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Wes Roth

Wes Roth

Artificial Intelligence, AI, Machine Learning, Google DeepMind, OpenAI, ChatGPT, Anthropic, Tech, Coding, AI News, Large Language Models and... (most importantly)... optimism.

AGI rolls around only once. Let's make the best of it.

On this channel, my goal is to help everyone understand AI and it's implications better. To prepare for what's coming next.

The most important rule is "Don't Panic".

The second rule is keep learning.

Thank you for joining me for this ride.

-Wes Roth

Want to work with me?
Brand, sponsorship & business inquiries: wesroth@smoothmedia.co

Links:
Natural 20: https://natural20.com/

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  • 217 episodes
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  • October 20 · 35 min

    Microsoft JUST BROKE OpenAI...

    The latest AI News. Learn about LLMs, Gen AI and get ready for the rollout of AGI. Wes Roth covers the latest happenings in the world of OpenAI, Google, Anthropic, NVIDIA and Open Source AI. ______________________________________________ My Links 🔗 ➡️ Twitter: https://x.com/WesRoth ➡️ AI Newsletter: https://natural20.beehiiv.com/subscribe Want to work with me? Brand, sponsorship & business inquiries: wesroth@smoothmedia.co Check out my AI Podcast where me and Dylan interview AI experts: https://www.youtube.com/playlist?list=PLb1th0f6y4XSKLYenSVDUXFjSHsZTTfhk ______________________________________________ 00:00 AI news 02:29 Microsoft HUGE AI Releases 19:36 OpenClaw and Microsoft #ai #openai #llm Learn more about your ad choices. Visit megaphone.fm/adchoices

  • October 20 · 44 min

    AI News is Getting *WEIRD* Human Brain Matter in Chips. OpenAI tutorial. Amazon unleashed it's AI.

    #ai #openai #neuralink 🔥 Get my A.I. + Business Newsletter (free): https://natural20.com/ [DISHBRAIN] The human brain/computer interface: https://corticallabs.com/ https://newatlas.com/computers/human-brain-chip-ai/ https://www.youtube.com/watch?v=bEXefdbQDjw Amazon https://venturebeat.com/ai/amazon-grows-generative-ai-efforts-with-bedrock-expansion-for-aws/ Creating an automated meeting minutes generator with Whisper and GPT-4 https://platform.openai.com/docs/tutorials/meeting-minutes Money on Autopilot: The Future of AI x Personal Finance https://a16z.com/2023/07/27/money-on-autopilot-ai-personal-finance/ TIMELINE] [00:00] Intro [01:05] How the Human Brain Works [03:25] DishBrain [07:47] Can it play Doom? [11:41] OpenAI [17:31] Amazon [29:22] Auto Money [35:00] My Mission Learn more about your ad choices. Visit megaphone.fm/adchoices

  • October 20 · 26 min

    we JUST figured out how AI thinks

    The latest AI News. Learn about LLMs, Gen AI and get ready for the rollout of AGI. Wes Roth covers the latest happenings in the world of OpenAI, Google, Anthropic, NVIDIA and Open Source AI. ______________________________________________ My Links 🔗 ➡️ Twitter: https://x.com/WesRoth ➡️ AI Newsletter: https://natural20.beehiiv.com/subscribe Want to work with me? Brand, sponsorship & business inquiries: wesroth@smoothmedia.co Check out my AI Podcast where me and Dylan interview AI experts: https://www.youtube.com/playlist?list=PLb1th0f6y4XSKLYenSVDUXFjSHsZTTfhk ______________________________________________ #ai #openai #llm Learn more about your ad choices. Visit megaphone.fm/adchoices

  • October 20 · 22 min

    GPT-5.6 about to DROP

    The latest AI News. Learn about LLMs, Gen AI and get ready for the rollout of AGI. Wes Roth covers the latest happenings in the world of OpenAI, Google, Anthropic, NVIDIA and Open Source AI. ______________________________________________ My Links 🔗 ➡️ Twitter: https://x.com/WesRoth ➡️ AI Newsletter: https://natural20.beehiiv.com/subscribe Want to work with me? Brand, sponsorship & business inquiries: wesroth@smoothmedia.co Check out my AI Podcast where me and Dylan interview AI experts: https://www.youtube.com/playlist?list=PLb1th0f6y4XSKLYenSVDUXFjSHsZTTfhk ______________________________________________ #ai #openai #llm Learn more about your ad choices. Visit megaphone.fm/adchoices

