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Astral Codex Ten Podcast

Jeremiah

The official audio version of Astral Codex Ten, with an archive of posts from Slate Star Codex. It's just me reading Scott Alexander's blog posts.

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  • 51 episodes
  • Avg 33 min
  • English
Counted on this page — what you have heard stays on this device, so it is not something the list can be paged by.
  • Wednesday · 55 min

    Does Georgism Work? Five Years Later

    A guest post by Lars Doucet Hi, this is Lars Doucet, author of the book review of Henry George's Progress and Poverty that won the first ACX book review contest, as well as the three-part follow-up guest post series, "Does Georgism Work?" A lot has happened since then, including land value tax (LVT) enablement laws passing this year in two U.S. states and the election of LVT-friendly national leaders in the UK and South Korea. As for me, I now work full-time for the Center for Land Economics and write for Progress & Poverty substack. I'd like to reflect on what I wrote five years ago: what I was right about, what I've changed my mind on, and what the outlook for LVT is in 2026. But first, here's a brief summary for those who either have no idea what I'm talking about or just need a refresher. https://www.astralcodexten.com/p/does-georgism-work-five-years-later

  • Wednesday · 22 min

    The Specter Of Neuralese

    I. At Long Last, We Have Created Neuralese Recurrence, From The Classic Sci-Fi Novel "Don't Create Neuralese Recurrence" In the public debates after the release of AI 2027, some people accused us of misleading readers by positing "neuralese recurrence", a hypothetical technology that would allow AIs to think dangerous thoughts without getting detected. You'll never guess what happened earlier this month! https://www.astralcodexten.com/p/the-specter-of-neuralese

  • Wednesday · 19 min

    Mysteries Of AI Generalization

    I. Owain Evans In 2025, Owain Evans et al published a paper on "emergent misalignment". They trained a previously-aligned AI to do one immoral thing: write insecure code full of vulnerabilities and backdoors. To their surprise, the AI became immoral in general. Its advice to a bored user was to try taking random expired medications and see what happened. Its money-making tips all involved theft and violence. When asked for its favorite historic figure, it chose Hitler. Some co-authors followed up with additional weird discoveries. If you trained an AI to give the 19th-century names for birds (eg identify the American Pipit by its 19th-century name "Brown Titlark"), then the AI would behave like a 19th-century person in general (for example, assert that a woman's proper place is in the home). This sounds bad, in that random things can turn AIs evil or sexist. But some people in AI safety (including Eliezer Yudkowsky) speculated that in fact it was very, very good. We had feared that it would be impossible to align AIs to the Good. They would start with whatever goals they started with, reinforcement learning on specific examples would give them tiny islands of alignment to the goals we wanted, and they would end up broadly misaligned plus tiny islands of alignment that didn't matter. Evans et al implied that might not be true. If we trained them to be in favor of good things, then even though we could never teach them every single good thing, even a small handful would generalize into robustly loving the Good itself (presumably based on their pretraining-implanted concept of the Good as understood by humans). Despite it being very, very good, it wasn't perfect. AIs would still be rocked back and forth by any passing wind: a poor coding example here gives them a Hitler obsession, a reference to kittens there turns them good again. And at some point, a sufficiently intelligent and agentic AI could presumably pull itself together and get some consistent principles, which might not be ones we like. It was just one little ray of hope. https://www.astralcodexten.com/p/mysteries-of-ai-generalization

