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Artwork for Young Urban Anesthesiologists
Young Urban Anesthesiologists · Friday · 1 hr 13 min

Der Kaffee, das Bewusstsein und die Narkose

Warum wir das Licht so plötzlich ausschalten Primärquelle: Zhou DW, Mowrey DD, Tang P, Xu Y. (2015). Percolation Model of Sensory Transmission and Loss of Consciousness Under General Anesthesia. Physical Review Letters 115, 108103. DOI: 10.1103/PhysRevLett.115.108103 Methodische Grundlagen: Bollobás B, Riordan O. (2006). Percolation. Cambridge University Press. Watts DJ, Strogatz SH. (1998). Collective dynamics of 'small-world' networks. Nature 393, 440. Kullback S, Leibler RA. (1951). On Information and Sufficiency. Ann Math Stat 22, 79. Netzwerkarchitektur: Markov NT et al. (2013). Cortical high-density counterstream architectures. Science 342, 1238406. Felleman DJ, Van Essen DC. (1991). Distributed hierarchical processing in the primate cerebral cortex. Cereb Cortex 1, 1. Sporns O et al. (2004). Organization, development and function of complex brain networks. Trends Cognit Sci 8, 418. Narkose, EEG & Bewusstsein: Brown EN, Purdon PL, Van Dort CJ. (2011). General anesthesia and altered states of arousal: a systems neuroscience analysis. Annu Rev Neurosci 34, 601. Steyn-Ross ML et al. (2001). Toward a theory of the general-anesthetic-induced phase transition of the cerebral cortex. I & II. Phys Rev E 64, 011917 / 011918. Ching S et al. (2010). Thalamocortical model for a propofol-induced α-rhythm associated with loss of consciousness. PNAS 107, 22665. Ching S et al. (2012). A neurophysiological–metabolic model for burst suppression. PNAS 109, 3095. Feshchenko VA, Veselis RA, Reinsel RA. (2004). Propofol-induced alpha rhythm. Neuropsychobiology 50, 257. Tinker JH, Sharbrough FW, Michenfelder JD. (1977). Anterior shift of the dominant EEG rhythm during anesthesia in the Java monkey. Anesthesiology 46, 252. Lee U et al. (2009). The directionality and functional organization of frontoparietal connectivity during consciousness and anesthesia in humans. Conscious Cogn 18, 1069. Supp GG et al. (2011). Cortical hypersynchrony predicts breakdown of sensory processing during loss of consciousness. Curr Biol 21, 1988. Bewusstseinstheorie & Messung: Tononi G. (2008). Consciousness as integrated information: a provisional manifesto. Biol Bull 215, 216. Casali AG et al. (2013). A theoretically based index of consciousness independent of sensory processing and behavior. Sci Transl Med 5, 198ra105. Klinisch relevante Anschlussarbeiten: Samuelsson AR, Brandon NR, Tang P, Xu Y. (2014). Cellular registration without behavioral recall of olfactory sensory input under general anesthesia. Anesthesiology 120, 890. Borjigin J et al. (2013). Surge of neurophysiological coherence and connectivity in the dying brain. PNAS 110, 14432. Fuentealba P, Steriade M. (2005). The reticular nucleus revisited: intrinsic and network properties of a thalamic pacemaker. Prog Neurobiol 75, 125. Serienbezug: Young Urban Anesthesiologists — Orch-OR-Folge (Hameroff & Penrose): dieselbe Frage, entgegengesetzte Richtung (nach unten in die Zelle statt nach oben ins Netzwerk). hier gehts zum Feedback und EFN-Formular Achtung: Fortbildungspunkte können nur innerhalb von 4 Wochen nach Veröffentlichung der Episode beantragt werden. Eine nachträgliche Meldung ist bei der Ärztekammer leider nicht möglich.

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Warum wir das Licht so plötzlich ausschalten

Primärquelle:

  • Zhou DW, Mowrey DD, Tang P, Xu Y. (2015). Percolation Model of Sensory Transmission and Loss of Consciousness Under General Anesthesia. Physical Review Letters 115, 108103. DOI: 10.1103/PhysRevLett.115.108103

Methodische Grundlagen:

  • Bollobás B, Riordan O. (2006). Percolation. Cambridge University Press.
  • Watts DJ, Strogatz SH. (1998). Collective dynamics of 'small-world' networks. Nature 393, 440.
  • Kullback S, Leibler RA. (1951). On Information and Sufficiency. Ann Math Stat 22, 79.

Netzwerkarchitektur:

  • Markov NT et al. (2013). Cortical high-density counterstream architectures. Science 342, 1238406.
  • Felleman DJ, Van Essen DC. (1991). Distributed hierarchical processing in the primate cerebral cortex. Cereb Cortex 1, 1.
  • Sporns O et al. (2004). Organization, development and function of complex brain networks. Trends Cognit Sci 8, 418.

Narkose, EEG & Bewusstsein:

  • Brown EN, Purdon PL, Van Dort CJ. (2011). General anesthesia and altered states of arousal: a systems neuroscience analysis. Annu Rev Neurosci 34, 601.
  • Steyn-Ross ML et al. (2001). Toward a theory of the general-anesthetic-induced phase transition of the cerebral cortex. I & II. Phys Rev E 64, 011917 / 011918.
  • Ching S et al. (2010). Thalamocortical model for a propofol-induced α-rhythm associated with loss of consciousness. PNAS 107, 22665.
  • Ching S et al. (2012). A neurophysiological–metabolic model for burst suppression. PNAS 109, 3095.
  • Feshchenko VA, Veselis RA, Reinsel RA. (2004). Propofol-induced alpha rhythm. Neuropsychobiology 50, 257.
  • Tinker JH, Sharbrough FW, Michenfelder JD. (1977). Anterior shift of the dominant EEG rhythm during anesthesia in the Java monkey. Anesthesiology 46, 252.
  • Lee U et al. (2009). The directionality and functional organization of frontoparietal connectivity during consciousness and anesthesia in humans. Conscious Cogn 18, 1069.
  • Supp GG et al. (2011). Cortical hypersynchrony predicts breakdown of sensory processing during loss of consciousness. Curr Biol 21, 1988.

Bewusstseinstheorie & Messung:

  • Tononi G. (2008). Consciousness as integrated information: a provisional manifesto. Biol Bull 215, 216.
  • Casali AG et al. (2013). A theoretically based index of consciousness independent of sensory processing and behavior. Sci Transl Med 5, 198ra105.

Klinisch relevante Anschlussarbeiten:

  • Samuelsson AR, Brandon NR, Tang P, Xu Y. (2014). Cellular registration without behavioral recall of olfactory sensory input under general anesthesia. Anesthesiology 120, 890.
  • Borjigin J et al. (2013). Surge of neurophysiological coherence and connectivity in the dying brain. PNAS 110, 14432.
  • Fuentealba P, Steriade M. (2005). The reticular nucleus revisited: intrinsic and network properties of a thalamic pacemaker. Prog Neurobiol 75, 125.

Serienbezug:

  • Young Urban Anesthesiologists — Orch-OR-Folge (Hameroff & Penrose): dieselbe Frage, entgegengesetzte Richtung (nach unten in die Zelle statt nach oben ins Netzwerk).

hier gehts zum Feedback und EFN-Formular

Achtung: Fortbildungspunkte können nur innerhalb von 4 Wochen nach Veröffentlichung der Episode beantragt werden. Eine nachträgliche Meldung ist bei der Ärztekammer leider nicht möglich.

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