  • October 20 · 41 min

    Anthropic Calls for "Global AI Pause"

    The latest AI News. Learn about LLMs, Gen AI and get ready for the rollout of AGI. Wes Roth covers the latest happenings in the world of OpenAI, Google, Anthropic, NVIDIA and Open Source AI. ______________________________________________ My Links 🔗 ➡️ Twitter: https://x.com/WesRoth ➡️ AI Newsletter: https://natural20.beehiiv.com/subscribe Want to work with me? Brand, sponsorship & business inquiries: wesroth@smoothmedia.co Check out my AI Podcast where me and Dylan interview AI experts: https://www.youtube.com/playlist?list=PLb1th0f6y4XSKLYenSVDUXFjSHsZTTfhk ______________________________________________ #ai #openai #llm Learn more about your ad choices. Visit megaphone.fm/adchoices

  • October 20 · 37 min

    OpenAI Q* might be REVOLUTIONARY AI TECH | Biggest thing since Transformers | Researchers *spooked*

    AI is getting faster, better. [1hr Talk] Intro to Large Language Models Andrej Karpathy https://www.youtube.com/watch?v=zjkBMFhNj_g&t=2415s Q* Hypothesis https://www.interconnects.ai/p/q-star q* proved p==np https://twitter.com/Plinz/status/1728668801791897732 LEAKED DOC (maybe fake, no proof) https://www.reddit.com/r/singularity/comments/1824o9c/is_this_leaked_explanation_of_what_ilya_saw_real/ OpenAI RL Docs: https://spinningup.openai.com/en/latest/user/introduction.html Playing Atari with Deep Reinforcement Learning: https://www.cs.toronto.edu/~vmnih/docs/dqn.pdf Get on my daily AI newsletter 🔥 https://natural20.beehiiv.com/subscribe [News, Research and Tutorials on AI] See more at: https://natural20.com/ My AI Playlist: https://www.youtube.com/playlist?list=PLb1th0f6y4XROkUAwkYhcHb7OY9yoGGZH Learn more about your ad choices. Visit megaphone.fm/adchoices

  • October 20 · 34 min

    it JUST happened

    My Links 🔗 ➡️ Twitter: https://x.com/WesRoth ➡️ AI Newsletter: https://natural20.beehiiv.com/subscribe ➡️ Sponsorship inquiries: wesroth@smoothmedia.co ______________________________________________ Something Big Is Happening https://x.com/mattshumer_/status/2021256989876109403 Check out my AI Podcast where me and Dylan interview AI experts: https://www.youtube.com/playlist?list=PLb1th0f6y4XSKLYenSVDUXFjSHsZTTfhk #ai #openai #llm Learn more about your ad choices. Visit megaphone.fm/adchoices

  • October 20 · 14 min

    AI bubble JUST popped...

    The latest AI News. Learn about LLMs, Gen AI and get ready for the rollout of AGI. Wes Roth covers the latest happenings in the world of OpenAI, Google, Anthropic, NVIDIA and Open Source AI. ______________________________________________ My Links 🔗 ➡️ Twitter: https://x.com/WesRoth ➡️ AI Newsletter: https://natural20.beehiiv.com/subscribe Want to work with me? Brand, sponsorship & business inquiries: wesroth@smoothmedia.co Check out my AI Podcast where me and Dylan interview AI experts: https://www.youtube.com/playlist?list=PLb1th0f6y4XSKLYenSVDUXFjSHsZTTfhk ______________________________________________ #ai #openai #llm Learn more about your ad choices. Visit megaphone.fm/adchoices

  • October 20 · 42 min

    OpenAI Assistants API to Build AI Agent SWARMS. Better than AutoGen?

