steps are to critically appraise and synthesise the evidence identified on the effectiveness of individual NPIs, implemented in community settings to reduce the transmission of COVID-19 in the UK. There is also a need to review and assess the evidence on the economic impact of NPIs, as well as their wider impact, including on mental health and health inequalities. For future reports More on harm / benefit analysis Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
October 24 · 12 min
Mushrooms, herbs
Discussion for educational and discussion purposes only. Do not stop or start any herbal or medical treatment based on content on this channel. Dr. William Makis MD. Radiologist, Oncologist, Cancer Researcher, Author of 100+ publications. Top Substack Author. Uploaded 29-04-25 Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
October 24 · 32 min
Vaccines and sperm counts
Sperm Parameters Before and After COVID-19 mRNA Vaccination Uploaded 09-08-21 https://jamanetwork.com/journals/jama/fullarticle/2781360 https://www.dw.com/en/covid-vaccine-the-unfounded-tale-of-infertility/a-58753946 Reproductive toxicity was not evaluated in the clinical trials SARS-CoV-2 has been associated with decreases in sperm parameters We assessed sperm parameters before and after mRNA vaccine administration Volunteers aged 18 to 50 years, n = 45 Scheduled for mRNA COVID-19 vaccination Participants provided a semen sample after 2 to 7 days of abstinence prior to receiving the first vaccine dose Then median 75 days after the second Semen analyses semen volume, sperm concentration, sperm motility, and total motile sperm count Results December 17, 2020 to January 12, 2021 Of the 45 men 21 (46.7%) received BNT162b2 (Pfizer) 24 (53.3%) mRNA-1273 (Moderna) Baseline Median sperm concentration, 26 million per ml Total motile sperm count, 36 million After second vaccine dose Median sperm concentration, 39 million per ml Total motile sperm count, 44 million Semen volume and sperm motility also significantly increased Eight of the 45 men were oligospermic before the vaccine Of these 8, 7 men had increased sperm concentration to normozoospermic Men with oligospermia did not experience further decline No man became azoospermic after the vaccine Discussion No significant decreases in any sperm parameter among small cohort of healthy men Vaccines contain mRNA and not the live virus, unlikely that the vaccine would affect sperm parameters Reasons for the increases Magnitude of change is within normal individual variation May be influenced by regression to the mean Increased abstinence time before the second sample. Study’s time frame encompasses the full life cycle of sperm https://msdh.ms.gov/msdhsite/_static/14,21994,420,873.html Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
October 24 · 14 min
Madness of Crowds
The Madness of Crowds Uploaded 18-08-25 Extraordinary Popular Delusions and the Madness of Crowds (Charles Mackay, 1841). Economic bubbles The Love of the Marvellous and the Disbelief of the True Peculiar Follies The Crusades The Witch Mania The Slow Poisoners Philosophical Delusions The Alchemysts Fortune Telling The Magnetisers (Frans Mesmer) Remedy to groupthink Uphold the right of dissenters to be heard. Medical journals, actively encourage the discussion of contrarian ideas Stop punishment for dissenters Address financial and other conflicts of interest. Indulge those occupied with “taboo science,” while still adhering to time-tested scientific principles and methods. Be aware of manipulating psychopaths and sociopaths (JC) Something is rotten in the Academy. We need to improve. Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
October 24 · 6 min
DW Omicron talk
Thanks to Marianna and DW. This would have been a better answer to the question I messed up: Two-dose Pfizer-BioNTech vaccination provides some protection against symptomatic infection with omicron, but significant protection against hospitalisation (South Africa data) 33% protection against infection with omicron, relative to the unvaccinated (down from 80% protection against infection with delta) 70% protection against hospital admission in omicron infection, relative to the unvaccinated (down from 93% protection with delta) Learn more about your ad choices. Visit megaphone.fm/adchoices
