EP Edge® Journal Watch Issue 28, July 2026: Pulsed Field Ablation Goes Mainstream, LAAO vs DOACs, Non-PV Triggers, and LBBAP Lead Position

In EP Edge® Journal Watch Issue 28, July 2026, Dr. Sharma reviews a major month in cardiac electrophysiology, where new technology is being tested against real-world evidence. This episode covers the rapid commercial adoption of pulsed field ablation, the NCDR AFib Ablation Registry, the VOLT-AF IDE balloon-in-basket PFA study, PFA-related intravascular hemolysis, and the evolving role of non-pulmonary vein triggers in first-time AF ablation.

The issue also explores low-cost atrial fibrillation screening with pulse self-exam, next-generation left atrial appendage occlusion with the VERITAS Amulet 360 study, MAUDE registry safety signals for pericardial effusion after Watchman and Amulet, WATCHMAN peridevice leak anatomy by TEE and CT, the randomized evidence comparing LAAC vs DOACs, and whether left bundle branch area pacing lead position matters after conduction system capture.

The central question across the issue: how should electrophysiologists match technology to mechanism, anatomy, substrate, and patient phenotype? The newsletter groups the papers into PFA scale and safety, AF beyond the pulmonary veins, LAAO in the evidence era, and conduction system pacing. 

For full references, graphics, and the written newsletter, visit EP Edge Journal Watch on LinkedIn and Substack.

EP Edge® Journal Watch Issue 28 reviews pulsed field ablation, LAAO vs DOACs, non-PV triggers, AF screening, WATCHMAN leaks, Amulet 360, and LBBAP.

EP Edge Journal Watch, EP Edge podcast, cardiac electrophysiology, electrophysiology podcast, atrial fibrillation, AF ablation, pulsed field ablation, PFA, left atrial appendage occlusion, LAAO, conduction system pacing

Trials
NCDR AFib Ablation Registry, PFA commercial release, VOLT-AF IDE, balloon-in-basket PFA, PFA hemolysis, intravascular hemolysis, non-PV triggers, first-time AF ablation, pulse self-exam, AF screening, VERITAS study, Amulet 360, MAUDE registry, Watchman pericardial effusion, Amulet pericardial effusion, WATCHMAN peridevice leak, LAAC vs DOACs, LBBAP lead position, left bundle branch area pacing, myocardial work, Burri Jastrzębski, Tapia Martínez

Clinical topic keywords:
pulmonary vein isolation, PVI, persistent atrial fibrillation, paroxysmal atrial fibrillation, AF recurrence, AF stroke prevention, device-related thrombus, peridevice leak, TEE, cardiac CT, ischemic stroke, bleeding risk, DOAC therapy, physiologic pacing, left bundle branch pacing, electrophysiology research, Heart Rhythm Society

Show Notes Links

Substack
 https://lnkd.in/e6b2ZrbZ

EP Edge Journal Watch Weekly Newsletter
 https://lnkd.in/e-Wa4diC

EP Edge Newsletter In-Depth Monthly Issues
 https://lnkd.in/ep3NdZUz

EP Edge Podcast
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Spotify: https://lnkd.in/egb6HzPc
Amazon: https://lnkd.in/e2q-xJi6
YouTube: https://lnkd.in/ePSUJCP2