    My GPT for building Assistants: https://chat.openai.com/g/g-uMLDryp2X-assistant-coder-build-autonomous-ai-assistants (EARLY BETA) (work in progress) Get on my daily AI newsletter 🔥 https://natural20.beehiiv.com/subscribe [News, Research and Tutorials on AI] Video Summary This video provides an insightful tutorial on creating AI assistants using OpenAI's API. The video begins by discussing the significance of the recent OpenAI developer conference, highlighting two key announcements: GPTs (customizable AI models) and AI assistants. It emphasizes how GPTs, while powerful, have specific limitations to prevent autonomous operations without user prompts. The focus then shifts to creating AI assistants through API calls, demonstrating this with practical coding examples. The presenter uses Google Colab and OpenAI's API to create a simple application that analyzes stock prices and performs text analysis with GPT models. The video further explores the potential of AI assistants, explaining how to create, modify, and interact with them, including managing their roles and functionalities. The presenter emphasizes the educational aspect, aiming to bridge the gap for viewers with limited coding experience. Additionally, the video covers advanced topics such as thread creation, message handling, and using tools like Code Interpreter for enhanced assistant capabilities. The tutorial concludes with a preview of upcoming features in the OpenAI API, including multi-modal capabilities and real-time application support. Video Chapters [00:00:00] Introduction Overview of the OpenAI Developer Conference Discussion of GPTs and AI assistants [00:01:00] GPTs and Limitations Explanation of GPTs' power and restrictions Preventing autonomous operations [00:02:00] Creating AI Assistants Introduction to creating assistants with API calls Demonstrating simple application for stock analysis [00:03:00] Setting up Google Colab Step-by-step setup of Google Colab for coding [00:04:00] Using ChatGPT for Code Generation Leveraging ChatGPT to generate code for the application [00:05:00] Assistant Coder Development Developing an AI assistant for coding assistance [00:10:00] Practical Coding Example Real-time coding example using stock data [00:12:00] Interacting with AI Assistants Managing and modifying AI assistants' roles and functions [00:15:00] Advanced Assistant Management Creating threads and handling messages in assistants [00:17:00] Utilizing Tools in Assistants Using tools like Code Interpreter for enhanced functionalities [00:20:00] Future API Features Preview of upcoming features in OpenAI API [00:22:00] Conclusion and Q&A Summarizing key points and addressing viewer questions See more at: https://natural20.com/ My AI Playlist: https://www.youtube.com/playlist?list=PLb1th0f6y4XROkUAwkYhcHb7OY9yoGGZH Learn more about your ad choices. Visit megaphone.fm/adchoices

  • October 20 · 32 min

    everyone JUST got HACKED...

    The latest AI News. Learn about LLMs, Gen AI and get ready for the rollout of AGI. Wes Roth covers the latest happenings in the world of OpenAI, Google, Anthropic, NVIDIA and Open Source AI. LINKS: Apple’s Security Has Been Tough to Crack. Mythos Helped Find a Way In. https://www.wsj.com/tech/ai/anthropic-mythos-apple-macos-bug-339da403 GTIG AI Threat Tracker: Adversaries Leverage AI for Vulnerability Exploitation, Augmented Operations, and Initial Access https://cloud.google.com/blog/topics/threat-intelligence/ai-vulnerability-exploitation-initial-access Microsoft’s multi-agent AI system tops Anthropic’s Mythos on cybersecurity benchmark https://www.geekwire.com/2026/microsofts-multi-agent-ai-system-tops-anthropics-mythos-on-cybersecurity-benchmark/ Exclusive: Palo Alto Networks says new AI models found 7x more vulnerabilities https://www.axios.com/2026/05/13/palo-alto-networks-mythos-gpt-cybersecurity ______________________________________________ My Links 🔗 ➡️ Twitter: https://x.com/WesRoth ➡️ AI Newsletter: https://natural20.beehiiv.com/subscribe Want to work with me? Brand, sponsorship & business inquiries: wesroth@smoothmedia.co Check out my AI Podcast where me and Dylan interview AI experts: https://www.youtube.com/playlist?list=PLb1th0f6y4XSKLYenSVDUXFjSHsZTTfhk ______________________________________________ #ai #openai #llm Learn more about your ad choices. Visit megaphone.fm/adchoices

  • October 20 · 9 min

    GPT 5 release date 🔥 might be closer than we think | OpenAI applies for GPT-5 Trademark in the US.

