GLP-1 News Update: Stopping the Meds, What Happens Next & The Future of New Treatments

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In this episode of The Plus SideZ, we break down the latest GLP-1 news and what it actually means in real life.

We’re joined by Dave (Man on Mounjaro), who shares his firsthand experience coming off a GLP-1 after years on treatment, while we also unpack emerging research and what’s coming next in this space.

This conversation covers both data and lived experience, including:

• What new studies say about stopping GLP-1 medications
 • Why benefits may reverse after discontinuation
 • Real-world weight regain, hunger, and metabolic changes
 • Mental health and brain-related effects tied to these medications
 • The difference between GLP-1 and GIP and why it matters
 • New and emerging medications being studied for neurological and metabolic conditions
 • Where treatment may be headed next beyond weight loss

This episode connects the dots between science, patient experience, and the future of obesity treatment so you can better understand what’s happening now and what may be coming next.

Whether you’re on a GLP-1, considering one, or thinking about long-term use, this is a must-listen conversation.

Guest Host:  Dave Knapp @OnThePenPodcast

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