October 24 · 29 min
ONS sample group discussion
With, Professor Norman Fenton Uploaded 24-10-22 Links for Professor Fenton, www.normanfenton.com www.youtube.com/@normanfenton81 https://twitter.com/profnfenton Professor Fenton is a mathematician, experienced in electrical engineering and computer science. Highly published and cited academic. Professor of Risk Information Management, Queen Mary London University Specialist in risk management for critical systems. Expert in quantitative risk assessment and predicting the probabilities of unknown events Implications of the Office for National Statistics estimates of Covid-19 vaccine take up in England on the representativeness of its sample population https://www.researchgate.net/publication/364310694_Implications_of_the_Office_for_National_Statistics_estimates_of_Covid-19_vaccine_take_up_in_England_on_the_representativeness_of_its_sample_population?channel=doi&linkId=63459d419cb4fe44f31d90fd&showFulltext=true Is it important to collect quantitively data to learn about a population group? Why do we need a representative sample of a population to collect valid data for the population as a whole? Can you give an example of how a representative sample of a population should be selected? Which sample is used by the ONS to generate their estimates of covid vaccine take up? Is this then a skewed sample? Given that to be included an individual had to have been in the 2011 census and must currently be registered with a GP, how many people are missed out? Of these 8 million people that are missed out from the ONS data, what proportion of these are unvaccinated? Are there any other estimates of the proportion of the population vaccinated for comparative purposes? Does this mean that the sample is not as representative as would be ideal? If the sample is not representative, how does this effect the validity of their data and hence their conclusions? Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
October 24 · 11 min
Deep fakes
Free downloads of my books, https://drjohncampbell.co.uk/ Uploaded 27-02-25 Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
October 24 · 35 min
Canadian Citizens Inquiry
Free report download, https://nationalcitizensinquiry.ca/ Uploaded 15-12-23 Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
October 24 · 1 hr 17 min
Drinking alcohol with Professor Nutt
Professor David Nutt, doctor, psychiatrist, neuropsychopharmacologist, addiction specialist, medical author and researcher. Leading expert on brain chemistry, the effects of alcohol, and the GABA system. Uploaded 13-05-25 Link for Sentia drinks, https://sentiaspirits.com/ David founded SENTIA Spirits to achieve his vision of bringing safer, better choices to adult social drinkers. Link for Drink? UK link, https://www.amazon.co.uk/Drink-Science-Alcohol-Your-Health/dp/B07YX52JLR/ref=sr_1_1?crid=2CICWKTQ2JV3G&dib=eyJ2IjoiMSJ9.aJAoDtBh4cjOSqJe7adChK_tZ8CwQp9YPQgbUer7xKcLmQkqz0biMtFM8Y3SUkzDruAr8hJg8aYyAswq90VrTNa58iL58pFzQJncYJqifnXS3KB0vvalvEqbygogaLqs.G0fMPUA2osO5moD_aY8Vzk9joOSu5dyDJl-Vhk9EdYc&dib_tag=se&keywords=drink+david+nutt&qid=1747172137&sprefix=drink+david+nutt%2Caps%2C91&sr=8-1 US link, https://www.amazon.com/Drink-New-Science-Alcohol-Health/dp/030692384X/ref=sr_1_1?crid=3JE2731TAQ8JO&dib=eyJ2IjoiMSJ9.mwR5QFRJgtmJUODgz0GYy90h23yRviakZe71yl9_qLDGjHj071QN20LucGBJIEps.3Y7Z7ETTPt0FcJL_3WHhXDz5YJUe9HAp3qA3pzkdYoM&dib_tag=se&keywords=drink+david+nutt&qid=1747172435&sprefix=drink+david+nutt%2Caps%2C176&sr=8-1 Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
October 24 · 7 min
Monkeypox in 5 minutes
