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Peptide of The Week · August 6 · 1 hr 2 min

Peptide Q&A #53 – TRT for Low T, Pituitary Tumor Cautions & Peptide Timing on Retatrutide

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk. Welcome back, warriors! Will's back from Italy engaged! In this week's Peptide Q&A, JD Denham and William T. Haas cover what peptides to stop before blood work, how to sequence a cellular rebuild stack, Tesamorelin timing on Retatrutide, TRT for a truck driver with total T of 396, and why a pituitary tumor changes everything. Chapters: 00:00 – Intro & Welcome Back 00:40 – The Proposal Story 07:00 – Upcoming Weekend Retreat Announcement 09:00 – Big Guests Coming to the Podcast 11:39 – Q&A: Peptides to Stop Before Blood Work 13:28 – Q&A: Cellular Rebuild Stack & Sequencing 23:22 – Q&A: Sermorelin & Ipamorelin Dosing 29:49 – Q&A: BPC-157 Sublingual vs Oral 32:26 – Q&A: Reconstituted Reta Shelf Life 36:36 – Q&A: TRT Protocol for Low Testosterone 43:14 – Q&A: Timing Tesa/Ipa with Reta 48:25 – Q&A: Combining Multiple Peptides in One Injection 49:20 – Q&A: HGH vs CJC/Ipa Timing with GLP-1 50:36 – Q&A: Muscle Growth Peptides with Pituitary History 53:19 – Prague Trip Recap 59:54 – Outro & Feedback Request We cover: • What to Stop Before Blood Work: Why secretagogues, MK-677, HCG, Kisspeptin and biotin can all skew your labs and how long to stop each before testing • Cellular Rebuild Stack all at Once or Sequenced?: Why Fox04 first clears the trash, why SS-31 must come before MOTS-C, and why throwing the kitchen sink in at once defeats the purpose • Epithalon Dosing Explained: Why 100 migs twice a year is the standard, why 10 migs for 10 days and 5 migs for 20 days are both correct, and why Paul Bakhtiar starts everyone here • Sermorelin + Ipamorelin at 260 Down to 238 should You Up the Dose?: Why a caloric deficit blunts IGF-1 response, why winning streaks aren't the time to add more, and how to use plateau busters instead • BPC-157 Sublingual vs Oral for Gut Health: Why BPC was born in gastric juices and why oral capsules beat sublingual for gut-specific use every time • How Long Can You Keep a Reconstituted Retatrutide Vial: Why 28 days is the bacteriostatic water standard not a cliff edge and why buying the right vial size solves the problem • TRT Protocol for a Truck Driver with Total T of 396: Why high body fat raises estrogen and SHBG, why 180-200 migs of test twice weekly is the starting point, and why life changes in three weeks • Tesamorelin + Ipamorelin Timing When on Retatrutide: Why morning fasted dosing beats nighttime circadian alignment when GLP-1 is slowing gastric emptying and why the two peptides should never be split up • HGH vs CJC for Muscle Growth Over 50: Why actual HGH wins every time and why splitting the dose morning and night is worth exploring • Benign Pituitary Tumor What Peptides Are Safe: Why HGH and secretagogues are off the table, why creatine and protein are the real answer, and why IGF-1 LR3 still carries risk 📌 Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results. You're a warrior. Act like one. Follow us on social media: JD's Instagram: https://www.instagram.com/jddenhamofficial/ Will's Instagram: https://www.instagram.com/williamthaas/ Join The Community: https://www.skool.com/peptideresearchinstitute/about Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/

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show notes

Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.


Welcome back, warriors! Will's back from Italy engaged! In this week's Peptide Q&A, JD Denham and William T. Haas cover what peptides to stop before blood work, how to sequence a cellular rebuild stack, Tesamorelin timing on Retatrutide, TRT for a truck driver with total T of 396, and why a pituitary tumor changes everything.


Chapters:

00:00 – Intro & Welcome Back

00:40 – The Proposal Story

07:00 – Upcoming Weekend Retreat Announcement

09:00 – Big Guests Coming to the Podcast

11:39 – Q&A: Peptides to Stop Before Blood Work

13:28 – Q&A: Cellular Rebuild Stack & Sequencing

23:22 – Q&A: Sermorelin & Ipamorelin Dosing

29:49 – Q&A: BPC-157 Sublingual vs Oral

32:26 – Q&A: Reconstituted Reta Shelf Life

36:36 – Q&A: TRT Protocol for Low Testosterone

43:14 – Q&A: Timing Tesa/Ipa with Reta

48:25 – Q&A: Combining Multiple Peptides in One Injection

49:20 – Q&A: HGH vs CJC/Ipa Timing with GLP-1

50:36 – Q&A: Muscle Growth Peptides with Pituitary History

53:19 – Prague Trip Recap

59:54 – Outro & Feedback Request


We cover:

• What to Stop Before Blood Work: Why secretagogues, MK-677, HCG, Kisspeptin and biotin can all skew your labs and how long to stop each before testing

• Cellular Rebuild Stack all at Once or Sequenced?: Why Fox04 first clears the trash, why SS-31 must come before MOTS-C, and why throwing the kitchen sink in at once defeats the purpose

• Epithalon Dosing Explained: Why 100 migs twice a year is the standard, why 10 migs for 10 days and 5 migs for 20 days are both correct, and why Paul Bakhtiar starts everyone here

• Sermorelin + Ipamorelin at 260 Down to 238 should You Up the Dose?: Why a caloric deficit blunts IGF-1 response, why winning streaks aren't the time to add more, and how to use plateau busters instead

• BPC-157 Sublingual vs Oral for Gut Health: Why BPC was born in gastric juices and why oral capsules beat sublingual for gut-specific use every time

• How Long Can You Keep a Reconstituted Retatrutide Vial: Why 28 days is the bacteriostatic water standard not a cliff edge and why buying the right vial size solves the problem

• TRT Protocol for a Truck Driver with Total T of 396: Why high body fat raises estrogen and SHBG, why 180-200 migs of test twice weekly is the starting point, and why life changes in three weeks

• Tesamorelin + Ipamorelin Timing When on Retatrutide: Why morning fasted dosing beats nighttime circadian alignment when GLP-1 is slowing gastric emptying and why the two peptides should never be split up

• HGH vs CJC for Muscle Growth Over 50: Why actual HGH wins every time and why splitting the dose morning and night is worth exploring

• Benign Pituitary Tumor What Peptides Are Safe: Why HGH and secretagogues are off the table, why creatine and protein are the real answer, and why IGF-1 LR3 still carries risk


📌 Subscribe for weekly, no-fluff protocols, dosing guidance, and real-world results.


You're a warrior. Act like one.


Follow us on social media:

JD's Instagram: https://www.instagram.com/jddenhamofficial/

Will's Instagram: https://www.instagram.com/williamthaas/

Join The Community: https://www.skool.com/peptideresearchinstitute/about

Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/