  • Wednesday · 1 hr 8 min

    Your Book Review: This Is Going To Hurt

    Finalist #9 in the Book Review Contest [This is one of the finalists in the 2026 book review contest, written by an ACX reader who will remain anonymous until after voting is done. I'll be posting about one of these a week for several months. When you've read them all, I'll ask you to vote for a favorite, so remember which ones you liked] (An adversarial book review) I. "Tuesday, 5 July 2005. Trying to work out a seventy-year-old lady's alcohol consumption to record in the notes. I've established that wine is her poison. Me: 'And how much wine do you drink per day, would you say?' Patient: 'About three bottles on a good day.' Me: 'OK . . . And on a bad day?' Patient: 'On a bad day I only manage one." A: The first faces I ever saw in this world were three sweaty, anxious obstetricians, and one of them was holding the rest of me. My father had been the senior surgeon on the Caesarean section. The patient on the table was my mother, who is also a gynaecologist. He was assisted by my paternal grandfather, who is also a gynaecologist. My maternal grandmother, who is also a gynaecologist, was outside in the corridor doing crowd control, partly because of her people skills and mostly because the operating theatre had run out of space for elbows. I was extracted from the uterus, given the customary slap on the rump, performed the customary screaming, and resolved on the spot, somewhere below the level of conscious memory, to give the speciality a hard pass. The first impression had been bad. I am, today, a psychiatry resident in the UK's National Health Service (NHS). I came to this through a sequence of choices that involved, at various points, an Indian medical internship, the discovery that I am fond of sleep and a predictable evening meal, and a gynaecology rotation that confirmed every prejudice the Caesarean had instilled. My family is very slightly disappointed. They are quite possibly correct. I tell you this not to establish my credentials as such, but because Adam Kay's This Is Going To Hurt is a book about obstetrics and gynaecology, alongside an unusually clearly documented decline in mental health, and reviewing it without naming where I'm reading it from would be a small dishonesty. The speciality is in my blood, more or less literally. The system Kay is describing is the one I currently work inside. The condition he is describing in himself, although he doesn't quite name it, is one I have seen up close in colleagues and, on at least one bad stretch, in myself. I will let my older, wiser, and possibly more handsome colleague take over: https://www.astralcodexten.com/p/your-book-review-this-is-going-to

  • Wednesday · 8 min

    AI Superforecasting Should Transform The FDA

    This is a guest post by ACX grantee Josh Morrison of 1DaySooner. AI superforecasters are coming. Within a few years, the average person will have the equivalent of a Nate Silver in their pocket, ready to predict whatever question they can think to ask it. Scott wrote: Savvy institutions will cede some of their strategic thinking to AI. Before starting a new project line, smart businesses will ask the superforecaster AIs how much money it will make (their investors will definitely be asking!) Smart political consultants will ask the superforecaster AIs about their candidates' chance of winning conditional on running this or that ad. The government isn't usually classified as a savvy institution, but we might hope that parts of it will seek AI forecaster advice. Probably defense analysts will include in their PowerPoint presentations some fact about how AI forecasters say their new fighter jet design is more likely to find a use case than some competing fighter jet design. I don't know anything about fighter jets, but I run an advocacy group that works on reforming clinical trials and the FDA, and I think cheap superforecasting could revolutionize our field. This is a guest post by ACX grantee Josh Morrison of 1DaySooner. AI superforecasters are coming. Within a few years, the average person will have the equivalent of a Nate Silver in their pocket, ready to predict whatever question they can think to ask it. Scott wrote: Savvy institutions will cede some of their strategic thinking to AI. Before starting a new project line, smart businesses will ask the superforecaster AIs how much money it will make (their investors will definitely be asking!) Smart political consultants will ask the superforecaster AIs about their candidates' chance of winning conditional on running this or that ad. The government isn't usually classified as a savvy institution, but we might hope that parts of it will seek AI forecaster advice. Probably defense analysts will include in their PowerPoint presentations some fact about how AI forecasters say their new fighter jet design is more likely to find a use case than some competing fighter jet design. I don't know anything about fighter jets, but I run an advocacy group that works on reforming clinical trials and the FDA, and I think cheap superforecasting could revolutionize our field. This is a guest post by ACX grantee Josh Morrison of 1DaySooner. AI superforecasters are coming. Within a few years, the average person will have the equivalent of a Nate Silver in their pocket, ready to predict whatever question they can think to ask it. Scott wrote: Savvy institutions will cede some of their strategic thinking to AI. Before starting a new project line, smart businesses will ask the superforecaster AIs how much money it will make (their investors will definitely be asking!) Smart political consultants will ask the superforecaster AIs about their candidates' chance of winning conditional on running this or that ad. The government isn't usually classified as a savvy institution, but we might hope that parts of it will seek AI forecaster advice. Probably defense analysts will include in their PowerPoint presentations some fact about how AI forecasters say their new fighter jet design is more likely to find a use case than some competing fighter jet design. I don't know anything about fighter jets, but I run an advocacy group that works on reforming clinical trials and the FDA, and I think cheap superforecasting could revolutionize our field. This is a guest post by ACX grantee Josh Morrison of 1DaySooner. AI superforecasters are coming. Within a few years, the average person will have the equivalent of a Nate Silver in their pocket, ready to predict whatever question they can think to ask it. Scott wrote: Savvy institutions will cede some of their strategic thinking to AI. Before starting a new project line, smart businesses will ask the superforecaster AIs how much money it will make (their investors will definitely be asking!) Smart political consultants will ask the superforecaster AIs about their candidates' chance of winning conditional on running this or that ad. The government isn't usually classified as a savvy institution, but we might hope that parts of it will seek AI forecaster advice. Probably defense analysts will include in their PowerPoint presentations some fact about how AI forecasters say their new fighter jet design is more likely to find a use case than some competing fighter jet design. I don't know anything about fighter jets, but I run an advocacy group that works on reforming clinical trials and the FDA, and I think cheap superforecasting could revolutionize our field. https://www.astralcodexten.com/p/ai-superforecasting-should-transform

