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16 Minutes News by a16z

Andreessen Horowitz

16 Minutes on the News is a short news podcast where we cover the top headlines of the week, the a16z podcast way -- why are these topics in the news; what's real, what's hype from our vantage point; and what are our experts' quick takes on these trends?

About the a16z Podcast: Discusses tech and culture trends, news, and the future -- especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes -- and now shows -- are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

  • 71 episodes
  • Updated Feb 22, 2022

Episodes71

  • Feb 22, 2022 · 38 min

    Parasite, the Malaria (Tech & Science) Edition

    with @rvenkayya @jorgecondebio @smc90 As with all of the episodes on this show about tech & science trends in the news, and where they are on the long arc of innovation -- this one is actually a story of human ingenuity over 100 years in the making, with the ultimate breakthrough in a malaria vaccine just last year. How is fighting a parasite vs a virus different?

  • Dec 20, 2021 · 12 min

    Crypto at Congress: 'Watershed' Moment for Regulation and Web3

    Welcome to 16 Minutes, our podcast where we discuss tech trends in the news and their impact on the long arc of innovation. Today’s topic is crypto regulation, and specifically, two recent federal government hearings in the news that were focused on crypto and therefore the related trend of web3. In contrast to the model of web2 — typified by very broadly used but also very centralized platforms run by corporations — web3 refers to the idea of a new internet enabled by crypto that is owned by bu

  • Dec 3, 2021 · 21 min

    Inside the GameStop Drama; The U.S. Constitution, Auctioned

    Welcome to 16 Minutes, our show on the a16z podcast network where we talk about tech trends that are dominating news headlines, industry buzz, and where we are on the long arc of innovation. Today’s episode actually features a look back at the GameStop saga — the stock market drama that some headlines described as a “David-and-Goliath battle” that quote “upended Wall Street.” For quick basic context, here’s what happened: A group of Reddit users mass-purchased and drove up prices of stock in

  • Oct 26, 2021 · 20 min

    Steam Halts Web3 Games; FDA Approves Prostate Cancer AI

    Welcome to 16 Minutes, our show where we talk about tech trends in the news. We have two segments today: 1) The announcement recently that Valve Software, which operates the massive gaming platform Steam, added a rule against games that use blockchain technologies or that allow users to exchange cryptocurrencies or NFTs – this rule appeared on its “What you shouldn’t publish on Steam” onboarding list for developers. We go beyond the players to the trends at play here, putting the news in contex

  • Aug 2, 2021 · 16 min

    mRNA for Flu Vaccine? AI Protein-Folding Goes Open Source

    In today’s episode we have two short segments, both on bioscience topics: [0:00] Moderna has started clinical trials for a flu vaccine, called mRNA-1010, that is based on the same mRNA technology that Moderna and Pfizer used for their COVID vaccines, and that several other companies including Sanofi and Glaxo all are actively working on for the influenza use case. Our experts are general partners Vineeta Agarwala and Jorge Conde of the a16z bio team, who have joined us on many of our vaccine-re

  • Jul 26, 2021 · 18 min

    Opioid Crisis - How, Who, and Tech

    with @jorgecondebio @vijaypande @smc90 Given recent news of drug company settlements, policy moves, and more, this episode is a rerun of one of our early explainers on the opioid crisis -- how do opioids work; who's to blame; and where does (and doesn't) tech come in?

  • Jun 9, 2021 · 12 min

    Ransomware Attacks on the Rise; Hackers Target IoT

    Welcome to 16 Minutes, the a16z show where we talk about tech trends in the news, what’s hype and what’s real, and the long arc of innovation. In today's episode we’re talking about the latest developments and trends in cybercrime – including the trends of ransomware, and, attacks on physical infrastructure. First (0:00 - 6:07), we have the recent attack on the meat processing plant JBS, the largest meat processor in the world; just last week it had to temporarily shut down some operations in

  • May 25, 2021 · 10 min

    Science (and Tech), the Endless Frontier

    with @martin_casado @smc90 Given recent news and discussions around the Endless Frontiers Act, we re-released this episode about that and innovation funding/ R&D

  • May 2, 2021 · 36 min

    Malaria Vaccine Breakthrough, Beyond the Buzz

    with @jorgecondebio @rvenkayya @smc90 In this special 2x explainer episode, we dig into what's hype/ what's real about news of a breakthrough malaria vaccine candidate, beyond the headlines and beyond the buzz: data, science, tech, innovation.