    #gpt5 #openai #gpt4 🔥 Get my A.I. + Business Newsletter (free): https://natural20.com/ [RELATED VIDEOS] Minecraft AI - SELF-IMPROVING 🤯 autonomous agent: https://www.youtube.com/watch?v=7yI4yfYftfM 25 ChatGPTs play a videogame... https://youtu.be/GwsRu9yLXnw GPT-4 leaked! 🔥 All details exposed 🔥 It is over... https://youtu.be/GwsRu9yLXnw LLMs as Tool Makers [LATM] - GPT-4 *UPGRADES* lower AI Models. https://www.youtube.com/watch?v=qWI1AJ2nSDY Sam Altman on UBI and Massive Job Losses from AI Automation https://www.youtube.com/watch?v=5Nsqv3FWXio Learn more about your ad choices. Visit megaphone.fm/adchoices

  • October 20 · 17 min

    AI in 2026 is going to be wild

    The latest AI News. Learn about LLMs, Gen AI and get ready for the rollout of AGI. Wes Roth covers the latest happenings in the world of OpenAI, Google, Anthropic, NVIDIA and Open Source AI. ______________________________________________ My Links 🔗 ➡️ Twitter: https://x.com/WesRoth ➡️ AI Newsletter: https://natural20.beehiiv.com/subscribe Want to work with me? Brand, sponsorship & business inquiries: wesroth@smoothmedia.co Check out my AI Podcast where me and Dylan interview AI experts: https://www.youtube.com/playlist?list=PLb1th0f6y4XSKLYenSVDUXFjSHsZTTfhk ______________________________________________ #ai #openai #llm Learn more about your ad choices. Visit megaphone.fm/adchoices

  • October 20 · 36 min

    this is the ONLY AI skill you need to have (seriously)

    Ready to build a site that looks hand-coded without hiring a developer? Launch your site for free at: https://framer.link/WesRoth use code WESROTH for a free month on Framer Pro. ______________________________________________ My Links 🔗 ➡️ Twitter: https://x.com/WesRoth ➡️ AI Newsletter: https://natural20.beehiiv.com/subscribe Want to work with me? Brand, sponsorship & business inquiries: wesroth@smoothmedia.co Check out my AI Podcast where me and Dylan interview AI experts: https://www.youtube.com/playlist?list=PLb1th0f6y4XSKLYenSVDUXFjSHsZTTfhk ______________________________________________ 00::00 AI Overwhelm 04:46 FRAMER (sponsor) 07:22 the ONLY app you need 19:00 the ONLY skill you need #ai #openai #llm Learn more about your ad choices. Visit megaphone.fm/adchoices

  • October 20 · 41 min

    "1,000 days left" Anthropic founder

    Jack Clark: https://jack-clark.net/2026/05/04/import-ai-455-automating-ai-research/ ______________________________________________ My Links 🔗 ➡️ Twitter: https://x.com/WesRoth ➡️ AI Newsletter: https://natural20.beehiiv.com/subscribe Want to work with me? Brand, sponsorship & business inquiries: wesroth@smoothmedia.co Check out my AI Podcast where me and Dylan interview AI experts: https://www.youtube.com/playlist?list=PLb1th0f6y4XSKLYenSVDUXFjSHsZTTfhk ______________________________________________ #ai #openai #llm Learn more about your ad choices. Visit megaphone.fm/adchoices

  • October 20 · 14 min

    Illumina AI - ChatGPT for your genome...

