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The Stem Cell Podcast

The Stem Cell Podcast

A podcast dedicated to culturing knowledge in stem cell research. Brought to you by STEMCELL Technologies.

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  • 357 episodes
  • Updated July 21

Episodes357

Newest first
  • Apr 8, 2014 · 1 hr 12 min

    Ep. 16: Stem Cell Scientist in Washington?

    Guest: In this episode we bring on Dr. Raja Kittappa, a stem cell scientist who has recently decided to leave science and run for congress. Resources and Links Brain Activation during Human Male Ejaculation Experimental Cancer Drug Reverses Schizophrenia in Adolescent Mice First Synthetic Yeast Chromosome Revealed Party Drug Ketamine Could Help People with Severe Depression Experimental Compound FRAX486 Reverses Signs of Fragile X In Mice Researchers Identify Good Bacteria That Protects against HIV MIT Researchers Develop Living Material Using E. coli Disorganized Cortical Patches Suggest Prenatal Origin of Autism Blood Test of 4 Biomarkers Predicts Death within 5 Years Gene Family Linked To Brain Evolution Implicated in Severity of Autism Symptoms HPV-Linked Throat Cancer May Have Telltale First Symptoms Mugshots Built from DNA Data Genetic Factor Contributes to Forgetfulness Study: Climate Change Accelerates Greenland Ice Loss Gene Editing of CCR5 in Autologous CD4 T Cells of Persons Infected with HIV Human Nose Can Detect More Than 1 Trillion Smells, Scientists Discover Scientists Find Gene Which Is Linked to Exceptionally Low IQ in Children Stem Cell Scientist Guilty of Falsifying Data Ancient Virus DNA Gives Stem Cells the Power to Transform Modeling ALS with iPSCs Reveals that Mutant SOD1 Misregulates Neurofilament Balance in Motor Neurons Intrinsic Membrane Hyperexcitability of Amyotrophic Lateral Sclerosis Patient-Derived Motor Neurons Telomerase Protects Werner Syndrome Lineage-Specific Stem Cells from Premature Aging Mouse SCNT ESCs Have Lower Somatic Mutation Load Than Syngeneic iPSCs Dynamics of HSPC Repopulation in Nonhuman Primates Revealed by a Decade-Long Clonal-Tracking Study Combined Hydrogels That Switch Human Pluripotent Stem Cells From Self-Renewal to Differentiation Mutations in USP9X Are Associated with X-Linked Intellectual Disability and Disrupt Neuronal Cell Migration and Growth Photo Reference: Courtesy of Dr. Raja Kittappa Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

  • Mar 21, 2014 · 1 hr 13 min

    Ep.15: Melanoma and Zebrafish Featuring Dr. Leonard Zon

    Guest: In this episode, we bring on an internationally recognized stem cell and cancer researcher Dr. Leonard Zon from Harvard Medical School and Boston Children’s Hosital. Dr. Zon talks to us about his work using zebrafish as a model to study cancer and melanoma and tells some really funny stories on his experiences with these fish. Resources and Links Trends In Atmospheric Carbon Dioxide In Mauna Loa, Hawaii Gel Protects Monkeys from H.I.V. after Sex, Study Finds Genetic Modification and Screening in Rat Using Haploid Embryonic Stem Cells Telescope Captures View of Gravitational Waves Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation Environmental and State-Level Regulatory Factors Affect the Incidence of Autism and Intellectual Disability Respiratory Failure, Cleft Palate and Epilepsy in the Mouse Model of Human Xq22.1 Deletion Syndrome CDC Warns Untreatable Gonorrhea Could Spread Like Wildfire In Rare Case, Woman with H.I.V. Infects Female Sex Partner, C.D.C. Says Obesity-Associated Variants within FTO Form Long-Range Functional Connections with IRX3 Hydrous Mantle Transition Zone Indicated By Ringwoodite Included within Diamond Human C-Tactile Afferents Are Tuned to the Temperature of a Skin-Stroking Caress Shorter Telomeres with High Telomerase Activity are Associated with Raised Allostatic Load and Impoverished Psychosocial Resources Biomarkers Could Predict Alzheimer’s Before It Starts Confusions About Totipotency: Stem Cells Are Not Embryos Mechanical Memory and Dosing Influence Stem Cell Fate Cell-Autonomous Correction of Ring Chromosomes in Human Induced Pluripotent Stem Cells C9orf72 Nucleotide Repeat Structures Initiate Molecular Cascades of Disease Haematopoietic Stem Cells Require a Highly Regulated Protein Synthesis Rate High-Efficiency Motor Neuron Differentiation from Human Pluripotent Stem Cells and the Function Ofislet-1 Photo Reference: Courtesy of Dr. Leonard Zon Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

