Dhru Purohit Show: Dr. Perlmutter on Why Alzheimer’s Science Got It Wrong

Alzheimer’s may be less about amyloid plaques and more about a breakdown in the brain’s immune and metabolic systems. In this concise recap of Dhru Purohit’s conversation with Dr. David Perlmutter on the Dhru Purohit Show, you’ll get the key ideas from the full-length episode in a minutes-long summary. Perlmutter explains how microglia, inflammation, blood sugar, sleep, exercise, gut health, and ultra-processed food may all shape dementia risk—and why lifestyle changes may help protect cognition, support brain health, and potentially slow or even reverse early decline. He also discusses the gut-brain connection, environmental toxins, and why GLP-1 drugs may be a clue that metabolism matters in Alzheimer’s and Parkinson’s disease. Listen now to get the key ideas in minutes.