    🔥 Get my A.I. + Business Newsletter (free): https://natural20.com/ #genomesequencing #ai #deepmind TIMELINE 00:00 Advancements in AI 00:25 AlphaFold2 05:24 Increasing Interest 08:34 Illumina's PrimateAI 3D So Illumina unveils AI software to predict disease-causing genetic mutations in patients. The AI boom has been mostly centered around the big AI companies NVIDIA, GOOGLE, MICROSOFT, OPENAI etc That’s the space that everyone is watching. That’s where all the institutional money is flowing, but there is something else brewing just out of sight. First, it’s important to understand how Google’s DeepMind solved protein folding. And people are noticing this. More and more attention is being paid to the biotech companies where neural networks can be used to accelerate progress. People in this space believe that massive progress will be unlocked at the intersection of AI and Genetics. Neural Networks are great at swallowing large, unmanageable amounts of raw data and spitting out valuable insights. And that’s what a big part of Genomics is. It’s vast amounts of data. That brings us back to Illumina. It’s a massive company that is a global leader in genomic sequencing. Genomic sequencing, is very basically, the process of making DNA readable. So let’s say you have a blood sample or a spit sample, you run it through a machine to sequence it and on the other side you get the exact structure of your DNA. Actual data you can read, print out on a piece of paper or feed into a database. And there are now global efforts to sequence everyone and use AI to process the data. And some smart people are taking note Peter Thiel is a German-American billionaire entrepreneur, co-founder of PayPal, Palantir Technologies, and Founders Fund, he was the first outside investor in Facebook. And he’s investing in Ultima genomics, a competitor to Illumina. “Ultima Genomics is coming out of stealth mode after raising $600 million from investors including Andreessen Horowitz, Peter Thiel’s Founder Fund…” This was in 2022 Carl Icahn, the billionaire corporate Raider launched an attack on Illumina, buying up shares and trying to land some board seats. This was 2023 Stanley Druckenmiller, who is considered one of the best investors of all time, recently added $25 million of Illumina to this portfolio. This was May 2023, but this might be a lot more since there is a delay before they have to disclose their positions. Now, a couple of points I have to make here. One I own Illumina Shares, full disclaimer. Two, I can’t predict stock price, I don’t pay attention to the price. I just think “what would Warren Buffett do” and buy great companies and hold them forever. With that said, I feel like we are going to start seeing more action in this space. Bio-tech, specifically bio tech where AI can play a big role, will start growing at a faster rate. Genomics, personalized medicine, modified organisms etc. Learn more about your ad choices. Visit megaphone.fm/adchoices

  • October 20 · 32 min

    Google Deepmind RT 2 - Using LLMs to Build Thinking, Learning Robots

    #deepmind #ai #robotics 🔥 Get my A.I. + Business Newsletter (free): https://natural20.com/ [LINKS] https://www.deepmind.com/blog/rt-2-new-model-translates-vision-and-language-into-action https://robotics-transformer2.github.io/assets/rt2.pdf https://openai.com/research/gpt-4 https://www.understandingai.org/p/large-language-models-explained-with https://voyager.minedojo.org/assets/documents/voyager.pdf https://twitter.com/DrJimFan [MENTIONED VIDEOS] Minecraft AI - SELF-IMPROVING 🤯 autonomous agent: https://www.youtube.com/watch?v=7yI4yfYftfM LLMs as Tool Makers [LATM] - GPT-4 *UPGRADES* lower AI Models. https://www.youtube.com/watch?v=qWI1AJ2nSDY Sam Altman on UBI and Massive Job Losses from AI Automation https://www.youtube.com/watch?v=5Nsqv3FWXio [TIMELINE] [00:00] Intro [02:04] Using LLMs as a "brain" [05:28] Robotic Control [09:03] What's the Point?! [12:40] The Paper [18:15] Dr Jim Fan [19:30] Examples and Limitations [22:59] Training in Simulations Learn more about your ad choices. Visit megaphone.fm/adchoices

  • October 19 · 24 min

    Mythos 5 is WILD...

    LINKS etc: https://natural20.beehiiv.com/p/mythos-5-just-got-released ______________________________________________ My Links 🔗 ➡️ Twitter: https://x.com/WesRoth ➡️ AI Newsletter: https://natural20.beehiiv.com/subscribe Want to work with me? Brand, sponsorship & business inquiries: wesroth@smoothmedia.co Check out my AI Podcast where me and Dylan interview AI experts: https://www.youtube.com/playlist?list=PLb1th0f6y4XSKLYenSVDUXFjSHsZTTfhk ______________________________________________ #ai #openai #llm Learn more about your ad choices. Visit megaphone.fm/adchoices

  • October 19 · 22 min

    GPT 5.4 leaks

    The latest AI News. Learn about LLMs, Gen AI and get ready for the rollout of AGI. Wes Roth covers the latest happenings in the world of OpenAI, Google, Anthropic, NVIDIA and Open Source AI. ______________________________________________ My Links 🔗 ➡️ Twitter: https://x.com/WesRoth ➡️ AI Newsletter: https://natural20.beehiiv.com/subscribe Want to work with me? Brand, sponsorship & business inquiries: wesroth@smoothmedia.co Check out my AI Podcast where me and Dylan interview AI experts: https://www.youtube.com/playlist?list=PLb1th0f6y4XSKLYenSVDUXFjSHsZTTfhk ______________________________________________ #ai #openai #llm Learn more about your ad choices. Visit megaphone.fm/adchoices

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