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Dr. Joseph Mercola - Take Control of Your Health

Advanced Heart, Kidney, and Metabolic Disease Linked to Higher Cancer Risk

July 18 · 7 min · 10.1 MB
0:00-7:02

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  • Researchers followed more than 1.39 million adults and found that advanced cardiovascular-kidney-metabolic (CKM) disease was strongly associated with higher cancer risk, especially once people reached the more severe stages tied to insulin resistance, kidney dysfunction, and cardiovascular disease
  • Cancer incidence rose from 81.2 cases per 10,000 person-years in the healthiest group to more than 250 cases per 10,000 person-years in advanced CKM stages (an increase that narrowed to roughly 25% to 30% after adjusting for age and other factors), showing how rapidly risk accelerates once multiple metabolic systems begin failing together
  • Chronic inflammation, insulin resistance and excess dysfunctional body fat may help create a biologic environment associated with higher rates of colorectal, lung, pancreatic, liver, bladder, kidney, and hormone-related cancers
  • Younger adults under 65 with advanced CKM disease showed a 45% higher cancer risk, challenging the idea that metabolic-driven cancer only develops late in life after decades of decline
  • Lowering seed oil intake, improving insulin sensitivity through movement, supporting mitochondrial energy production with sunlight and tracking markers such as HOMA-IR and blood pressure may help slow metabolic deterioration before it reaches the dangerous tipping point tied to higher cancer risk