The Pharma Perspective

Mirko von Hein

The Pharma Perspective brings you clear, insightful conversations on the ideas, challenges, and innovations shaping the pharmaceutical industry.

From health economics and market access to clinical evidence and policy, this podcast explores the perspectives that matter for anyone working in or around pharma.

Whether you're a consultant, researcher, or industry professional, you'll gain practical insights and a deeper understanding of how the pieces of the pharma world fit together.

Hosted by Mirko von Hein, The Pharma Perspective cuts through complexity and shares viewpoints that help you stay informed, think critically, and succeed in the world of pharma.

LinkedIn: https://www.linkedin.com/in/mirkovonhein/
YouTube: https://www.youtube.com/@MirkovonHein
Instagram: https://www.instagram.com/mirkovonhein

Subscribe Listen in podnod RSS feed Show website

8 episodes
Updated July 27

Episodes8

Newest first

July 27 · 1 hr 16 min
Most Favored Nation Pricing, Tariffs & the Rise of China | Neil Grubert | EP 8
Most Favored Nation (MFN) drug pricing, pharma tariffs, and China overtaking the US in new drug launches: on this episode of The Pharma Perspective, market access and policy expert Neil Grubert breaks down the forces reshaping how the world prices and pays for medicines. Neil explains what Trump's Executive Order on Most Favored Nation pricing really means, why the US funds an estimated 75% of global pharmaceutical profits, and how tariffs are being used to pressure drug companies and governments. He also unpacks the EU Pharmaceutical Package, Europe's growing launch hesitancy, and the moment when China overtook the US in new medicines brought to market, before closing on what he would change about global drug pricing. Essential viewing for anyone in pharma, market access, HEOR, health policy, or life sciences.
April 14 · 1 hr 8 min
Pharma's Worst Job Market in 30 Years: Top Recruiter Reveals What to Do Now | Grant Coren | EP 7
In this episode of The Pharma Perspective podcast, Grant Coren, life science recruiter with over 30 years of experience and founder of his own executive search practice, discusses the state of the pharma job market in 2026, why hiring has slowed across pharma, biotech, and CRO alike, how AI screening tools and applicant tracking systems are changing — and distorting — the recruitment process, why most CVs fail to differentiate candidates and what to do instead, the ethical problems with how many recruiters operate and how job seekers should navigate that, the difference between retained executive search and contingency recruitment, how indirect referencing allows recruiters to vet candidates outside of formal references, why loyalty is no longer rewarded in pharma careers and when job-hopping actually accelerates progression, the personality traits that predict success in different pharma roles, the real impact of ageism in life sciences hiring, and why getting your first job in the industry remains the hardest step of all.
January 15 · 1 hr 5 min
Rethinking Medications: From Academic Detailing to Broken Drug Regulation | Jerry Avorn | EP 6
In this episode of The Pharma Perspective podcast, Jerry Avorn, Professor of Medicine at Harvard Medical School and author of "Rethinking Medications," discusses the state of drug regulation in the United States, the problems with accelerated approvals and missing confirmatory trials, how academic detailing can change prescribing behavior more effectively than guidelines, the misuse of surrogate endpoints in drug development, why weak FDA enforcement actually harms pharmaceutical innovation, the absence of cost-effectiveness analysis and health technology assessment in US drug policy, and where he sees hope for reform through state-level drug policy coalitions and evidence-based prescribing initiatives.
January 15 · 1 hr 15 min
Measuring What Patients Actually Care About | Katja Rüdell | EP 5
In this episode of The Pharma Perspective podcast, Katja Rüdell, one of the world's leading clinical outcome assessment and patient-reported outcomes experts, discusses the role of PROs in drug development, regulatory expectations from FDA and EMA for outcome measure validation, the challenges of developing fit-for-purpose COA instruments, the evolution of patient-centred research in pharmaceutical clinical trials, and best practices for ensuring PRO data meets both regulatory and clinical standards.
Dec 7, 2025 · 37 min
What Does the ABPI Actually Do? | Jack Neill-Hall | EP 4
In this episode of The Pharma Perspective podcast, Jack Neill-Hall from the Association of the British Pharmaceutical Industry (ABPI) discusses the UK pharmaceutical pricing environment, NICE's cost-effectiveness threshold and appraisal process for NHS medicines, industry transparency through the Code of Practice and Disclosure UK, healthcare budget allocation, and why some medicines never reach UK assessment.
Dec 7, 2025 · 53 min
Is Raising the NICE Threshold Bad for NHS Patients? | Karl Claxton | EP 3
In this episode of "The Pharma Perspective", I speak with Karl Claxton, Professor of Economics at the University of York and founding NICE Appraisal Committee member, about his open letter to the UK Prime Minister on pharmaceutical pricing for branded medicines, why raising the NICE willingness-to-pay threshold would be catastrophic for NHS patients, and his proposals for fundamentally reforming health technology assessment and how we value pharmaceutical innovation. 💷🏥
Oct 28, 2025 · 1 hr 11 min
Starting a Pharma Consultancy in a Pandemic: The PharmacoEvidence Story | Barinder Singh | EP 2
Join me in my discussion with Barinder Singh, Founder of PharmacoEvidence, who quit his stable HEOR job in 2020—amid a pandemic and with a baby on the way—to start his own consultancy. In this episode of The Pharma Perspective, we explore how that bold decision turned into a thriving 40+ person company leading NICE submissions with AI-validated methods. We also talk about what it really takes to build an HEOR consultancy, the subjectivity in NICE appraisals, and how AI is reshaping evidence synthesis. A conversation about timing, risk, and self-awareness you won't want to miss.
Aug 17, 2025 · 50 min
How to Build a Meaningful Pharma Career – Leadership Lessons from a GM | Peter Wickersham | EP 1
Join me in my discussion with Peter Wickersham, Pharma Vice President & General Manager with 25+ years of experience, as we explore leadership, career growth, and navigating the evolving pharma industry in the age of AI. In this episode of Pharma Perspectives, Peter shares his insights on the challenges and opportunities shaping pharma today, offering practical advice for professionals interested in health economics, strategy, and the future of healthcare. Whether you're a healthcare professional, consultant, or simply curious about how the pharma world works behind the scenes, this conversation is packed with actionable insights and thought-provoking ideas.