058 Does mTOR determine your optimal training frequency?

In this episode of Hypertrophy Past & Present, Jake and Chris begin with a classic Clancy Ross full-body routine from the Silver Era, then move into a discussion about training frequency, mTOR, muscle protein synthesis, and whether training again before the previous hypertrophy stimulus has “finished” is actually a problem. Key topics include: • Clancy Ross’ 1940s full-body single set routine • Whether training a muscle every 48 hours can blunt hypertrophy • How repeated bout effect studies can be misapplied to training frequency • Why mTOR signalling is not the same thing as muscle growth • The role of oxidative stress and inflammation in post-workout recovery • How volume, frequency, stress, dieting, and athletic workloads affect recovery • Why the best training frequency is limited by recovery