0:00-1:46:15
Streams straight from the publisher. podnod never proxies or re-hosts episode audio.
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler
The Masters of the ScienTWIVic Universe discuss a novel poxvirus isolate from an immunosuppressed patient, H1N1 and the gain-of-function debate, and attenuation of dengue virus by recoding the genome.
Links for this episode- Paula Pitha-Rowe (Balt Sun)
- Novel poxvirus (CID)
- H1N1 and gain-of-function debate (mBio)
- Recoding dengue virus genome (PNAS)
- Attenuation by dinucleotide frequency change (PNAS)
- Codon pair and dinucleotide bias not distinguished (PNAS)
- Codon pair deoptimization artefact of CG/UA change (eLife)
- Can engineering subdue viral vaccine reversion? (Virus Evol)
- Attenuation by a thousand cuts (NEJM)
- Image credit
- Letters read on TWiV 351
Alan - Genetic roulette Rich - The Huntington Kathy - Simulated vomiting machine (video) Dickson - Last Cassini Saturn flybyVincent - Decaying Still Life (YouTube)
Listener Pick of the WeekKen - Cave meterology (Times, Nature)
Send your virology questions and comments to twiv@twiv.tv
Vincent Racaniello
en.wikipedia.orgDickson Despommier
verticalfarm.comAlan Dove
turbidplaque.comRich Condit
mgm.ufl.eduKathy Spindler
sitemaker.umich.eduPaula Pitha-Rowe
baltimoresun.compoxvirus
ncbi.nlm.nih.govgain-of-function
mbio.asm.orgRecoding
pnas.orgdinucleotide frequency change
pnas.orgnot distinguished
pnas.orgdeoptimization
ncbi.nlm.nih.govsubdue
ve.oxfordjournals.orgthousand cuts
nejm.orgImage credit
commons.wikimedia.orgLetters read
twiv.tvGenetic roulette
twitter.comThe Huntington
huntington.orgvomiting machine
journals.plos.orgvideo
youtu.beLast Cassini Saturn flyby
nasa.govDecaying Still Life
youtu.beTimes
nytimes.comNature
nature.com