Can AI Help Cure Genetic Disease?

Corey and Grant sit down with Mammoth Biosciences co-founder and CEO Dr. Trevor Martin to explain how CRISPR is moving from a laboratory tool toward one-time medicines. Trevor breaks down how Mammoth searches massive biological datasets for new CRISPR systems, why AI is useful but still constrained by missing clinical data, and what it would take to build a feedback loop between AI models, wet labs, and human trials. The conversation also covers personalized medicine, the economics of one-time cures, organoids, and why a medical breakthrough may be the clearest way for AI to prove its value to the public. Mammoth Biosciences - https://mammoth.bio Subscribe to The Neuron newsletter: https://theneuron.ai Sponsored by Mercor: Check out the AI Productivity Index (APEX) here: https://www.mercor.com/apex/?utm_source=neuron&utm_medium=podcast&utm_campaign=apex&utm_content=10_7 Sponsored by Outshift:“Scaling Out Superintelligence” Vijoy Pandey, January 2026. The technical whitepaper detailing the Internet of Cognition architecture, three-layer stack, and cognition state protocols. https://outshift.cisco.com/internet-of-cognition/whitepaper?utm_campaign=fy27q1_outshift_ww_paid_ioc-neuron-wp_podcast&utm_channel=podcast&utm_source=podcast Internet of Cognition Interactive Demo Clickable walkthrough showing per-agent activity, intent, context, and collective reasoning across a multi-agent SRE system.https://outshift.cisco.com/internet-of-cognition/explore?utm_campaign=fy27q1_outshift_ww_paid_ioc-neuron-explore_podcast&utm_channel=podcast&utm_source=podcast