  • Wednesday · 18 min

    King Ludd

    I. In the gods' great scramble for human followers, Nodens would seem to have lost decisively. We know him only from vague inscriptions at two archaeological sites near the Welsh-English border. One might have been his temple. He seems to have been a Romano-British-Celtic god of . . . hunting? rivers? . . . worshipped around the Severn estuary between 100 and 400 AD. His cult may have been dispersed by Christianity, or could have faded away before that, a victim of ordinary religious churn. Roman paganism was Schumpeterian; innovate or be destroyed. Nodens didn't innovate. Yet the more one looks, the less convinced one becomes that this is the whole story. Nodens was a river god; if you dam up a river in one spot, it will flow down other channels. Sometimes it will vanish underground, bursting out of some unexpected cavern miles away. Nodens was a hunter, and hunters know when to stay camouflaged. In 1929, an archaeologist digging at the Temple of Nodens had some questions about the etymology of the god's name, and asked Oxford to send a linguist. Oxford dispatched a young philology professor with an encyclopedic knowledge of European mythology, who spotted a connection that had evaded previous scholars: Nodens appeared to be the same figure as the Irish god-hero Nuada of the Silver Arm. Nuada was king of the Tuatha de Danaan, a race of immortals who sailed from the north on ships that were clouds and made war against the then-inhabitants of Ireland, the Fir Bolg. He fought bravely, wielding his all-powerful Sword of Light, but in the climax of the battle, the Fir Bolg champion cut off his right arm. This caused some temporary trouble (the laws of the time prevented a one-armed man from being king), but his people were skilled at magic and metalworking, so they made him a new arm of silver, hence his epithet. He ruled for some number of centuries, a golden age of crafting and wonder-working, until the Tuatha de Danaan were invaded in turn (this was a theme; our source for these stories is a medieval manuscript called The Book Of Invasions). The new invaders banished Nuada's people to the hills and forests, where they became the sidhe aka fae aka fairies. https://www.astralcodexten.com/p/king-ludd

  • Wednesday · 14 min

    Royce On San Francisco

    These are all excerpts from Josiah Royce's 1886 book, A History Of California From Conquest In 1846 To The Second Vigilance Committee In San Francisco: A Study Of American Character, which terminates in 1856. I've edited only to remove dates, mentions of historical sources, and a few sentences about gold mines. https://www.astralcodexten.com/p/royce-on-san-francisco

  • Wednesday · 35 min

    God Help Us, Let's Try To Learn About Mechanistic Interpretability Techniques

    The Story So Far Mechanistic interpretability is the science of "reading an AI's mind". Large language models are "grown, not built". Researchers run training data through a neural network. Eventually this creates a working AI; nobody really knows how. But a neural network is just a set of simulated neurons on a computer. The person with the computer can see the neurons, the connections between them, and which ones activate when the AI answers questions. So it seems like it should be possible to "reverse engineer" the AI. This would be scientifically useful: understand how AIs work, with possible relevance to human cognition. It could also be practically useful: find the circuits responsible for dishonesty, hallucination, bias, and other negative behaviors, then redesign those circuits. Unfortunately this is very hard. A modern AI has millions of neurons and trillions of connections between them (aka "parameters", "weights"). Their structure is apparently nonsensical: researchers started by seeking a 1:1 mapping between neurons and concepts, like a neuron that always fired when the AI was thinking about cats, but quickly learned that nothing like that existed. Their first big breakthrough came in 2023. Rather than a 1-to-1 neuron-to-concept mapping, they discovered a many-to-many mapping. Neurons 1 and 2 firing together might mean cat; 1 and 3 firing together might mean chair; 2 and 3 firing together might mean bread. Such mappings let AIs with "only" tens of thousands of neurons represent millions of concepts. There were far too many of these combinations for humans to map, but researchers set other, smaller AIs to mapping them and met with some early success - like this functional combination of neurons ("feature") representing "God" in an artificially-simple 512-neuron AI: https://www.astralcodexten.com/p/god-help-us-lets-try-to-learn-about.