  • Mar 10, 2014 · 1 hr 7 min

    Ep.14: Direct Reprogramming Featuring Dr. Justin Ichida

    Guest: Over the past few weeks some really exciting papers came out describing the reprogramming of one cell into another, a process called Direct Reprogramming. On this episode we talk to Dr. Justin Ichida from the University of Southern California who uses the latest reprogramming techniques in his lab to study neural disease. His current research is focused on using patient-specific disease models to define the mechanisms that lead to neuronal loss in ALS and frontotemporal dementia. Resources and Links University of Southern California – The Ichida Lab – Board California Institute for Regenerative Medicine (CIRM) Center for Regenerative Medicine and Stem Cell Research Early Treatment Is Found to Clear H.I.V. in a Second Baby Why Can You Remember Your Dreams? Researchers Uncover Why Only Some People Can Recall Them in the Morning Acetaminophen In Pregnancy Linked to ADHD in Kids, Study Finds Study Uncovers New Pathway of Melanoma Metastasis New Research Finds Direct Connection Between Acupuncture and Processes That Alleviate Sepsis ‘Largest Ever’ Trial of Adult Stem Cells in Heart Attack Patients Begins This Company Wants to Make In Vitro Meat From Celebrities’ Stem Cells USPTO Issues Patent For Fraudulent Stem Cell Procedure Isolation Of Human Induced Pluripotent Stem Cell-Derived Dopaminergic Progenitors By Cell Sorting For Successful Transplantation Coordination Of Engineered Factors With TET1/2 Promotes Early-Stage Epigenetic Modification during Somatic Cell Reprogramming Small Molecules Facilitate the Reprogramming of Mouse Fibroblasts into Pancreatic Lineages Direct Reprogramming of Human Fibroblasts to Functional and Expandable Hepatocytes Human Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming Photo Reference: Courtesy of Dr. Justin Ichida Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

  • Feb 23, 2014 · 1 hr 9 min

    Ep. 13: STAP Stem Cells and Blogging Featuring Dr. Paul Knoepfler

    Guest: STAP stem cells were a new method of generating pluripotent stem cells published in a paper a few weeks ago. When it came out, scientists scratched their heads and wondered whether or not this new method could actually work and be reproducible. Well, while the jury is still out, it is not looking good and we bring on the show one of the most recognized voices of stem cell research, Dr. Paul Knoepfler to discuss the STAP stem cell theory. In addition to running a laboratory, Dr. Knoepfler maintains an amazingly active stem cell blog breaking all the latest stem cell news, and educating the public about stem cells. Resources and Links Knoepfler Lab Stem Cell Blog Stem Cells: An Insiders Guide by Paul Knoepfler Expandable Megakaryocyte Cell Lines Enable Clinically Applicable Generation of Platelets from Human Induced Pluripotent Stem Cells The Endocannabinoid System Controls Food Intake via Olfactory Processes Astrocyte-Derived Endothelin-1 Inhibits Remyelination through Notch Activation Rejuvenation of the Muscle Stem Cell Population Restores Strength to Injured Aged Muscles Nanog-Independent Reprogramming to iPSCs with Canonical Factors Nanog Is Dispensable for the Generation of Induced Pluripotent Stem Cells In Vivo Direct Reprogramming of Reactive Glial Cells into Functional Neurons after Brain Injury and in an Alzheimer’s Disease Model NPTX1 Regulates Neural Lineage Specification from Human Pluripotent Stem Cells Photo Reference: Courtesy of Dr. Paul Knoepfler Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

  • Feb 10, 2014 · 1 hr 17 min

    Ep. 12: Cancer and Stem Cells Featuring Dr. Sean Morrison

    Guest: In this episode, we interview another stem cell pioneer, Dr. Sean Morrison, who is internationally recognized for his work in understanding the mechanisms of stem cell regulatory mechanisms and how this is relevant in cancer. In the science roundup we cover zombie bees, stem cells for baldness, dipping cells in acid to make stem cells, and how to identify the difference between iPSCs and hESCs. Photo Reference: Courtesy of Dr. Chad Cowan Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

  • Jan 27, 2014 · 1 hr 18 min

    Ep. 11: Stem Cell Core Facilities Featuring Dr. Mark Tomishima

    Guest: Dr. Mark Tomishima, director of the SKI Stem Cell Research Facility located in New York City joins us for this episode. Dr. Tomishima tells us about what his and other core facilities do for stem cell researchers locally and abroad, as well as various projects his group is working on. We then go through the science roundup discussing everything from a new herpes drug, to heart cell propelled sperm looking bio-bots, to stem cell-derived 3D kidneys. Photo Reference: Courtesy of Dr. Mark Tomishima Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

  • Jan 14, 2014 · 1 hr 12 min

    Ep. 10: RPE and Macular Degeneration Featuring Dr. Sally Temple

    Guest: In this episode, we bring on a true pioneer in the stem cell field, Dr. Sally Temple, scientific director of the Neural Stem Cell Institute. Dr. Temple discovered that stem-like cells exist in the adult brain in the late 80s and has since gone on to characterize these cells extensively. Her group has recently discovered a novel stem cell in the eye that they plan to use as a new therapy for macular degeneration, the leading cause of blindness. In the science roundup we talk about everything from caffeine boosting memory, to the possibility of the Y chromosome disappearing. Photo Reference: Courtesy of Dr. Sally Temple Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