  • Apr 25, 2021 · 13 min

    Apple Event: Desktop-Tablet Convergence, Cord-Cutting, "Find Anything," & More

    In this week’s episode of 16 Minutes, our show where we cover tech trends in the news — and also cover themes from company developer and innovation events! — we focus on the latest coming out of Apple’s event this week. The company announced a bunch of things, ranging from new device colors and form factors to podcast services, but in this episode we asked regular guest Steven Sinofsky (an a16z board partner and former Microsoft Windows president who has appeared on past event episodes including

  • Apr 19, 2021 · 15 min

    J&J Vaccine Pause; FBI Accesses Servers in Exchange Hack

    We have two brief segments in today’s episode: News and analysis of the Johnson & Johnson COVID vaccine pause, and the widespread hack of Microsoft Exchange Servers across the country (and the dramatic and unusual steps the FBI took in response). Johnson & Johnson: Federal health officials last week revealed that six women who received the vaccine had developed rare and severe blood clots in their brain, in one case fatally. Even more recently, a panel of expert advisors to the Centers for Dise

  • Mar 28, 2021 · 56 min

    NFTs: What, Where, How, Why, Who

    with @ljxie @jessewldn @smc90 This deep-dive (one of our 3-4X explainer episodes here) teases apart what's hype/ what's real and the what, where, how, why, who -- answering questions top of mind around all things NFTs.

  • Mar 20, 2021 · 18 min

    The U.S. Vaccine Rollout

    Today on our news analysis show 16 Minutes — since this show is all about teasing apart what’s hype/ what’s real and where we are on the long arc of innovation — we're taking a quick pulse-check with the experts on just where we are with the COVID vaccine rollout in the U.S.  Our experts today are Dr. Bob Wachter, the Chair of the Department of Medicine at UCSF — he has come to additional prominence during the pandemic as a regular public resource, providing daily updates & reports on Twitter t

  • Mar 16, 2021 · 12 min

    The Johnson & Johnson Vaccine and COVID Efficacy Rates

    In today's episode of our news analysis show 16 Minutes, our topic is the ongoing buzz and the mixed news around the Johnson & Johnson vaccine, which was the third vaccine for COVID approved under Emergency Use Authorization by the FDA just a few weeks ago. Johnson & Johnson reported it as “the first single shot vaccine” and as having 85% efficacy in preventing severe disease across regions studied; meanwhile, STAT headlines reported 66% efficacy overall and 72% in the U.S. in preventing moderat

  • Mar 7, 2021 · 17 min

    Semiconductor Shortage and the Global Supply Chain Squeeze

    In this week’s episode of 16 Minutes, our show where we talk about tech trends in the news, what’s hype/ what’s real, and where we are on the long arc of innovation, the topic is semiconductors – specifically, the ongoing global shortage that began last summer and has intensified in recent weeks. So much so, that the U.S. president signed an executive order just last week to address concerns around the shortage, calling for reviews of supply chains for critical sectors of the economy. Our expe

  • Feb 25, 2021 · 12 min

    When Christie's Meets Crypto — The NFT Moment

    In this week’s episode of 16 Minutes — where we talk about tech trends in the news, what’s hype/ what’s real, and where we are on the long arc of innovation — the topic is NFTs ("non-fungible tokens"); specifically, the news that Christie’s has become the first major auction house to offer a purely digital artwork tied to an NFT or “non-fungible token." We’ll go more into NFTs (as well as whether this is really a big deal or not) in this episode, but here’s the news context: The work of art be

  • Feb 20, 2021 · 11 min

    China Steams Ahead in Gaming; MetaHuman Creator and the Uncanny Valley

    We have two brief segments — taking up less than 16 Minutes! — in this week’s episode of "16 Minutes," where we talk about tech trends in the news, what’s hype/what’s real, and where we are on the long arc of innovation. Both segments touch on trends in gaming/ online worlds and entertainment — both now and "next."  First, Steam China: Steam — the cloud library and marketplace for buying, selling, and storing games that was launched by Valve in 2003 and is now the largest distribution platform

