

Aqua Tofana: Avon Ladies of Doom
Aqua Tofana was a clear, nearly tasteless poison sold to women in 17th-century Italy. Linked to Giulia Tofana and later Geronima Spana, it became the center of a deadly Roman poisoning scandal involving abused wives, wealthy noblewomen, secret couriers, and papal investigators. This episode follows the rise of the Aqua Tofana poison network, the 1659 Spana prosecution, the executions at Campo de’ Fiori, and the legends that later distorted the case. We also examine how marriage laws, class, gender, and the plague helped the poison spread through Rome. ............................................... Links: Website: timeandtalespodcast.com Email: timeandtalespodcast@gmail.com YouTube: https://www.youtube.com/@LMRiviere .............................................. Sources: Buchanan, Ashley. “‘One Drop to Heal, Three Drops to Kill’: Women and Early Modern Poison.” Folger Shakespeare Library, 24 Oct. 2025. Feci, Simona. “Trame di donne all’indomani della peste romana del 1656. La vicenda dell’«acqua tofana».” Mélanges de l’École française de Rome - Italie et Méditerranée modernes et contemporaines, vol. 132, no. 1, 2020, pp. 59–71. Feci, Simona. L’acquetta di Giulia: Mogli avvelenatrici e mariti violenti nella Roma del Seicento. Viella, 2024. Monson, Craig A. The Black Widows of the Eternal City: The True Story of Rome’s Most Infamous Poisoners. University of Michigan Press, 2020. Zaleski, Erin. “Did Giulia Tofana Kill Hundreds of Men in Renaissance Italy?” National Geographic, 10 July 2026. Archivio di Stato di Roma. “L’Acqua Tofana – Mogli avvelenatrici nella Roma del ‘600.” Ministero della Cultura, 16 May 2025. “Giulia Tofana.” Wikipedia: The Free Encyclopedia. Wikimedia Foundation. “Spana Prosecution.” Wikipedia: The Free Encyclopedia. Wikimedia Foundation.
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