  • Jan 2, 2014 · 1 hr

    Ep. 9: 2013 Roundup

    Happy new year Stem Cell Podcast listeners, we are back to start off with an episode that looks backs at a year of science in 2013 and gives you our top 10 studies from both the stem cell world and science as a whole. We discuss a variety of topics from human cloning to going interstellar. It’s been a great year for science despite threats to funding. Let’s make sure science funding increases in 2014. Enjoy! Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

  • Dec 13, 2013 · 1 hr 7 min

    Ep. 8: Aged Neurons in a Dish Featuring Justine Miller

    Guest: Justine Miller, a PhD candidate from Lorenz Studer’s lab at Memorial Sloan Kettering, joins us to discuss her recent paper in Cell Stem Cell showing how to age stem cell-derived neurons in the culture dish. In our science round up, we discuss everything from the ground state in stem cells to male birth control. We then dive into other stem cell topics including reprogramming via protein transduction and CRISPR-mediated gene repair. Photo Reference: Courtesy of Justine Miller, PhD candidate Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

  • Nov 30, 2013 · 54 min

    Ep. 7: Holiday Science Break

    We are back with a stem cell “quickie” for the holidays. In our science round up we talk mummified ribs, fear of snakes, and genes associated with an increased risk of Alzheimer’s disease. We then discuss the latest stem cell news, papers, and a conference recently held in Los Angeles. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

  • Nov 20, 2013 · 1 hr 5 min

    Ep. 6: ALS and C9orf72 Featuring Dr. Asif Maroof

    Guest: We interview Dr. Asif Maroof, a post-doctoral fellow in the lab of Dr. Kevin Eggan at the Harvard Stem Cell Institute to talk about his latest paper in Nature Neuroscience describing a gene implicated in ALS a.k.a Lou Gehrig’s disease. Our science roundup includes new Alzheimer’s targets, bitter tasting genes, polio, and bacteria-fighting zinc. Photo Reference: Courtesy of Dr. Asif Maroof Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

  • Nov 9, 2013 · 1 hr 7 min

    Ep. 5: Parkinson’s Disease and Stem Cells

    In this episode we do things a little different. Since we both work on Parkinson’s disease we will not be featuring a guest. Instead, we will talk about the etiology of the disease and cover various forms of therapy – with an emphasis on stem cells. Our science roundup includes: CO2 levels, “Project Einstein”, paper retraction rates, SARS, and plexins. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

  • Oct 27, 2013 · 1 hr 5 min

    Ep. 4: 3D Pancreas and ISSCR Featuring Dr. Carl P. Wonders

    Guest: In this episode, we welcome Dr. Carl P. Wonders, the scientific affairs manager for the International Society for Stem Cell Research (ISSCR). We discuss the annual meeting, science outreach, and long-term goals for the society. Our science round-up segment includes: RNAi pesticides, atomic clocks, corked wine and TCA, and review of an open-access journal investigation. Photo Reference: Courtesy of Dr. Carl Wonders Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

  • Oct 16, 2013 · 1 hr 3 min

    Ep. 3: Blood From Stem Cells Featuring Dr. Daylon James

    Guest: In this episode, we interview stem cell biologist Dr. Daylon James to discuss the field of blood stem cells; different strategies and clinical implications. Our science round up this week includes the CTE issue in the NFL, Nobel laureates, and gut bacteria. Photo Reference: Courtesy of New York Social Diary Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

  • Oct 11, 2013 · 53 min

    Ep. 2: Reprogramming Brakes and Government Shutdown Featuring Dr. Jacob Hanna

    Guest: In this episode we welcome Dr. Jacob Hanna from Weizmann Institute of Science. Dr. Hanna’s group recently published in Nature describing a method for 100% reprogramming efficiency. We also do our usual Stem Cell Podcast roundup, which includes anti-acne bacteria, Eric Kandel’s RB-AB 48 Alzheimer’s target and others. Photo Reference: Courtesy of Dr. Jacob Hanna Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

  • Sep 28, 2013 · 47 min

    Ep. 1: In Vivo Reprogramming and Mini Brains Featuring Dr. Juergen Knoblich

    Guest: In this episode we start off with a quick general science news roundup before discussing two new papers in stem cell research. Both papers appeared in the journal Nature. The first describes a novel method of reprogramming somatic cells into induced pluripotent stem cells in vivo, and other describes a method to make a mini cerebral cortex from human embryonic stem cells. The senior author on the latter study, Dr. Juergen Knoblich, joins us to discuss this paper and its implications. Photo Reference: Courtesy of Dr. Juergen Knoblich Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

  • Sep 21, 2013 · 24 min

    Introduction

    Welcome to the stem cell podcast hosted by Dr.’s Christopher Fasano and Yosif Ganat. Here we will give a brief introduction to the biology of stem cells and the future direction of this podcast. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe