This Week in Microbiology
184: CRISPR-Cas immune systems
Sep 7, 2018 · 1 hr 26 min · Episode 184 · 41.4 MB
0:00-1:26:09
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Sam Sternberg discusses his work on exploring and exploiting CRISPR-Cas immune systems, beginning as a graduate student with Jennifer Doudna, at a biotech start-up, and in his laboratory at Columbia University.
Host: Vincent Racaniello
Guest: Sam Sternberg
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Links for this episode- Sternberg Laboratory at Columbia
- Mechanism of substrate selection by Cas9 (RNA)
- DNA interrogation by Cas9 (Nature)
- Conformational control of DNA target cleavage by Cas9 (Nature)
- A Crack in Creation by Doudna and Sternberg
- What if we could rewrite the human genome? (YouTube)
- Sam Sternberg
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
Send your microbiology questions and comments to twim@microbe.tv
Vincent Racaniello
virology.wsSam Sternberg
sternberglab.orgPatron of TWiM
patreon.comsubstrate selection
ncbi.nlm.nih.govDNA interrogation
ncbi.nlm.nih.govDNA target cleavage
ncbi.nlm.nih.govA Crack in Creation
amzn.torewrite the human genome?
youtu.beSam Sternberg
shsternberg.comRonald Jenkees
ronaldjenkees.com