How Weight Loss Medications Actually Work in Your Body
Send us Fan Mail We break down the mechanism of action for GLP-1 receptor agonists like tirzepatide (Zepbound/Mounjaro) and semaglutide, explaining how these medications work in the body to regulate appetite and metabolism. • GLP-1 medications contain a C20 fatty diacid that binds to albumin, prolonging half-life • These drugs target both GIP and GLP-1 receptors to regulate appetite and caloric intake • Receptors are found in brain areas involved in appetite regulation and throughout the GI system • Pharmacodynamics include increased insulin sensitivity, reduced glucagon secretion, and delayed gastric emptying • Medications are absorbed subcutaneously with about 80% bioavailability • Distribution occurs throughout the body with 5-6 day half-life, explaining weekly dosing • Metabolism occurs primarily through the liver with excretion via urine • Common injection sites include arms, legs, stomach, or back (the "margarita" zones) Never do this on your own without real supervision. Everything has to be done safely, with a healthcare provider and someone that is aware of where you stand and how you are. Support the show Sponsor Affiliates Empowering Your Health https://www.atecam.com/ Get YOUR Own Joburg Protein Snacks Discount Code: Damaris15 Or Damaris18 Feeling need to Lose Weight & Become metabolically Healthy GET METABOLIC COURSE GLP 1 REseT This course is designed for individuals looking to optimize their metabolic health through integrative and functional medicine approaches. Whether you're on a GLP-1 medication or seeking natural ways to enhance your metabolic function, this course provides actionable steps, expert insights, and a personalized roadmap sustainable wellness. Are you feeling stressed, tired, or Metabolism imbalanced? Take advantage of our free mindful steps to help improve your well-being. ENJOY ONE OF our Books Mindful Ways Health Wealth & Life https://stan.store/Mindfullyintegrative Join Yearly membership ALL IN ONE FUNCTION HEALTH Ask Us for help with Medica...
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