
The DUTCH Podcast
Test Before You Prescribe: A Low Testosterone Case Study Review
April 7 · 51 min · Episode 148 · 37.4 MB
0:00-51:58
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In this episode, Dr. Jaclyn Smeaton and DUTCH Founder Mark Newman discuss a case study published in Integrative Medicine: A Clinician’s Journal in which Mark himself was the patient. The case covers the step-by-step hormonal and metabolic effects of using HCG to boost endogenous testosterone, revealing how increasing testosterone can cascade into elevated estrogen, impaired estrogen clearance, and strained methylation capacity.
Their conversation also highlights:
- The benefits of combining serum testing and DUTCH testing to monitor dosing as well as metabolism, clearance, and methylation
- How methylation is affected by raising testosterone
- The value of tracking step-by-step supplementation plans with repeated testing
- The importance of baseline testing before beginning testosterone therapy
- An upcoming research publication that compares hormone testing methods for testosterone monitoring
Read the DUTCH article and access the full IMCJ case report.
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- 0:35Episode Introduction
- 1:52Introduction to the Case Study
- 3:16Testosterone Monitoring and DUTCH Testing
- 4:54Understanding Testosterone Levels in Men
- 8:17Interventions for Increasing Testosterone
- 12:12The Impact of Estrogen on Testosterone Therapy
- 13:22Strategies for Managing Estrogen Levels
- 14:45Improving Estrogen Clearance and Methylation
- 19:22The Role of Trimethylglycine in Methylation
- 23:37Become A DUTCH Provider
- 26:19Case Study Conclusion and Clinical Implications
- 28:18Understanding Stress Responses and Biochemistry
- 29:43Testing and Monitoring Hormone Therapy
- 35:59Testosterone Therapy in Women
- 39:25The Role of Serum vs. Saliva Testing
- 44:14Evaluating Evidence in Hormone Therapy
- 47:35The Importance of Scientific Integrity