Could a sleep supplement help reduce chronic pain?

While looking for ways to treat pain in those with musculoskeletal disorders, researchers examined studies in which sleep supplement melatonin had been used. 

A study into the behaviour of immune cells in coeliac disease patients showed surprising results. Instead of being overactive, T cells in coeliac disease were subdued, and didn't survive as long as T cells from healthy people. 

Spinal stimulators have been in use for many years, but the evidence for their benefit, or otherwise has been unclear until now.

References

• Efficacy and effectiveness of melatonin for the management of musculoskeletal pain: a systematic review and meta-analysis of placebo and active controlled trials
• Functional immune profiling reveals CD4+ T cell dysregulation in coeliac disease (Immunology and Cell Biology, 2026)
• Transcutaneous spinal cord stimulation plus locomotor training versus sham-stimulation plus locomotor training in chronic spinal cord injury (eWALK): a multicentre, triple-blind, randomised, sham-controlled trial
• The little-known cause of heart attack in young women
• Worsening Asthma Outcomes in Australian Adults: A Comparison of Stratified Sample Surveys in 2012 and 2021
• Most Australians unaware of 'black triangle' medicine side effects reporting scheme: study
• New pneumococcal vaccine for adults on the NIP
• Statement from Invidior on removal of Sublocade from Australian market