What's the deal with cortisol?

This week, Emily and Perry take on cortisol, the much-maligned stress hormone blamed for heart attacks and stubborn belly fat. But how much heat should cortisol really be getting? How do you know when yours is too high? Too low? Is it ever really worth measuring? And you guys, what did Mendelian randomization ever do to Emily?! Plus: the FDA signs off on ZYN pouches, explosive diarrhea in the Midwest, and apparently GLP-1s are really, really easy to get. Submit a question for our weekly mailbag at wellnessactually.fm. See omnystudio.com/listener for privacy information.