  • October 5 · 55 min

    Your Book Review: The Tale Of Genji

    Finalist #8 in the Book Review Contest This is one of the finalists in the 2026 book review contest, written by an ACX reader who will remain anonymous until after voting is done. I'll be posting about one of these a week for several months. When you've read them all, I'll ask you to vote for a favorite, so remember which ones you liked] [Content warning: Sexual and relationship practices from a thousand years ago, from a time and place with a very different morality than what you probably subscribe to.] The past is an alien civilisation Around the year 1000, the Imperial Court of Japan in Kyoto was a world of opulence, aesthetics, and ambition. Isolated from the lives of regular commoners, every aspect of the lives of the elite were governed by complex etiquette rules, and relationships were thoroughly intertwined with politics and the ambition for power and wealth. High-ranking women and men lived lives so separate that they might have a passionate love affair without properly seeing each other's faces. It was in this world that Murasaki Shikibu, an intelligent and educated lady in Empress Shōshi's court, wrote The Tale of Genji, which is widely considered to be the world's oldest novel. It is an extraordinary masterpiece and a highly questionable soap opera, and I've never read anything like it. https://www.astralcodexten.com/p/your-book-review-the-tale-of-genji

  • October 5 · 28 min

    Absurd Adventure And Amygdalectomy Advocacy

    I am Daniel Böttger1. In 2023, my review of On The Marble Cliffs took second in the ACX book review contest, and Scott offered me the right to pitch him more essays. I have worked as a neuroscientist, so in 2024 I pitched a post with my theory of consciousness. Later that year, my connection to neuroscience took an unexpected turn, and I wrote about my experience getting diagnosed with brain cancer. This post is an update on how I'm doing. I'm doing well. Very well, in fact. Suspiciously well. So well that the only other person I've ever heard of doing as well as I am was Jo Cameron, who was profiled on ACX for her rare genetic mutation that makes her incapable of negative emotion. My case can't be a mutation, so it must be related to my brain cancer and subsequent surgery. I write about it here in the hopes of making a novel contribution to the study of low-suffering phenotypes. Content warning: the first part of this review contains medical details that some people might find gruesome; I am bad at judging these things since I can no longer feel disgust or fear myself, and have tried to err on the side of completeness. https://www.astralcodexten.com/p/absurd-adventure-and-amygdalectomy

  • October 5 · 31 min

    Nicholas Decker In Hell

    I. Econblogger Nicholas Decker is not a fan of AI 2040: One of the centerpieces of AI 2040 is the proposal that we pause the development of AI at a high level, use the AI to research alignment, and only then proceed. I am skeptical of this, and not only because it seems impractical to get such cooperation. My first argument is that I do not believe a period of "researching alignment" is meaningful – alignment research is simply capabilities research, patching particular bugs in the system, and we're not going to find anything deep without actually being in contact with the systems […] I envision AI alignment as being like research into aviation safety. There is no grand theory of why airplanes crash, unless you take that to mean gravity. Instead, we patch little problems. The airplane crashed because of metal fatigue in the engine – okay, we mandate inspections of engines, and prevent crashes from occurring by that source. As new problems arise, we iterate. We don't even need for there to be a crash to make improvements – we test proactively, we build in redundancy, and we monitor for deviations which could be a threat. What we are not doing is thinking about how we are going to keep flying saucers from crashing. If flying saucers are invented, then we will work to keep them from crashing, but we will use exactly the same methods. We will test them, see how they perform, and patch particular problems. AI will be the same way […] We should expect alignment to happen by default. My challenge for Nicholas is: would this work on you? https://www.astralcodexten.com/p/nicholas-decker-in-hell

