Episode 22: Are NAD Supplements Worth Trying?
In this episode, we dig into the viral buzz around NAD+ and its precursors and ask the big question: are supplements or IV “drips” actually worth it? We share a real patient story that captures why these promises feel so tempting—especially when you’re anxious, exhausted, or desperate to feel better. We also discuss the surprising gap between what’s commonly claimed online and what’s actually been studied, including what we found when we looked closely at the available research and the red flags that stood out. If you’ve been curious about NAD+ for energy, longevity, recovery, or “inflammation,” this is the nuanced, evidence-focused conversation you’ve been looking for. CORRECTION: In this episode we discussed the 2022 FDA ban on NMN being sold as a dietary supplement because it had been authorized for investigation as a drug. However, in September 2025, after industry petitions and a lawsuit, the FDA reversed this decision and concluded NMN can be marketed as a supplement after all. 00:00 Podcast Mission 01:18 NAD Episode Setup 01:44 Patient Brochure Story 05:35 Natural Versus Safe 07:37 Why NAD Is Trending 11:59 NAD Science Basics 13:54 Where NAD Comes From 15:49 Why NAD Matters 17:43 Human Evidence NR 20:28 Clinical Outcomes Matter 23:15 NR Trial Results 25:15 Long COVID Study 26:05 Switching To NMN 26:08 NMN vs NR Absorption 26:41 NMN Studies Overview 27:24 FDA Pulls NMN 28:12 NMN Results Reality Check 29:39 IV NAD No Evidence 30:16 Wellness Clinic Pilot Study 32:12 Infusion Side Effects 34:48 Flow Rate Red Flags 36:04 Labs Outcomes And Cost 38:47 Why IV Bars Are Risky 41:41 Clinical Takeaways 43:26 Patient Story Lupus Diagnosis 46:26 Wrap Up And Disclaimer To receive professional continuing education credits for listening to our episodes- visit www.theantidocialdoctors.com to subscribe. You will receive an email with each new episode including a link to the episode, a written summary, and a link to claim your CME/CEs. 📖 Read the full episode summary, sources, and resources on our Substack: 👉www.theantisocialdoctors.com
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