The Full Picture On UTIs
transcript
show notes
🎙️ More than half of women will have a UTI by age 32, and up to 4 in 10 will have another within six months. Yet the entire public conversation around prevention is built on cranberry marketing, wiping myths, and supplement brands. This episode rebuilds the picture from the ground up, using the 2025 AUA/CUA/SUFU guideline reordering.
🧬 We break down the real physiology: your bladder isn't sterile, E. coli doesn't just "splash around" but hooks into the bladder wall, and why women are up to 30x more susceptible than men. Plus the evidence hierarchy and where D-mannose and cranberry juice actually land (spoiler: not where wellness influencers say).
⚡ Why methenamine hippurate (a drug most people have never heard of) was shown to be as effective as long-term antibiotics without the resistance risk.
🩺 We also cover the antibiotic resistance cycle, the chronic UTI controversy and why some women's symptoms fall through the cracks, and the massively under-investigated role of pelvic floor dysfunction in recurrent infections.
All references are in the full UTI article available on my Substack and Patreon.
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