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Let's Talk Chemistry- a science podcast by ChemTalk · Oct 6, 2025 · 23 min

Episode 61: Dr. Lance Wells on Glycobiology

The term “glycobiology” may be unfamiliar to many students, as it is an undertaught but extremely important field that is linked to nearly every facet of cellular biology. Glycobiology is the study of carbohydrates, also known as glycans. On this exciting episode of Let’s Talk Chemistry edited by David Alvia, hosts Erin Suh, Jasmine Winter, and Diya Garrepally dive into our interview with Dr. Lance Wells. Dr. Wells shares his research on XLID, an intellectual disability syndrome linked to mutations in OGT, an enzyme that adds a type of glycan, called O-GlcNAc, onto proteins. He also shares how glycans can be used to modify drugs through a process called glycosylation to make them more effective. We hope you enjoy!

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show notes

The term “glycobiology” may be unfamiliar to many students, as it is an undertaught but extremely important field that is linked to nearly every facet of cellular biology. Glycobiology is the study of carbohydrates, also known as glycans. On this exciting episode of Let’s Talk Chemistry edited by David Alvia, hosts Erin Suh, Jasmine Winter, and Diya Garrepally dive into our interview with Dr. Lance Wells. Dr. Wells shares his research on XLID, an intellectual disability syndrome linked to mutations in OGT, an enzyme that adds a type of glycan, called O-GlcNAc, onto proteins. He also shares how glycans can be used to modify drugs through a process called glycosylation to make them more effective. We hope you enjoy!