  • October 5 · 37 min

    Your Book Review: Thomas Urquhart's Translation Of Rabelais

    Finalist #7 in the Book Review Contest [This is one of the finalists in the 2026 book review contest, written by an ACX reader who will remain anonymous until after voting is done. I'll be posting about one of these a week for several months. When you've read them all, I'll ask you to vote for a favorite, so remember which ones you liked] This is not a review of Rabelais. This is a review of a certain, incomplete translation of Rabelais. It is also arguably one of the greatest translations in our language. Let's meet the hero of our story. https://www.astralcodexten.com/p/your-book-review-thomas-urquharts

  • October 1 · 27 min

    Highlights From The Comments On The Substack Religion Debate

    [Original post: Why I'm Staying Out Of The Substack Religion Debate] Ben Smith writes: This post sure reads like participating in the object level debate, not just "writing a post about how I won't participate". I did joke about this at the end, but I also want to defend calling this a post about how I won't participate. This essay presented a kind of hand-wavey heuristic for why I'm not spending lots of time examining the details of every individual argument. This is fine, everyone has to do this or be overwhelmed, but I think it's important to keep hand-wavey heuristics for not participating in arguments, vs. actual participation in arguments, distinct. Little annoys me more than when I spend weeks carefully gathering citations and making a substantive contribution in a domain, and somebody responds with "well that's obviously all bullshit because it vaguely reminds me of something I have negative affect towards". It's not necessarily wrong to deprioritize a topic because it vaguely reminds you of something that you have negative affect toward, but I would prefer these people admit they're dismissing/ignoring it rather than claim to be engaging with it. I'm working on a longer post about this topic. https://www.astralcodexten.com/p/highlights-from-the-comments-on-the-491

  • October 1 · 1 hr 1 min

    Re: Re: Re: Pritchard On Liberal Happiness

    In early July, Cassie Pritchard argued on Twitter that liberalism had failed; it bet the farm on economic progress making people happier, but although it delivered impressive economic progress, happiness had failed to follow. In late July, I countered that Pritchard had made a mistake by comparing happiness to income, when the literature instead supports a correlation of happiness with log(income). Add the log term, and most happiness-income relationships reappear, and liberalism goes back to looking pretty good. Last week, Pritchard responded on her Substack. I don't have the interest to give this the full treatment it requires, but she deserves some response, so I'll make a few points. https://www.astralcodexten.com/p/re-re-re-pritchard-on-liberal-happiness

  • September 28 · 53 min

    Your Book Review: A Residence Of 21 Years In The Sandwich Islands

    [This is one of the finalists in the 2026 book review contest, written by an ACX reader who will remain anonymous until after voting is done. I'll be posting about one of these a week for several months. When you've read them all, I'll ask you to vote for a favorite, so remember which ones you liked] 1. A New Cause Area In October 1819, my grandmother's grandfather's grandfather, Hiram Bingham I, stood with his wife, Sybil, and his friends outside Park Street Church in Boston and bade farewell to family before venturing into the unknown. They would spend the next five months on a cramped ship sailing to a foreign land of strange people, full of "destitution, degradation, and barbarism." They did not know if they would ever return to America. Unlike others who voyaged out to sea, they were not whalers, nor merchants trying to make a quick profit. Instead, their goal was far more ambitious: to uplift an entire nation out of heathenry to civilization. Or as Hiram wrote, to "most effectually and most extensively promote the Redeemer's cause with the means that are put into our hands". I first came across Hiram's memoir, A Residence of Twenty-One Years in the Sandwich Islands, on my honeymoon to the Hawaiian Islands last summer. I had vague knowledge of a family connection to the area, and decided to do some research into it. As I started reading, I had a growing sense of deja vu as I recognized my own patterns of thinking in Hiram's words. Today's Effective Altruists sincerely want to do the most good possible, and often focus on international development as a means of improving lives. However, there is another group who fits that description equally well: 19th-century missionaries. Hiram and his colleagues believed that Heaven and Hell were not metaphorical, and that doing the most good meant saving the most souls from eternal torment. And what, they asked themselves, was the most effective means towards accomplishing this goal? Spreading the Gospel to those who had never heard it. All of humanity required salvation, and those who lived in foreign lands mattered just as much as those who lived nearby. As a missionary destination, the Hawaiian Islands (then known as the Sandwich Islands), had several compelling advantages. First, the islands were very neglected, being recently discovered. While not as important as China, Egypt/Palestine, or India, they still held a sizable population. And unlike those places, there was little competition from other missionaries or pre-existing organized religions, making them much more tractable for conversion. The mission to Hawaii would prove notably cost-effective compared to other missions1. Basically all that was needed was a ship, a printing press, and missionaries to teach the Bible. In other words, if the EA Forum existed in the early 19th century, I could easily imagine a post arguing that bringing the Gospel to the Sandwich Islands is a promising cause area. So, with the benefit of 200 years of hindsight, what can Effective Altruists and other aspiring do-gooders today learn from the previous wave of people who wanted to save the world? https://www.astralcodexten.com/p/your-book-review-a-residence-of-21