Rapid review of essential facts on monkeypox Uploaded 23-05-22 Monkeypox Key facts https://www.who.int/news-room/fact-sheets/detail/monkeypox Cases around the world, therefore sped for past few weeks Severe cases occur more commonly among children https://www.telegraph.co.uk/news/2022/05/20/monkeypox-outbreak-doubles-health-authorities-set-announce-11/ Transmission Contact with an infected animal or human Respiratory droplets Lesions Skin contact Broken skin Bodily fluids Mucous membranes Contaminated materials, bed linens, clothing, towels Fomites NHSE High Consequence Infection Diseases (airborne) Network / WHO Incubation, 6 to 13 days https://www.gov.uk/government/news/monkeypox-case-confirmed-in-england-1 https://www.nhs.uk/conditions/monkeypox/ https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON381 https://www.who.int/emergencies/outbreak-toolkit/disease-outbreak-toolboxes/monkeypox-outbreak-toolbox An acute illness with fever more than 38.3⁰C (101⁰F) Chills Intense headache Prodromal lymphadenopathy Back pain and muscle aches Myalgia and intense asthenia Followed one to three days later by a progressively developing rash, often beginning on the face (most dense), and then spreading elsewhere on the body, including soles of feet and palms of hands. Symptomatic, then rash, 1 to 5 days after first symptoms The rash changes and goes through different stages before finally forming a scab, which later falls off. (can look like chickenpox or syphilis) Starts as raised spots, forming into fluid filled blisters, then scabs which fall off Lesions can be very itchy or painful Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
October 24 · 13 min
Modification in death stats
Massive APPARENT reduction in excess deaths in 2023 as UK ONS change how they calculate excess deaths. https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/causesofdeath/articles/estimatingexcessdeathsintheukmethodologychanges/latest OECD, UK https://stats.oecd.org/index.aspx?queryid=104676 Excess deaths in 2022, 52,514 (9.26%) OECD, UK, weeks 1 – 44, 2023 Excess deaths, 49,389 (9.44%) https://www.gov.uk/government/organisations/office-for-health-improvement-and-disparities/about/statistics https://app.powerbi.com/view?r=eyJrIjoiYmUwNmFhMjYtNGZhYS00NDk2LWFlMTAtOTg0OGNhNmFiNGM0IiwidCI6ImVlNGUxNDk5LTRhMzUtNGIyZS1hZDQ3LTVmM2NmOWRlODY2NiIsImMiOjh9 Early heart disease deaths rise to 14-year high https://www.bhf.org.uk/what-we-do/news-from-the-bhf/news-archive/2024/january/early-heart-disease-deaths-rise-to-14-year-high Over 100,000 excess deaths involving cardiovascular conditions in England since February 2020 Heart and circulatory diseases cause around a quarter of all deaths in England – over 140,000 deaths each year or one death every four minutes. In 2022 Over 39,000 people in England died prematurely of cardiovascular conditions, heart attacks, coronary heart disease and stroke, an average of 750 people each week. It is the highest annual total since 2008. Learn more about your ad choices. Visit megaphone.fm/adchoices
October 24 · 14 min
We learn about alcohol
Professor David Nutt, doctor, psychiatrist, neuropsychopharmacologist, addiction specialist, medical author and researcher. Leading expert on brain chemistry, the effects of alcohol, and the GABA system. Uploaded 03-06-25 This video is a clip from this full interview, https://studio.youtube.com/video/ocSPQp49DtQ/edit Link for Sentia drinks, https://sentiaspirits.com/ David founded SENTIA Spirits to achieve his vision of bringing safer, better choices to adult social drinkers. Link for Drink? UK link, https://www.amazon.co.uk/Drink-Science-Alcohol-Your-Health/dp/B07YX52JLR/ref=sr_1_1?crid=2CICWKTQ2JV3G&dib=eyJ2IjoiMSJ9.aJAoDtBh4cjOSqJe7adChK_tZ8CwQp9YPQgbUer7xKcLmQkqz0biMtFM8Y3SUkzDruAr8hJg8aYyAswq90VrTNa58iL58pFzQJncYJqifnXS3KB0vvalvEqbygogaLqs.G0fMPUA2osO5moD_aY8Vzk9joOSu5dyDJl-Vhk9EdYc&dib_tag=se&keywords=drink+david+nutt&qid=1747172137&sprefix=drink+david+nutt%2Caps%2C91&sr=8-1 US link, https://www.amazon.com/Drink-New-Science-Alcohol-Health/dp/030692384X/ref=sr_1_1?crid=3JE2731TAQ8JO&dib=eyJ2IjoiMSJ9.mwR5QFRJgtmJUODgz0GYy90h23yRviakZe71yl9_qLDGjHj071QN20LucGBJIEps.3Y7Z7ETTPt0FcJL_3WHhXDz5YJUe9HAp3qA3pzkdYoM&dib_tag=se&keywords=drink+david+nutt&qid=1747172435&sprefix=drink+david+nutt%2Caps%2C176&sr=8-1 Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