  • Feb 6, 2021 · 17 min

    Beyond Bezos: Amazon, Cloud, and CEO Transitions

    with @martin_casado @zoranbasich @smc90 Amazon just announced that its founder and CEO Jeff Bezos will transition to the role of Executive Chair and that CEO of Amazon Web Services Andy Jassy will become CEO. So in this episode of 16 Minutes, we talk not just about this news, but what it signals regarding cloud computing as well as CEO transitions in general. Especially given other recent cases and more.

  • Feb 1, 2021 · 48 min

    Anatomy of a Hack: SolarWinds and Ripples Beyond

    with @stevenadair joeldelagarza @smc90 In this special “3x”-long episode of our (otherwise shortform) news analysis show 16 Minutes, we cover the SolarWinds hack, one of the largest known hacks of all time... and the ripple effects are only now starting to be revealed, especially given latest news reports from the U.S. government. What actually happened, when does the timeline really begin? We help cut through the headline fatigue of it in this "anatomy of a hack" teardown -- the who, what, whe

  • Jan 26, 2021 · 20 min

    Dall-E AI for Images; Direct Listings, SEC Ruling for Issuing Shares

    We've got segments on artificial intelligence and IPO innovation in today's episode of 16 Minutes, where we take a look at the news and what it means for the long arc of innovation. In the first segment (0:00): Take the surrealistic images of Salvador Dali and cross them with Pixar's animated film Wall-E and you've got ... Dall-E! It's a new neural network that creates images based on text inputs, and the worlds of A.I. and machine learning recently got their first glimpse. Last summer, research lab OpenAI released an API for the machine learning model GPT-3, which caused a stir with the way it could produce text that was hard to distinguish from human writing (16 Minutes showrunner Sonal Choksi and a16z Operating Partner Frank Chen discussed it in a recent 16 Minutes Podcast, "GPT-3: Beyond the Hype," breaking down what it does and doesn't mean for startups, incumbents, and the idea of "AI as a service"). Now OpenAI has unveiled Dall-E, which processes language to create new images (not new text, as GPT-3 does). Dall-E does this using a neural network called CLIP (Contrastive Language-Image Pre-training), which classifies a wide variety of images culled from the internet while "filling in the blanks" using zero-shot reasoning, enabling Dall-E to produce surprising images by inferring information it wasn't trained in. We called on Frank again to explain where Dall-E (and the broader topic of machine learning) sits on the path toward artificial general intelligence (AGI), how Dall-E's transformer-type architecture is able to infer information, what its limitations might be, and what uses we might see as this technology develops. -- with Zoran Basich In the second segment (12:58), we had a quick chat with a16z operating partner Scott Kupor about the recent decision by the SEC to allow the issuance of new shares via direct listings on the New York Stock Exchange. Previously direct listings were limited to the sale of existing shares. Recent first-day IPO "pops" have sparked much discussion about the fairness or unfairness of the process and whether the current path we have for companies going public is broken or just needs some tinkering around the edges. Scott breaks down how the new rule will affect companies, as well as institutional and retail investors, and what this means in the long arc of IPO innovation. -- with Zoran Basich --- The views expressed here are those of the individual AH Capital Management, L.L.C. (“a16z”) personnel quoted and are not the views of a16z or its affiliates. Certain information contained in here has been obtained from third-party sources, including from portfolio companies of funds managed by a16z. While taken from sources believed to be reliable, a16z has not independently verified such information and makes no representations about the enduring accuracy of the information or its appropriateness for a given situation. In addition, this content may include third-party advertisements; a16z has not reviewed such advertisements and does not endorse any advertising content contained therein This content is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. You should consult your own advisers as to those matters. References to any securities or digital assets are for illustrative purposes only, and do not constitute an investment recommendation or offer to provide investment advisory services. Furthermore, this content is not directed at nor intended for use by any investors or prospective investors, and may not under any circumstances be relied upon when making a decision to invest in any fund managed by a16z. 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