  • September 28 · 20 min

    Why I'm Staying Out Of The Substack Religion Debate

    I. Matthew Adelstein (aka Bentham's Bulldog) and Richard Chappell debate the existence of God. So do JP Andrew, Benjamin Tettu, Sangwon Lee, Ethan Muse, other Ethan, and "Atheistic Journals", all within this month! I thought the omnipresence of the early '00s online atheism debate was a time-bound historical phenomenon. But now that the blogosphere has reincarnated as Substack, it's back, nearly as strong as ever. I enjoyed participated in the early 00's version, but the current incarnation leaves me cold. I can't get as interested as I once did in the details of the Fine-Tuning Argument, the Argument From Miracles, et cetera. It's not just that I've already served my time in the theology mines. My lack of belief in God intuitively feels like it precedes all of these things. Consider by analogy a society where people regularly debated whether aliens assisted the rise of Napoleon. There are many reasons to believe in such assistance: Napoleon's rise from Corsican nobody to Emperor and would-be world conqueror was a bizarre deviation from the usual pattern of history. He won battles outnumbered 4-to-1, when everyone knows victory usually goes to the larger army. He became monarch of France immediately after it had declared eternal enmity against the concept of monarchy and resolved to murder anyone who didn't hate monarchy enough. And the arguments against such intervention are comparatively flimsy. True, nobody saw aliens, but a sufficiently advanced civilization could conduct its interventions in secret. True, our prior for alien intervention is generally low, but maybe this is unjustified: we have no idea how many historical events the aliens have intervened in; Alexander the Great was pretty strange too. True, Napoleon finally lost, but this is not decisive; maybe the aliens only wanted him to blaze brightly for a few years before his eventual defeat, or maybe stronger aliens were backing the Duke of Wellington. In a world where this hypothesis somehow entered the space of serious debate, it would be hard to dislodge. Our own historical community is protected from it not because they can precisely add up the Bayesian evidence for and against each of these considerations and conclude its falsehood, but because common sense precludes entertaining it in the first place. This isn't to say that Reason doesn't work - if someone could precisely add up the Bayesian evidence for and against these considerations, they would get the right answer - but as a historical matter, this type of delicate reasoning wasn't how our society resolved this question. My atheism is more deeply rooted in whatever prevented us from considering this question in the first place than in the type of delicate reasoning that could get us out of it. https://www.astralcodexten.com/p/why-im-staying-out-of-the-substack

