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Lab to Lives · Dec 17, 2025 · 29 min

Inside Sionna’s Bid To Normalize CFTR Function

Send us Fan Mail Two leaders from Sionna Therapeutics walk through a 15‑year journey from Genzyme science to a public company advancing NBD1‑targeted therapies in cystic fibrosis. We examine why most patients still fall short of normal CFTR, how a predictive assay de‑risks choices, and what it takes to finance, hire, and execute with patients as the North Star. Visit: sionnatx.com Support the show ________ Reach out to Ivanna Rosendal Join the conversation on our LinkedIn page Visit www.labtolives.com Hosts Alexander Booth Chiara Chianese Ivanna Rosendal Oshida

0:00 · Setting The Mission And Guests-29:41

transcript

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show notes

Send us Fan Mail

Two leaders from Sionna Therapeutics walk through a 15‑year journey from Genzyme science to a public company advancing NBD1‑targeted therapies in cystic fibrosis. We examine why most patients still fall short of normal CFTR, how a predictive assay de‑risks choices, and what it takes to finance, hire, and execute with patients as the North Star.

Visit: sionnatx.com


Support the show


________
Reach out to Ivanna Rosendal

Join the conversation on our LinkedIn page

Visit www.labtolives.com 


Hosts

Alexander Booth

Chiara Chianese

Ivanna Rosendal Oshida 

links7

chapters

12 chapters