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Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Ep. 584 "Slowing the Engine” – How GLP-1s Alter Your Gut Motility & Microbiome | Menopause, Perimenopause & Gut Health

April 23 · 21 min
0:00-21:13

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Welcome to today’s Midlife Minute.

In this episode, I answer listeners’ questions about GLP-1 medications and midlife weight changes. I explore how hormonal shifts, insulin sensitivity, muscle mass, and the gut microbiome influence the effectiveness of these drugs, and explain why they should be regarded as part of a broader metabolic and lifestyle framework.

IN THIS EPISODE, YOU WILL LEARN:

  • Why GLP-1 medications don’t necessarily fix the root cause of midlife weight gain 

  • How declining estrogen can disrupt your appetite and satiety hormones

  • The value of checking your fasting insulin to understand your insulin sensitivity level

  • How inadequate protein can cause cravings for processed carbohydrates and fats

  • Why preserving muscle mass is critical to prevent sarcopenic obesity  

  • How GLP-1 medications affect digestion and gut motility

  • The clinical factors that are considered when prescribing GLP-1 medications 

  • Some simple daily habits to support your metabolic and microbiome health when using GLP-1 medications 

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