October 24 · 24 min
Natural immunity preserves
Download free high-res PDFs of the posters, download free copies of my two text books. Any donations using this link help the work of campbell teaching. https://drjohncampbell.co.uk/ I taught bespoke health care as a fundamental principle for decades. Does natural and hybrid immunity obviate the need for frequent vaccine boosters against SARS-CoV-2 in the endemic phase? https://pubmed.ncbi.nlm.nih.gov/36366946/ https://onlinelibrary.wiley.com/doi/10.1111/eci.13906 Stefan Pilz John PA Ioannidis The coronavirus disease 2019 (COVID-19) pandemic has entered its endemic phase We observe significantly declining infection fatality rates due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Now It is crucial but challenging to define current and future vaccine policy, in a population with a high immunity against SARS-CoV-2, conferred by previous infections and/or vaccinations. Vaccine policy must consider the magnitude of the risks conferred by new infection(s), with current and evolving SARS-CoV-2 variants, how these risks vary in different groups of individuals, how to balance these risks against the apparently small, but existent, risks of harms of vaccination, and the cost-benefit of different options. More evidence from randomized controlled trials, and continuously accumulating national health data is required, to inform shared decision-making with people who consider vaccination options. Vaccine policy makers should cautiously weight what vaccination schedules are needed, and refrain from urging frequent vaccine boosters unless supported by sufficient evidence. The key issue Whether and how to consider natural immunity after SARS-CoV-2 infections, and hybrid immunity It is very likely that the large majority of the global population has been infected with SARS-CoV-2, at least once by late 2022 (Excluding China) People who have never been infected have probably become a rarity. It is well established that previous SARS- CoV-2 infections induce a significant and long-lasting protection against reinfections, and even more so against severe COVID-19.3-6 Lets check the evidence https://pubmed.ncbi.nlm.nih.gov/35904405/ Risk of reinfection and disease after SARS-CoV-2 primary infection: Meta-analysis 91 studies, n = 15,034,624 Infections n = 158,478 reinfections During the first 3 months of Omicron wave, the reinfection rates reached 3.31%. Overall rates of severe/lethal COVID-19 were very low, (2-7 per 10,000), and were not affected by strain predominance. Conclusions A strong natural immunity follows the primary infection and may last for more than one year, suggesting that the risk and health care needs of recovered subjects might be limited. Although the reinfection rates considerably increased during the Omicron wave, the risk of a secondary severe or lethal disease remained very low. The risk-benefit profile of multiple vaccine doses for this subset of population needs to be carefully evaluated. Back to Pilz, PA loannidis paper Compared to vaccination by two doses, natural immunity was associated with a significantly higher protection against SARS-CoV-2 infections before the emergence of Omicron, when identical times have elapsed since the last immune conferring event. Denmark Little viral spread until late 2021, and then massive infections with Omicron, ensued in a population that had been widely vaccinated. Omicron infection fatality rate (IFR) until mid-March 2022, 6.2 per 100,000 infections, among apparently healthy people 17-72 years Compared to previous infection waves in Denmark, there was a very significant decline in IFR Omicron wave In populations with substantial prior exposure to SARS-CoV-2, re-infections, less than a quarter of the hospitalization risk, and one-tenth the mortality Vojvodina, Serbia 1% of re-infections requ Learn more about your ad choices. Visit megaphone.fm/adchoices

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