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The Beyond Tomorrow Podcast with Julian Issa · Thursday · 55 min

Longevity Scientist: Could THIS be the Missing Key to Healthy Aging?

What if the key to aging better is taking care of your body's batteries? For 20% off all Timeline products, go to timeline.com/beyondtomorrow Dr. Singh explains why mitochondrial health is becoming a major focus in longevity science. He unpacks the research behind urolithin A, how it supports cellular renewal, and why supplements should never replace the basics. The conversation covers the habits that matter most, from exercise and sleep to fasting and gut health. They also explore how to separate real science from longevity hype. Finally, they look ahead to the future of healthy aging, where better diagnostics, AI, and preventive medicine could help us stay healthier for longer, not just live longer. Dr. Singh is the Chief Medical Officer at Timeline and a physician-scientist specializing in immunology, mitochondrial health, and longevity. His research focuses on translating cutting-edge science into evidence-based interventions that help people age healthier. What You’ll Learn Why mitochondrial health matters for longevity How urolithin A supports healthy aging The habits that have the strongest evidence How to spot longevity hype Where longevity science is headed next ⏱ Timestamps 00:00 Intro 00:14 Why Urolithin A Matters 02:20 The Best Ways to Boost Mitochondria 03:20 Can We Reverse Aging? 06:37 Why Your Immune System Ages First 08:20 Targeting the Hallmarks of Aging 10:53 Fifteen Years, One Mission 12:24 The Search for a Longevity Superfood 15:26 Do You Really Need Supplements? 17:58 Three Ways to Improve Mitochondrial Health 20:02 Creatine + Urolithin A Explained 21:41 What Early Users Reported 24:13 Where Skincare Meets Longevity 25:42 Why Longevity Takes Time 28:15 The Three Pillars of Healthy Aging 30:01 The Shift to Preventive Medicine 31:50 Why Mitochondria Are Going Mainstream 34:35 Mitophagy vs. Autophagy 35:38 How Antibiotics Affect Aging 37:49 Rebuilding Your Gut Microbiome 39:59 Prebiotics vs. Probiotics vs. Postbiotics 42:11 The Most Underrated Longevity Habit 43:30 The Gut-Brain Connection 45:04 Melatonin and Mitochondrial Health 45:58 The Biggest Longevity Myth 46:35 Why Metabolic Health Matters 48:19 When GLP-1 Drugs Make Sense 49:32 The Hidden Downsides of GLP-1s 51:12 What Centenarians Can Teach Us 52:48 Mitochondrial Health in 2031 54:17 If Tomorrow Is Your Last Day... Connect with Dr. Singh Website: https://www.timeline.com/ Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ Instagram: https://www.instagram.com/juliankissa/ LinkedIn: https://uk.linkedin.com/in/julian-issa Website: www.beyondtomorrowpodcast.com Email: bookings@beyondtomorrowpodcast.com Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

0:00-55:47

transcript

No transcript — this publisher did not publish one.

show notes

What if the key to aging better is taking care of your body's batteries?

For 20% off all Timeline products, go to timeline.com/beyondtomorrow

Dr. Singh explains why mitochondrial health is becoming a major focus in longevity science. He unpacks the research behind urolithin A, how it supports cellular renewal, and why supplements should never replace the basics.

The conversation covers the habits that matter most, from exercise and sleep to fasting and gut health. They also explore how to separate real science from longevity hype.

Finally, they look ahead to the future of healthy aging, where better diagnostics, AI, and preventive medicine could help us stay healthier for longer, not just live longer.

Dr. Singh is the Chief Medical Officer at Timeline and a physician-scientist specializing in immunology, mitochondrial health, and longevity. His research focuses on translating cutting-edge science into evidence-based interventions that help people age healthier.

What You’ll Learn

  • Why mitochondrial health matters for longevity

  • How urolithin A supports healthy aging

  • The habits that have the strongest evidence

  • How to spot longevity hype

  • Where longevity science is headed next

⏱ Timestamps

00:00 Intro

00:14 Why Urolithin A Matters

02:20 The Best Ways to Boost Mitochondria

03:20 Can We Reverse Aging?

06:37 Why Your Immune System Ages First

08:20 Targeting the Hallmarks of Aging

10:53 Fifteen Years, One Mission

12:24 The Search for a Longevity Superfood

15:26 Do You Really Need Supplements?

17:58 Three Ways to Improve Mitochondrial Health

20:02 Creatine + Urolithin A Explained

21:41 What Early Users Reported

24:13 Where Skincare Meets Longevity

25:42 Why Longevity Takes Time

28:15 The Three Pillars of Healthy Aging

30:01 The Shift to Preventive Medicine

31:50 Why Mitochondria Are Going Mainstream

34:35 Mitophagy vs. Autophagy

35:38 How Antibiotics Affect Aging

37:49 Rebuilding Your Gut Microbiome

39:59 Prebiotics vs. Probiotics vs. Postbiotics

42:11 The Most Underrated Longevity Habit

43:30 The Gut-Brain Connection

45:04 Melatonin and Mitochondrial Health

45:58 The Biggest Longevity Myth

46:35 Why Metabolic Health Matters

48:19 When GLP-1 Drugs Make Sense

49:32 The Hidden Downsides of GLP-1s

51:12 What Centenarians Can Teach Us

52:48 Mitochondrial Health in 2031

54:17 If Tomorrow Is Your Last Day...


Connect with Dr. Singh

Website: https://www.timeline.com/ 

Connect with Julian

Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/  

Instagram: https://www.instagram.com/juliankissa/  

LinkedIn: https://uk.linkedin.com/in/julian-issa  

Website: www.beyondtomorrowpodcast.com 

Email: bookings@beyondtomorrowpodcast.com 

Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

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