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Artwork for Dr. John Campbell
Dr. John Campbell · Yesterday · 23 min

Good natural immunity data

Evidence omicron is generating natural immunity. https://www.gov.uk/government/news/covid-19-variants-identified-in-the-uk-latest-updates https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1093275/covid-technical-briefing-44-22-july-2022.pdf Sequenced, 10 July 2022 to 17 July 2022 BA.2 3.4% (0.6% to 8.6%) BA.4 17.2% (12.8%) BA.5 78.7% (77.9%) Others 0.7% Newly designated variant, BA.2.75 Identified as part of horizon scanning on 4 July 2022 BA.2.75 is a sub-lineage of BA.2 8 additional mutations from BA.2 24 cases with BA.2.75 in the UK It has also been identified in multiple other countries in low numbers. Protection of SARS-CoV-2 natural infection against reinfection with the Omicron BA.4 or BA.5 subvariants https://www.medrxiv.org/content/10.1101/2022.07.11.22277448v1 All Qatar’s COVID-19 cases since start of BA.4 / BA.5 wave Study estimates the effectiveness of previous infection in preventing reinfection with Omicron BA.4/BA.5 S-gene target failure proxy for BA.4/BA.5 infections Effectiveness of a previous pre-Omicron infection against symptomatic BA.4/BA.5 reinfection 15.1% against symptomatic reinfection 28.3% against any BA.4/BA.5 reinfection Effectiveness of a previous Omicron infection against symptomatic BA.4/BA.5 reinfection 76.1% against symptomatic reinfection 79.7% against any BA.4/BA.5 reinfection Prior Omicron infection protects against BA.4 and BA.5 https://www.nature.com/articles/d41586-022-01950-2?utm_source=Nature+Briefing&utm_campaign=d266f4379d-briefing-dy-20220722&utm_medium=email&utm_term=0_c9dfd39373-d266f4379d-44762053 Alex Sigal, virologist, Africa Health Research Institute, Durban The time that has passed since your original infection is much shorter with Omicron, so it’s really not a fair comparison UK Health Security Agency 15% of people in England have never had Covid https://www.theguardian.com/world/2022/jul/22/why-do-the-minority-who-havent-had-covid-account-for-most-new-infections https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/datasets/coronaviruscovid19infectionsurveydata About 15% of people in England have never had Covid this minority group still accounts for 55% of infections 45% of cases are now reinfections the lowest it has been since the start of the pandemic, UKHSA estimated more than 10 million people had still never been infected First-time infections More likely to be symptomatic Fewer subsequent infections identified Many people are being reinfected but not noticing So % of reinfections may actually be more than 45% NZ Population 5.1 million https://www.health.govt.nz https://www.health.govt.nz/covid-19-novel-coronavirus/covid-19-data-and-statistics/covid-19-case-demographics Deaths official coded as due to covid = 874 Covid coded as contributing to a death = 475 Learn more about your ad choices. Visit megaphone.fm/adchoices

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Evidence omicron is generating natural immunity. https://www.gov.uk/government/news/covid-19-variants-identified-in-the-uk-latest-updates https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1093275/covid-technical-briefing-44-22-july-2022.pdf Sequenced, 10 July 2022 to 17 July 2022 BA.2 3.4% (0.6% to 8.6%) BA.4 17.2% (12.8%) BA.5 78.7% (77.9%) Others 0.7% Newly designated variant, BA.2.75 Identified as part of horizon scanning on 4 July 2022 BA.2.75 is a sub-lineage of BA.2 8 additional mutations from BA.2 24 cases with BA.2.75 in the UK It has also been identified in multiple other countries in low numbers. Protection of SARS-CoV-2 natural infection against reinfection with the Omicron BA.4 or BA.5 subvariants https://www.medrxiv.org/content/10.1101/2022.07.11.22277448v1 All Qatar’s COVID-19 cases since start of BA.4 / BA.5 wave Study estimates the effectiveness of previous infection in preventing reinfection with Omicron BA.4/BA.5 S-gene target failure proxy for BA.4/BA.5 infections Effectiveness of a previous pre-Omicron infection against symptomatic BA.4/BA.5 reinfection 15.1% against symptomatic reinfection 28.3% against any BA.4/BA.5 reinfection Effectiveness of a previous Omicron infection against symptomatic BA.4/BA.5 reinfection 76.1% against symptomatic reinfection 79.7% against any BA.4/BA.5 reinfection Prior Omicron infection protects against BA.4 and BA.5 https://www.nature.com/articles/d41586-022-01950-2?utm_source=Nature+Briefing&utm_campaign=d266f4379d-briefing-dy-20220722&utm_medium=email&utm_term=0_c9dfd39373-d266f4379d-44762053 Alex Sigal, virologist, Africa Health Research Institute, Durban The time that has passed since your original infection is much shorter with Omicron, so it’s really not a fair comparison UK Health Security Agency 15% of people in England have never had Covid https://www.theguardian.com/world/2022/jul/22/why-do-the-minority-who-havent-had-covid-account-for-most-new-infections https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/datasets/coronaviruscovid19infectionsurveydata About 15% of people in England have never had Covid this minority group still accounts for 55% of infections 45% of cases are now reinfections the lowest it has been since the start of the pandemic, UKHSA estimated more than 10 million people had still never been infected First-time infections More likely to be symptomatic Fewer subsequent infections identified Many people are being reinfected but not noticing So % of reinfections may actually be more than 45% NZ Population 5.1 million https://www.health.govt.nz https://www.health.govt.nz/covid-19-novel-coronavirus/covid-19-data-and-statistics/covid-19-case-demographics Deaths official coded as due to covid = 874 Covid coded as contributing to a death = 475

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