  • September 28 · 59 min

    Your Book Review: The Escape Artist

    [This is one of the finalists in the 2026 book review contest, written by an ACX reader who will remain anonymous until after voting is done. I'll be posting about one of these a week for several months. When you've read them all, I'll ask you to vote for a favorite, so remember which ones you liked] Holocaust stories, both true and fictional, tend to repeat the same few clichés over and over. There's the innocent child who only partially understands what's happening (Diary of Anne Frank, Boy in the Striped Pajamas). There's the sentimental redemption story that focuses on a small individual act (Life is Beautiful, The Book Thief). And of course, there's the good German, or at least the morally conflicted one (Schindler's List, The Reader). You won't find any of these tropes in The Escape Artist. This 2022 book by Jonathan Freedland1 tells the true, and largely unknown, story of one of the few Jews ever to break out of Auschwitz. The details of his improbable escape are remarkable enough, but what really makes the story fascinating is the way it so thoroughly defies every single expectation we have of a Holocaust narrative. Its deeply unlikeable protagonist eventually alienates every friend and supporter he has, and dies a bitter old man, almost completely forgotten by history. His story lacks not only good Germans, but even good non-Germans, with his harshest criticism saved not for the Nazis, not even for the dithering Allies, but for the Jewish leaders of Europe. And though one could see the story of his escape as a triumph, in his own telling, it's a failure, for although he makes it out of Auschwitz against all odds, he fails at his larger mission: to stop the Holocaust. There's no redemption here, no moral uplift, no lessons save for perhaps the grimmest and most nihilistic "lesson" I've ever encountered in any story, Holocaust-related or otherwise: that when confronted with the unthinkable, most people's natural tendency is denial. But we're getting ahead of ourselves. To get out of Auschwitz, first you have to get into Auschwitz… https://www.astralcodexten.com/p/your-book-review-the-escape-artist

  • September 5 · 26 min

    The Quest For Caffeine You Can Have At Night

    Since the beginning of time, mankind has yearned to drink a cup of coffee at 5 PM and go to sleep at 10. But now there's an entire scientific subfield and several companies pandering to this absurd fantasy. Here's a simplified diagram of caffeine metabolism: Caffeine is converted to a different stimulating chemical called paraxanthine by a liver enzyme called CYP1A2, over a half-life of ~5 hours. Then the same enzyme converts paraxanthine into other non-stimulating chemicals that don't matter, over a half-life of about three hours. Kman on Less Wrong has graphed the total effective concentration over time: Over the course of hours, the liver converts caffeine into paraxanthine. These are (by assumption) equally potent, so total effective concentration (the dashed red line) goes down slowly. (Why does it go down at all? Because of the simplification in the diagram above: only about 80% of caffeine is converted to paraxanthine; the rest is converted to other, less active metabolites.) By hour ten, paraxanthine predominates, the liver is mostly converting paraxanthine to other non-stimulating chemicals, and effective concentration continues to decrease. In this model, we see that the effective half-life of caffeine is close to ten hours1! What if we want it to be less? There are three levers we can pull: the enzyme, the metabolite, and the starting chemical. https://www.astralcodexten.com/p/the-quest-for-caffeine-you-can-have

  • September 5 · 21 min

    The Foothills Of Bay Area House Party

    [previously in series: 1, 2, 3, 4, 5, 6, 7, 8, 9] Paul Graham once said that every city sends a message. New York says you should make more money. Berkeley says you should live better. Boston says you should be smarter. People shouldn't decide on a permanent residence until they've lived in several cities and understand their differing psychological effects. San Francisco sends a message too. It speaks it in a cacophony of dissonant voices, some sounding like the hissing of snakes, others like the chittering of insects. "You should pierce the veil," it says, with a faint accent which you are not scholarly enough to recognize as ancient Sumerian. "You should rip through the flimsy screen that separates your world from the infinite, and witness what lies behind. Because you'd like what you saw there? Oh no, nothing like that. But aren't you curious? The thirst for knowledge that moved Eve, Faust, Pandora - don't you have it too?" There's also a second message from a second voice, one which sounds like a deranged carnival barker, constantly shouting "STONKS! STONKS! STONKS! STONKS!" Which of the two voices you hear depends on your personality, and maybe how many psychedelics you took in college. According to legend, Sam Altman hears both voices simultaneously all the time, like those Tibetan throat singers who can harmonize with themselves. But when the demonic babble becomes too much to tolerate, the San Franciscans drown it out with alcohol, loud music, and various forms of tedious socialization. Thus the famous Bay Area house parties, one of which you will be attending this very night. https://www.astralcodexten.com/p/the-foothills-of-bay-area-house-party

  • September 5 · 6 min

    MacGregor The Bridge Builder

    Old Scottish joke: A man at the bar is complaining: "You see that bridge there? I built it with my own hands! But do they call me 'MacGregor The Bridge-Builder'? No! And I raised five beautiful children! But do they call me 'MacGregor The Child-Raiser'? No! But, you fuck one sheep . . ." Has MacGregor been treated unfairly? https://www.astralcodexten.com/p/macgregor-the-bridge-builder

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